Search Results - "Sagnou, Marina"

Pyrazoline Hybrids as Promising Anticancer Agents: An Up-to-Date Overview by Matiadis, Dimitris, Sagnou, Marina

“…Pyrazolines are five-membered heterocycles possessing two adjacent nitrogens. They have attracted significant attention from organic and medicinal chemists due…”
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Advanced bis-MPA hyperbranched dendritic nanocarriers of artemisinin with anticancer potential by Halevas, Eleftherios, Mavroidi, Barbara, Kokotidou, Chrysoula, Mitraki, Anna, Pelecanou, Maria, Sagnou, Marina

“…In this work, a dendritic–linear–dendritic hybrid copolymer based on hyperbranched 2,2-bis(hydroxymethyl)propionic acid (bis-MPA) and linear polyethylene…”
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Synthesis and antimicrobial evaluation of a pyrazoline-pyridine silver(I) complex: DNA-interaction and anti-biofilm activity by Matiadis, Dimitris, Karagiaouri, Maria, Mavroidi, Barbara, Nowak, Katarzyna E., Katsipis, Georgios, Pelecanou, Maria, Pantazaki, Anastasia, Sagnou, Marina

“…The emergence of resistant bacterial strains mainly due to misuse of antibiotics has seriously affected our ability to treat bacterial illness, and the…”
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Curcumin Derivatives as Potential Mosquito Larvicidal Agents against Two Mosquito Vectors, Culex pipiens and Aedes albopictus by Matiadis, Dimitris, Liggri, Panagiota G V, Kritsi, Eftichia, Tzioumaki, Niki, Zoumpoulakis, Panagiotis, Papachristos, Dimitrios P, Balatsos, George, Sagnou, Marina, Michaelakis, Antonios

“…Vector-borne diseases have appeared or re-emerged in many Southern Europe countries making the transmission of infectious diseases by mosquitoes (vectors) one…”
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Small Multitarget Molecules Incorporating the Enone Moiety by Liargkova, Thalia, Eleftheriadis, Nikolaos, Dekker, Frank, Voulgari, Efstathia, Avgoustakis, Constantinos, Sagnou, Marina, Mavroidi, Barbara, Pelecanou, Maria, Hadjipavlou-Litina, Dimitra

“…Chalcones represent a class of small drug/druglike molecules with different and multitarget biological activities. Small multi-target drugs have attracted…”
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The ability of apolipoprotein E fragments to promote intraneuronal accumulation of amyloid beta peptide 42 is both isoform and size-specific by Dafnis, Ioannis, Argyri, Letta, Sagnou, Marina, Tzinia, Athina, Tsilibary, Effie C., Stratikos, Efstratios, Chroni, Angeliki

“…The apolipoprotein (apo) E4 isoform is the strongest risk factor for late-onset Alzheimer’s disease (AD). ApoE4 is more susceptible to proteolysis than apoE2…”
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Synthesis of Hydroxyapatite, β-Tricalcium Phosphate and Biphasic Calcium Phosphate Particles to Act as Local Delivery Carriers of Curcumin: Loading, Release and In Vitro Studies by Xidaki, Despoina, Agrafioti, Panagiota, Diomatari, Dimitra, Kaminari, Archontia, Tsalavoutas-Psarras, Eleftherios, Alexiou, Polyxeni, Psycharis, Vasilios, Tsilibary, Effie C, Silvestros, Spyridon, Sagnou, Marina

“…The successful synthesis of hydroxyapatite (HA), β-Tricalcium phosphate (β-TCP) and two biphasic mixtures (BCPs) of the two was performed by means of wet…”
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Phenotypic and Target-Directed Screening Yields New Acaricidal Alternatives for the Control of Ticks by Saporiti, Tatiana, Cabrera, Mauricio, Bentancur, Josefina, Ferrari, María Elisa, Cabrera, Nallely, Pérez-Montfort, Ruy, Aguirre-Crespo, Francisco J, Gil, Jorge, Cuore, Ulises, Matiadis, Dimitris, Sagnou, Marina, Alvarez, Guzmán

“…, the "common cattle tick", is the most important ectoparasite in livestock worldwide due to the economic and health losses it produces. This tick is a vector…”
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The Prophylactic and Multimodal Activity of Two Isatin Thiosemicarbazones against Alzheimer’s Disease In Vitro by Mavroidi, Barbara, Kaminari, Archontia, Matiadis, Dimitris, Hadjipavlou-Litina, Dimitra, Pelecanou, Maria, Tzinia, Athina, Sagnou, Marina

“…Alzheimer’s disease (AD) is a multifactorial disorder strongly involving the formation of amyloid-β (Aβ) oligomers, which subsequently aggregate into the…”
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Monocarbonyl Curcumin Analogues as Potent Inhibitors against Human Glutathione Transferase P1-1 by Pantiora, Panagiota, Furlan, Veronika, Matiadis, Dimitris, Mavroidi, Barbara, Perperopoulou, Fereniki, Papageorgiou, Anastassios C, Sagnou, Marina, Bren, Urban, Pelecanou, Maria, Labrou, Nikolaos E

“…The isoenzyme of human glutathione transferase P1-1 (hGSTP1-1) is involved in multi-drug resistance (MDR) mechanisms in numerous cancer cell lines. In the…”
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A Monocarbonyl Curcuminoid Derivative Inhibits the Activity of Human Glutathione Transferase A4-4 and Chemosensitizes Glioblastoma Cells to Temozolomide by Tsouri, Steliana, Tselo, Evanthia, Premetis, Georgios E, Furlan, Veronika, Pantiora, Panagiota D, Mavroidi, Barbara, Matiadis, Dimitris, Pelecanou, Maria, Papageorgiou, Anastassios C, Bren, Urban, Sagnou, Marina, Labrou, Nikolaos E

“…Human glutathione transferase A4-4 (hGSTA4-4) displays high catalytic efficiency towards 4-hydroxyalkenals and other cytotoxic and mutagenic products of…”
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E)-(1-(4-Ethoxycarbonylphenyl)-5-(3,4-dimethoxyphenyl)-3-(3,4-dimethoxystyryl)-2-pyrazoline: Synthesis, Characterization, DNA-Interaction, and Evaluation of Activity Against Drug-Resistant Cell Lines by Matiadis, Dimitris, Mavroidi, Barbara, Panagiotopoulou, Angeliki, Methenitis, Constantinos, Pelecanou, Maria, Sagnou, Marina

“…(E)-1-(4-Ethoxycarbonylphenyl)-5-(3,4-dimethoxyphenyl)-3-(3,4-dimethoxystyryl)-2-pyrazoline was synthesized via the cyclization reaction between the…”
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Synthesis and Structural Characterization of (E)-4-[(2-Hydroxy-3-methoxybenzylidene)amino]butanoic Acid and Its Novel Cu(II) Complex by Halevas, Eleftherios, Hatzidimitriou, Antonios, Mavroidi, Barbara, Sagnou, Marina, Pelecanou, Maria, Matiadis, Dimitris

“…A novel Cu(II) complex based on the Schiff base obtained by the condensation of ortho-vanillin with gamma-aminobutyric acid was synthesized. The compounds are…”
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A Tridentate Cu(II) Complex with a 2-(4′-Aminophenyl)Benzothiazole Derivative: Crystal Structure and Biological Evaluation for Anticancer Activity by Mavroidi, Barbara, Sagnou, Marina, Halevas, Eleftherios, Mitrikas, George, Kapiris, Fotis, Bouziotis, Penelope, Hatzidimitriou, Antonios G., Pelecanou, Maria, Methenitis, Constantinos

“…Herein, the synthesis, structural characterization and in vitro biological evaluation of a novel Cu(II) complex with the 2-(4-aminophenyl)benzothiazole…”
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Synthesis and Biological Evaluation of Hydroxylated Monocarbonyl Curcumin Derivatives as Potential Inducers of Neprilysin Activity by Matiadis, Dimitris, Ng, See-Ting, Chen, Eric H.-L., Nigianni, Georgia, Vidali, Veroniki P., Canko, Aleksander, Chen, Rita P.-Y., Sagnou, Marina

“…Background: Alzheimer’s disease (AD) involves impairment of Aβ clearance. Neprilysin (NEP) is the most efficient Aβ peptidase. Enhancement of the activity or…”
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Synthesis of Novel Pyrazolo[3,4-b]pyridines with Affinity for β-Amyloid Plaques by Vidali, Veroniki P., Nigianni, Georgia, Athanassopoulou, Georgia D., Canko, Aleksander, Mavroidi, Barbara, Matiadis, Dimitris, Pelecanou, Maria, Sagnou, Marina

“…Three novel pyrazolo[3,4-b]pyridines were synthesized via the cyclization of 5-amino-1-phenylpyrazole with the corresponding unsaturated ketone in the…”
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Naked-eye colorimetric cyanide detection by monocarbonyl analogue of curcumin by Matiadis, Dimitris, Fountzoula, Christina, Trapali, Maria, Karkalousos, Petros, Sagnou, Marina

“…•An easy-to-synthesize curcumin analogue has shown cyanide ion sensing properties•Both colorimetric and "naked-eye" detection of CN− were achieved•Probe…”
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Novel Isatin Thiosemicarbazone Derivatives as Potent Inhibitors of β‑Amyloid Peptide Aggregation and Toxicity by Sagnou, Marina, Mavroidi, Barbara, Kaminari, Archontia, Boukos, Nikos, Pelecanou, Maria

“…Inhibition of β-amyloid peptide (Αβ) aggregation in Alzheimer’s disease (AD) is among the therapeutic approaches against AD which still attracts scientific…”
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Anti-Inflammatory and Neuroprotective Polyphenols Derived from the European Olive Tree, Olea europaea L., in Long COVID and Other Conditions Involving Cognitive Impairment by Papadopoulou, Paraskevi, Polissidis, Alexia, Kythreoti, Georgia, Sagnou, Marina, Stefanatou, Athena, Theoharides, Theoharis C

“…The European olive tree, L., and its polyphenols hold great therapeutic potential to treat neuroinflammation and cognitive impairment. This review examines the…”
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A novel curcumin gallium complex as photosensitizer in photodynamic therapy: Synthesis, structural and physicochemical characterization, photophysical properties and in vitro studies against breast cancer cells by Halevas, Eleftherios, Arvanitidou, Maria, Mavroidi, Barbara, Hatzidimitriou, Antonios G., Politopoulos, Konstantinos, Alexandratou, Eleni, Pelecanou, Maria, Sagnou, Marina

“…The synthesis, detailed structural and physicochemical characterization of a novel Ga(III)-curcumin complex with the ancillary aromatic chelator…”
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