Search Results - "Sagi, Sreedhar"

Cytotoxicity of cisplatin in bladder cancer is significantly enhanced by application of bcl-2 antisense oligonucleotides by Schaaf, Axel, Sagi, Sreedhar, Langbein, Sigrun, Trojan, Lutz, Alken, Peter, Michel, Maurice Stephan

“…Background: The aim of our study was to examine the effects of the combined application of cisplatin and bcl-2 antisense oligonucleotide on human bladder…”
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Long-Term Real-World Post-approval Safety Data of Multiple Biosimilars from One Marketing-Authorization Holder After More than 18 Years Since Their First Biosimilar Launch by Sagi, Sreedhar, Anjaneya, Pradeep, Kalsekar, Sameer, Kottke, Andrea, Cohen, Hillel P.

“…Background Biosimilars are additional treatment options that are approved based on robust analytical and clinical comparisons with their reference biologic. At…”
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Pharmacovigilance of Biologics in a Multisource Environment by Sagi, Sreedhar, Cohen, Hillel P, Woollett, Gillian R

“…It is important that systems are in place to ensure that appropriate and comprehensive records are kept for use of all medications. It is fundamental to an…”
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Evaluation of cystine transport in cultured human kidney cells and establishment of cystinuria type I phenotype by antisense technology by Wendt-Nordahl, Gunnar, Sagi, Sreedhar, Bolenz, Christian, Alken, Peter, Michel, Maurice Stephan, Knoll, Thomas

“…Cystinuria is a rare hereditary disease resulting in recurrent stone formation and the need for repeated invasive interventions. So far, two responsible genes…”
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Impact of hypoxia and hypercapnia on calcium oxalate toxicity in renal epithelial and interstitial cells by Cao, Yanwei, Sagi, Sreedhar, Häcker, Axel, Steidler, Annette, Alken, Peter, Knoll, Thomas

“…Although there is an ongoing controversy about the primary site of calcium oxalate stone (CaOx) formation, there is some evidence for extratubular…”
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221. A New Retroviral Gene Therapy Approach for Cystinuria Research by Sagi, Sreedhar, Picard-Maureau, Marcus, Dorries, Rudiger, Alken, Peter, Michel, Maurice S., Knoll, Thomas

“…Objectives: For cystinuria, gene therapy might provide a correction of the cellular dysfunction by expressing the deficient gene. Currently there is no stable…”
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959. bcl-2 Antisense Oligonucleotides Enhance the Cytotoxic Effects of Mitomycin C in the Treatment of Bladder Cancer by Schaaf, Axel, Sagi, Sreedhar, Langbein, Sigrun, Trojan, Lutz, Alken, Peter, Michel, Maurice S

“…IntroductionToxicity and the progressive resistance of conventional chemotherapeutic drugs are the main barriers of cancer chemotherapy in our times. The…”
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957. bcl-xL Antisense Oligonucleotides as an Enhancer of the Cytotoxic Effects of Cisplatin, Mitomycin C and Paclitaxel in the Treatment of Bladder Cancer by Schaaf, Axel, Sagi, Sreedhar, Langbein, Sigrun, Trojan, Lutz, Alken, Peter, Michel, Maurice S

“…IntroductionToxicity and the progressive resistance of conventional chemotherapeutic drugs are the main barriers of cancer chemotherapy in our times. The…”
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184. Evaluation of Cystine Transport in Cultured Human Kidney Cells: Primer to Gene Therapy of Cystinuria by Sagi, Sreedhar, Knoll, Thomas, Schaaf, Axel, Alken, Peter, Michel, Maurice Stephan

“…Introduction and objectives: For an efficient gene therapeutical approach, undperstanding the molecular basis of the disease is very important. Cystinuria is a…”
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The influence of oxalate on renal epithelial and interstitial cells by Knoll, Thomas, Steidler, Annette, Trojan, Lutz, Sagi, Sreedhar, Schaaf, Axel, Yard, Benito, Michel, Maurice Stephan, Alken, Peter

“…Most renal stones in humans are composed of calcium oxalate. An increase in urinary oxalate levels has been shown to result in renal epithelial cell injury and…”
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Impact of holmium:YAG and neodymium:YAG lasers on the efficacy of DNA delivery in transitional cell carcinoma by Knoll, Thomas, Trojan, Lutz, Langbein, Sigrun, Sagi, Sreedhar, Alken, Peter, Michel, Maurice Stephan

“…New approaches in the treatment of transitional cell carcinoma (TCC) are using gene therapy to influence the disease at the genetic level. Technical advances…”
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In vitro and ex vivo gene delivery into proximal tubular cells by means of laser energy--a potential approach for curing cystinuria? by Knoll, Thomas, Sagi, Sreedhar, Trojan, Lutz, Schaaf, Axel, Alken, Peter, Michel, Maurice Stephan

“…Cystinuria is the cause of 1-2% of stones observed in adults and about 10% of those occurring in children. Recurrent stone formation and multiple operations…”
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