Search Results - "Saghier, Ahmed M.M. El"

Utility of amino acid coupled 1,2,4-triazoles in organic synthesis: synthesis of some new antileishmainal agents by Saghier, Ahmed M.M. El, Mohamed, Mounir A.A, Abdalla, Omayma A, Kadry, Asmaa M

“…Starting from 3-amino-5-(2-hydroxyphenyl) amino acid coupled triazoles 1a-e, new 3-(2-hydroxyphenyl)-3H-imidazo[2,1-c][1,2,4]triazol-6(5/f)-one 2a,b, 3b,d, 6a…”
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The 13th IBN SINA International Conference on Pure and Applied Heterocyclic Chemistry (13th IbnSina; Hurghada, Egypt, February 14–17, 2015) by El-Saghier Ahmed M.M.

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Synthesis, characterization, molecular docking, and antimicrobial activities of some new sulfur containing norfloxacin analogues by El-Saghier, Ahmed M.M., Abosella, Laila, Elakesh, Esmail O., Abuo-Rahma, Gamal El-Din A., Abdou, Aly, Hamed, Amany M.

“…•Two new series of N-4 piperazinyl sulfur containing Ketene S,S-acetals and Ketene N,S-acetals, based norfloxacin analogues had been synthesized and…”
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Synthesis, DFT Calculations, Antiproliferative, Bactericidal Activity and Molecular Docking of Novel Mixed-Ligand Salen/8-Hydroxyquinoline Metal Complexes by Al-Farhan, Badriah Saad, Basha, Maram T., Abdel Rahman, Laila H., El-Saghier, Ahmed M. M., Abou El-Ezz, Doaa, Marzouk, Adel A., Shehata, Mohamed R., Abdalla, Ehab M.

“…Despite the common use of salens and hydroxyquinolines as therapeutic and bioactive agents, their metal complexes are still under development. Here, we report…”
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Thiazolidine-2,4-dione-linked ciprofloxacin derivatives with broad-spectrum antibacterial, MRSA and topoisomerase inhibitory activities by Aziz, Hossameldin A., El-Saghier, Ahmed M. M., Badr, Mohamed, Abuo-Rahma, Gamal El-Din A., Shoman, Mai E.

“…A series of ciprofloxacin/thiazolidine-2,4-dione hybrids 3a-m were prepared and identified by IR, 1 HNMR, 13 CNMR and elemental analysis. The antibacterial…”
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Synthesis and antidiabetic activity of novel triazole derivatives containing amino acids by Mohamed, Mounir A. A., Abd Allah, Omyma A., Bekhit, Adnan A., Kadry, Asmaa M., El‐Saghier, Ahmed M. M.

“…New series of triazole derivatives coupled with amino acids 1a‐h were obtained via multicomponent reaction of 2‐hydroxy benzaldehyde or 2‐hydroxy acetophenone…”
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Spiro heterocycles bearing piperidine moiety as potential scaffold for antileishmanial activity: synthesis, biological evaluation, and in silico studies by Mohamed, Mounir A. A., Kadry, Asmaa M., Bekhit, Salma A., Abourehab, Mohammed A. S., Amagase, Kikuko, Ibrahim, Tamer M., El-Saghier, Ahmed M. M., Bekhit, Adnan A.

“…New spiro-piperidine derivatives were synthesised via the eco-friendly ionic liquids in a one-pot fashion. The in vitro antileishmanial activity against…”
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Synthesis and antimicrobial activity of some novel 1,2-dihydro-[1,2,4]triazolo[1,5-]pyrimidines bearing amino acid moiety by Mohamed, Mounir A. A, Bekhit, Adnan A, Abd Allah, Omyma A, Kadry, Asmaa M, Ibrahim, Tamer M, Bekhit, Salma A, Amagase, Kikuko, El-Saghier, Ahmed M. M

“…A new series of [1,2,4]-triazole bearing amino acid derivatives 2a-d - 9a-d were synthesized under green chemistry conditions via multicomponent reaction using…”
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Insecticidal activity, and SAR studies of semicarbazide, thiosemicarbazide, urea and thiourea derivatives against Spodoptera littoralis (Boisd.) by Gad, Mohamed A., Alqurashi, Esam A., Alsenani, Nawaf I., Abd El Latif, Fawy M., Aref, Safwat A., Ahmed, N. A., Abdelhamid, Antar A., El-Saghier, Ahmed M. M.

“…Abstract In this article, series of semicarbazide, thiosemicarbazide, urea and thiourea derivatives have been successfully prepared via an easy synthetic…”
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Identification of a Novel DNA Gyrase Inhibitor via Design and Synthesis of New Antibacterial Pyrido[1′,2′:1,2]pyrimido[4,5‐e][1,3,4]thiadiazin‐5‐ol Derivatives by Khalil, Hosam H., Khattab, Sherine N., Toughan, Mayada M., El‐Saghier, Ahmed M. M., El‐Wakil, Marwa H.

“…Two new series of pyrido[1′,2′:1,2]pyrimido[4,5‐e][1,3,4]thiadiazin‐5‐ol Schiff's bases (4 a‐j) and 1,3,5‐triazinylaminobenzamides (6 a‐e) as effective…”
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Synthesis and antibacterial activity of some new fused chromenes by El-Saghier, Ahmed M. M., Naili, Mahbouba B., Rammash, Bahlul Kh, Saleh, Nabil A., Kreddan, Khaled M.

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A Simple Synthesis of Some New Thienopyridine and Thieno-pyrimidine Derivatives by El-Saghier, Ahmed M. M.

“…A number of pyridothienopyridine ( 2 , 3 ), pyridothienopyrimidine ( 6 , 10 ), pyridothienotriazine ( 13 ), pyrimidothienopyrimidine ( 15 , 16 , 17a,b ) and…”
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2,2′-[(1,3,4-Thiadiazole-2,5-diyl)bis(sulfanediyl)]diacetonitrile by Mague, Joel T., Akkurt, Mehmet, Mohamed, Shaaban K., El-Saghier, Ahmed M. M., Albayati, Mustafa R.

“…In the title compound, C 6 H 4 N 4 S 3 , the 1,3,4-thiadiazole ring is essentially planar, with an r.m.s. deviation of 0.001 Å. The two N—C—S—C torsion angles…”
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Synthesis and Reactions of Five-Membered Heterocycles Using Phase Transfer Catalyst (PTC) Techniques by Mohamed, Shaaban K., El-Saghier, Ahmed M. M., Abd Allah, Omyma A., El-Sayed, Ahmed M.

“…Phase transfer catalysts (PTCs) have been widely used for the synthesis of organic compounds particularly in both liquid-liquid and solid-liquid heterogeneous…”
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2-(4-Oxo-3-phenyl-1,3-thiazolidin-2-ylidene)propanedinitrile by Akkurt, Mehmet, El-Saghier, Ahmed M. M., Younes, Sabry H. H., Horton, Peter N., Albayati, Mustafa R.

“…In the title compound, C12H7N3OS, the five-membered 1,3-thiazolidine ring is nearly planar [maximum deviation = 0.032 (2) Å] and makes a dihedral angle of…”
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Ethyl 3-amino-5-anilino-4-cyanothiophene-2-carboxylate by El-Saghier, Ahmed M. M., Akkurt, Mehmet, Mohamed, Shaaban K., Horton, Peter N., Albayati, Mustafa R.

“…In the title compound, C14H13N3O2S, the dihedral angle between the thiophene and phenyl rings is 24.95 (8)°. The molecular structure is consolidated by…”
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1,4-Diazepines Bearing Thieno(2,3-b)Thiophene and Cyclohexene Carboxylate Moieties by El-Saghier, Ahmed M. M., Makhlouf, Mansour A., Farhat, Mahmoud F.

“…Bis[thieno(3,2-b)-1,4-diazepine] (4) and bis[imidazo(1′,2′)thieno(3,2-b)-1,4-diazepine (7) derivatives were prepared starting with thieno(2,3-b)thiophenes (1)…”
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A NOVEL SYNTHESIS OF SPIRO 1,3-DITHIIN AND SPIRO 1,3-THIAZINE DERIVATIVES UNDER PHASE TRANSFER CATALYSIS (PTC) CONDITIONS by El-Saghier, Ahmed M. M.

“…Ketene S,S-acetals 1a, b or ketene N,S-acetals 2a, b reacts in situ with a variety of ylidenemalononitriles to afford the desired spiro [1,3]dithiin…”
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A Novel One-Pot Synthesis of Polyfunctionally Substituted Thiopyrano(2,3- b )pyridine and Pyrido(2,3- b )pyridine Derivatives under Solid-Liquid Phase-Transfer Catalysis by El-Saghier, Ahmed M. M.

“…Ketoketene thioacetals or cyanoketene thioacetals which were formed by treatment of a variety of active methylenes containing f -keto or f -cyano group with CS…”
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SYNTHETIC REACTIONS OF COUMARIN-3-(4-AMINOSULFONYL)-CARBANILIDE DERIVATIVES WITH REACTIVE METHYLENE COMPOUNDS by El-saghier, Ahmed M.M., Al-afaleq, El-Jazi I.

“…Coumarin and benzo[f]coumarin-3-(4-aminosulfonyl)carbanilide derivatives 3a, b react with malononitrile or ethyl cyanoacetate to afford pyrido[3,4-c]- and…”
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