Search Results - "Sahún, I."

Motor phenotypic alterations in TgDyrk1a transgenic mice implicate DYRK1A in Down syndrome motor dysfunction by Martı́nez de Lagrán, M, Altafaj, X, Gallego, X, Martı́, E, Estivill, X, Sahún, I, Fillat, C, Dierssen, M

“…Motor deficits are among the most frequent impairments in Down syndrome (DS), but their neuropathological and molecular bases remain elusive. Here we…”
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Candidate genes for panic disorder: insight from human and mouse genetic studies by Gratacòs, M., Sahún, I., Gallego, X., Amador‐Arjona, A., Estivill, X., Dierssen, M.

“…Panic disorder is a major cause of medical attention with substantial social and health service cost. Based on pharmacological studies, research on its…”
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Differential responses to anxiogenic drugs in a mouse model of panic disorder as revealed by Fos immunocytochemistry in specific areas of the fear circuitry by Sahún, I, Gallego, X, Gratacòs, M, Murtra, P, Trullás, R, Maldonado, R, Estivill, X, Dierssen, M

“…Sensitivity to pharmacological challenges has been reported in patients with panic disorder. We have previously validated transgenic mice overexpressing the…”
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Targeting Dyrk1A with AAVshRNA Attenuates Motor Alterations in TgDyrk1A, a Mouse Model of Down Syndrome by Ortiz-Abalia, Jon, Sahún, Ignasi, Altafaj, Xavier, Andreu, Núria, Estivill, Xavier, Dierssen, Mara, Fillat, Cristina

“…Genetic-dissection studies carried out with Down syndrome (DS) murine models point to the critical contribution of Dyrk1A overexpression to the motor…”
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