Search Results - "Sagoo, Mandeep S"

Phase 1 clinical study of an embryonic stem cell–derived retinal pigment epithelium patch in age-related macular degeneration by da Cruz, Lyndon, Fynes, Kate, Georgiadis, Odysseas, Kerby, Julie, Luo, Yvonne H, Ahmado, Ahmad, Vernon, Amanda, Daniels, Julie T, Nommiste, Britta, Hasan, Shazeen M, Gooljar, Sakina B, Carr, Amanda-Jayne F, Vugler, Anthony, Ramsden, Conor M, Bictash, Magda, Fenster, Mike, Steer, Juliette, Harbinson, Tricia, Wilbrey, Anna, Tufail, Adnan, Feng, Gang, Whitlock, Mark, Robson, Anthony G, Holder, Graham E, Sagoo, Mandeep S, Loudon, Peter T, Whiting, Paul, Coffey, Peter J

“…An engineered patch of retinal pigment epithelium generated from human embryonic stem cells is transplanted into the eyes of two patients. Age-related macular…”
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Automatic data-driven design and 3D printing of custom ocular prostheses by Reinhard, Johann, Urban, Philipp, Bell, Stephen, Carpenter, David, Sagoo, Mandeep S.

“…Millions of people require custom ocular prostheses due to eye loss or congenital defects. The current fully manual manufacturing processes used by highly…”
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Epidemiology of ocular surface squamous neoplasia in Africa by Gichuhi, Stephen, Sagoo, Mandeep S., Weiss, Helen A., Burton, Matthew J.

“…ObjectivesTo describe the epidemiology and an aetiological model of ocular surface squamous neoplasia (OSSN) in Africa. MethodsSystematic and non‐systematic…”
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Pathophysiology of ocular surface squamous neoplasia by Gichuhi, Stephen, Ohnuma, Shin-ichi, Sagoo, Mandeep S., Burton, Matthew J.

“…The incidence of ocular surface squamous neoplasia (OSSN) is strongly associated with solar ultraviolet (UV) radiation, HIV and human papilloma virus (HPV)…”
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Primary intraocular lymphoma by Sagoo, Mandeep S., MB, PhD, MRCOphth, FRCS (Ed), Mehta, Hemal, MA, FRCOphth, Swampillai, Andrew J., MB, BS, Cohen, Victoria M.L., MB, BChir, FRCOphth, Amin, Sepideh Z., MBChB, FRCOphth, PhD, FRCPath, Plowman, P. Nicholas, FRCP, FRCR, Lightman, Sue, PhD, FRCP, FRCOphth

“…Abstract Primary intraocular lymphoma (PIOL) is an ocular malignancy that is a subset of primary central system lymphoma (PCNSL). Approximately one-third of…”
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Efficacy and Complications of Super-selective Intra-ophthalmic Artery Melphalan for the Treatment of Refractory Retinoblastoma by Muen, Wisam J., MRCS.Ed(Surg), FRCOphth, Kingston, Judith E., FRCP, FRCPCH, Robertson, Fergus, MRCP, FRCR, Brew, Stefan, MSc, FRANZCR, Sagoo, Mandeep S., PhD, FRCS (Ed), Reddy, M. Ashwin, MD, FRCOphth

“…Purpose To report the efficacy of super-selective intra-ophthalmic artery melphalan (IAM) for the treatment of refractory retinoblastoma and any associated…”
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High-Risk Histopathology Features in Primary and Secondary Enucleated International Intraocular Retinoblastoma Classification Group D Eyes by Fabian, Ido D., MD, Stacey, Andrew W., MD, Chowdhury, Tanzina, MRCPCH, PhD, Duncan, Catriona, MBBS, MRCPCH, Karaa, Esin K., MD, Scheimberg, Irene, MD, Reddy, M. Ashwin, MD, FRCOphth, Sagoo, Mandeep S., PhD, FRCS(Ed)

“…Purpose To evaluate the rate and identify the risk factors for high-risk histopathologic features in group D retinoblastoma eyes enucleated as primary or…”
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Is Tumour Thickness Measurement Required for MOLES Scoring of Melanocytic Choroidal Tumours? by Ching, Jared, AlHarby, Lamis, Sagoo, Mandeep S., Damato, Bertil

“…Introduction: It can be challenging to distinguish between choroidal naevi and melanomas in the community setting, particularly without access to…”
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PRELP Regulates Cell–Cell Adhesion and EMT and Inhibits Retinoblastoma Progression by Hopkins, Jack, Asada, Ken, Leung, Alex, Papadaki, Vasiliki, Davaapil, Hongorzul, Morrison, Matthew, Orita, Tomoko, Sekido, Ryohei, Kosuge, Hirofumi, Reddy, M. Ashwin, Kimura, Kazuhiro, Mitani, Akihisa, Tsumoto, Kouhei, Hamamoto, Ryuji, Sagoo, Mandeep S., Ohnuma, Shin-ichi

“…Retinoblastoma (RB) is the most common intraocular pediatric cancer. Nearly all cases of RB are associated with mutations compromising the function of the RB1…”
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Genetic analysis of ocular tumour-associated genes using large genomic datasets: insights into selection constraints and variant representation in the population by Tanner, Alexander, Sagoo, Mandeep S, Mahroo, Omar A, Pulido, Jose S

“…BackgroundLarge genomic databases enable genetic evaluation in terms of haploinsufficiency and prevalence of missense and synonymous variants. We explored…”
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The Fate of RPE Cells Following hESC-RPE Patch Transplantation in Haemorrhagic Wet AMD: Pigmentation, Extension of Pigmentation, Thickness of Transplant, Assessment for Proliferation and Visual Function-A 5 Year-Follow Up by da Cruz, Lyndon, Soomro, Taha, Georgiadis, Odysseas, Nommiste, Britta, Sagoo, Mandeep S, Coffey, Peter

“…(1) Background: We reviewed a stem cell-derived therapeutic strategy for advanced neovascular age-related macular degeneration (nAMD) using a human embryonic…”
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Whole-Genome Sequencing of Retinoblastoma Reveals the Diversity of Rearrangements Disrupting RB1 and Uncovers a Treatment-Related Mutational Signature by Davies, Helen R, Broad, Kevin D, Onadim, Zerrin, Price, Elizabeth A, Zou, Xueqing, Sheriff, Ibrahim, Karaa, Esin Kotiloğlu, Scheimberg, Irene, Reddy, M Ashwin, Sagoo, Mandeep S, Ohnuma, Shin-Ichi, Nik-Zainal, Serena

“…The development of retinoblastoma is thought to require pathological genetic changes in both alleles of the gene. However, cases exist where mutations are…”
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Subconjunctival Ocular Argyrosis following Treatment with Ruthenium 106 Brachytherapy for Choroidal Melanoma by Khasati, Aya, Thaung, Caroline, Mudhar, Hardeep Singh, Wagner, Bart, Goggin, Patricia, Stoker, Ian, Sagoo, Mandeep S., Damato, Bertil, Quhill, Hibba

“…Introduction: Ruthenium-106 (Ru-106) brachytherapy is one of the commonest eye-sparing treatments for choroidal melanoma. These patients require long-term…”
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Classification and staging of retinoblastoma by Fabian, Ido Didi, Reddy, Ashwin, Sagoo, Mandeep S

“…Classifying and staging retinoblastoma is an essential first step when planning how to manage a child with the condition; it also gives important information…”
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PRELP secreted from mural cells protects the function of blood brain barrier through regulation of endothelial cell-cell integrity by Davaapil, Hongorzul, Hopkins, Jack, Bonnin, Nadia, Papadaki, Vasiliki, Leung, Alex, Kosuge, Hirofumi, Tashima, Takumi, Nakakido, Makoto, Sekido, Ryohei, Tsumoto, Kouhei, Sagoo, Mandeep S., Ohnuma, Shin-Ichi

“…Introduction: Proline/arginine-rich end leucine-rich repeat protein (PRELP), is a small secreted proteoglycan expressed by pericytes and vascular smooth muscle…”
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Two Secreted Proteoglycans, Activators of Urothelial Cell-Cell Adhesion, Negatively Contribute to Bladder Cancer Initiation and Progression by Papadaki, Vasiliki, Asada, Ken, Watson, Julie K, Tamura, Toshiya, Leung, Alex, Hopkins, Jack, Dellett, Margaret, Sasai, Noriaki, Davaapil, Hongorzul, Nik-Zainal, Serena, Longbottom, Rebecca, Nakakido, Makoto, Torii, Ryo, Veerakumarasivam, Abhi, Kaneko, Syuzo, Sagoo, Mandeep S, Murphy, Gillian, Mitani, Akihisa, Tsumoto, Kohei, Kelly, John D, Hamamoto, Ryuji, Ohnuma, Shin-Ichi

“…Osteomodulin (OMD) and proline/arginine-rich end leucine repeat protein (PRELP) are secreted extracellular matrix proteins belonging to the small leucine-rich…”
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Repeatability of swept-source optical coherence tomography retinal and choroidal thickness measurements in neovascular age-related macular degeneration by Hanumunthadu, Daren, Ilginis, Tomas, Restori, Marie, Sagoo, Mandeep S, Tufail, Adnan, Balaggan, Kamaljit S, Patel, Praveen J

“…The aim was to determine the intrasession repeatability of swept-source optical coherence tomography (SS-OCT)-derived retinal and choroidal thickness…”
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Germline retinoblastoma: estimating risk and counselling the family by Rosser, Elisabeth, Sagoo, Mandeep S

“…Even when a diagnosis of germline retinoblastoma cannot be confirmed by genetic testing, the risk to family can still be estimated and used to plan follow-up…”
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Ruthenium-106 Plaque Brachytherapy in the Primary Management of Ocular Medulloepithelioma by Poon, Daniel S., MB, BS, Reich, Ehud, MD, Smith, Victoria M., BM Sci, Kingston, Judith, FRCP, FRCPCH, Reddy, M. Ashwin, MD, FRCOphth, Hungerford, John L., FRCS, FRCOphth, Sagoo, Mandeep S., MB, PhD

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Delay along the care-seeking journey of patients with ocular surface squamous neoplasia in Kenya by Gichuhi, Stephen, Kabiru, Joy, M'bongo Zindamoyen, Alain, Rono, Hillary, Ollando, Ernest, Wachira, Joseph, Munene, Rhoda, Onyuma, Timothy, Sagoo, Mandeep S, Macleod, David, Weiss, Helen A, Burton, Matthew J

“…In Africa, accessing eye health services is a major challenge. Ocular surface squamous neoplasia (OSSN) is a substantial ocular health problem in Africa…”
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