Search Results - "Sagher, Oren"

Variability in the location of high frequency oscillations during prolonged intracranial EEG recordings by Gliske, Stephen V., Irwin, Zachary T., Chestek, Cynthia, Hegeman, Garnett L., Brinkmann, Benjamin, Sagher, Oren, Garton, Hugh J. L., Worrell, Greg A., Stacey, William C.

“…The rate of interictal high frequency oscillations (HFOs) is a promising biomarker of the seizure onset zone, though little is known about its consistency over…”
Get full text

Pallidal versus Subthalamic Deep-Brain Stimulation for Parkinson's Disease by Follett, Kenneth A, Weaver, Frances M, Stern, Matthew, Hur, Kwan, Harris, Crystal L, Luo, Ping, Marks, William J, Rothlind, Johannes, Sagher, Oren, Moy, Claudia, Pahwa, Rajesh, Burchiel, Kim, Hogarth, Penelope, Lai, Eugene C, Duda, John E, Holloway, Kathryn, Samii, Ali, Horn, Stacy, Bronstein, Jeff M, Stoner, Gatana, Starr, Philip A, Simpson, Richard, Baltuch, Gordon, De Salles, Antonio, Huang, Grant D, Reda, Domenic J

“…In this randomized trial of deep-brain stimulation targeted to either the globus pallidus interna or the subthalamic nucleus in patients with advanced…”
Get full text

Rapid intraoperative histology of unprocessed surgical specimens via fibre-laser-based stimulated Raman scattering microscopy by Orringer, Daniel A., Pandian, Balaji, Niknafs, Yashar S., Hollon, Todd C., Boyle, Julianne, Lewis, Spencer, Garrard, Mia, Hervey-Jumper, Shawn L., Garton, Hugh J. L., Maher, Cormac O., Heth, Jason A., Sagher, Oren, Wilkinson, D. Andrew, Snuderl, Matija, Venneti, Sriram, Ramkissoon, Shakti H., McFadden, Kathryn A., Fisher-Hubbard, Amanda, Lieberman, Andrew P., Johnson, Timothy D., Xie, X. Sunney, Trautman, Jay K., Freudiger, Christian W., Camelo-Piragua, Sandra

“…Conventional methods for intraoperative histopathologic diagnosis are labour- and time-intensive, and may delay decision-making during brain-tumour surgery…”
Get full text

Hemoglobin and iron handling in brain after subarachnoid hemorrhage and the effect of deferoxamine on early brain injury by Lee, Jin-Yul, Keep, Richard F, He, Yangdong, Sagher, Oren, Hua, Ya, Xi, Guohua

“…The purpose of this study was to investigate hemoglobin and iron handling after subarachnoid hemorrhage (SAH), examine the relationship between iron and…”
Get full text

Development of a 3D-printed external ventricular drain placement simulator: technical note by Tai, Bruce L, Rooney, Deborah, Stephenson, Francesca, Liao, Peng-Siang, Sagher, Oren, Shih, Albert J, Savastano, Luis E

“…In this paper, the authors present a physical model developed to simulate accurate external ventricular drain (EVD) placement with realistic haptic and visual…”
Get full text

Comparison of experimental rat models of early brain injury after subarachnoid hemorrhage by Lee, Jin-Yul, Sagher, Oren, Keep, Richard, Hua, Ya, Xi, Guohua

“…To investigate acute pathophysiological changes after subarachnoid hemorrhage (SAH) in rats and compare endovascular perforation and double blood injection…”
Get full text

Assessment of wakefulness during awake craniotomy to predict intraoperative language performance by Aabedi, Alexander A, Ahn, EunSeon, Kakaizada, Sofia, Valdivia, Claudia, Young, Jacob S, Hervey-Jumper, Heather, Zhang, Eric, Sagher, Oren, Weissman, Daniel H, Brang, David, Hervey-Jumper, Shawn L

“…Maximal safe tumor resection in language areas of the brain relies on a patient's ability to perform intraoperative language tasks. Assessing the performance…”
Get full text

Subclonal evolution and expansion of spatially distinct THY1-positive cells is associated with recurrence in glioblastoma by Al-Holou, Wajd N., Wang, Hanxiao, Ravikumar, Visweswaran, Shankar, Sunita, Oneka, Morgan, Fehmi, Ziad, Verhaak, Roel GW, Kim, Hoon, Pratt, Drew, Camelo-Piragua, Sandra, Speers, Corey, Wahl, Daniel R, Hollon, Todd, Sagher, Oren, Heth, Jason A, Muraszko, Karin M., Lawrence, Theodore S., de Carvalho, Ana C, Mikkelsen, Tom, Rao, Arvind, Rehemtulla, Alnawaz

“…Glioblastoma(GBM) is a lethal disease characterized by inevitable recurrence. Here we investigate the molecular pathways mediating resistance, with the goal of…”
Get full text

Deep brain stimulation for refractory obsessive-compulsive disorder by Abelson, James L., Curtis, George C., Sagher, Oren, Albucher, Ronald C., Harrigan, Mark, Taylor, Stephan F., Martis, Brian, Giordani, Bruno

“…Neurosurgery (anterior capsulotomy) has been beneficial to many patients with debilitating, refractory obsessive-compulsive disorder (OCD), but the…”
Get full text

Advances in the Surgical Management of Low-Grade Glioma by Hollon, Todd, MD, Hervey-Jumper, Shawn L., MD, Sagher, Oren, MD, Orringer, Daniel A., MD

“…Over the past 2 decades, extent of resection has emerged as a significant prognostic factor in patients with low-grade gliomas (LGGs). Greater extent of…”
Get full text

Defining Glioblastoma Resectability Through the Wisdom of the Crowd: A Proof-of-Principle Study by Sonabend, Adam M., Zacharia, Brad E., Cloney, Michael B., Sonabend, Aarón, Showers, Christopher, Ebiana, Victoria, Nazarian, Matthew, Swanson, Kristin R., Baldock, Anne, Brem, Henry, Bruce, Jeffrey N., Butler, William, Cahill, Daniel P., Carter, Bob, Orringer, Daniel A., Roberts, David W., Sagher, Oren, Sanai, Nader, Schwartz, Theodore H., Silbergeld, Daniel L., Sisti, Michael B., Thompson, Reid C., Waziri, Allen E., McKhann, Guy

“…Abstract BACKGROUND: Extent of resection (EOR) correlates with glioblastoma outcomes. Resectability and EOR depend on anatomical, clinical, and surgeon…”
Get full text

Methylene Blue-Conjugated Hydrogel Nanoparticles and Tumor-Cell Targeted Photodynamic Therapy by Hah, Hoe Jin, Kim, Gwangseong, Lee, Yong-Eun Koo, Orringer, Daniel A., Sagher, Oren, Philbert, Martin A., Kopelman, Raoul

“…Methylene blue‐conjugated polyacrylamide nanoparticles are prepared through a microemulsion polymerization, after conjugation of the dye with a monomer. The…”
Get full text

Simulator and 2 tools: Validation of performance measures from a novel neurosurgery simulation model using the current Standards framework by Rooney, Deborah M., PhD, Tai, Bruce L., PhD, Sagher, Oren, MD, Shih, Albert J., PhD, Wilkinson, David Andrew, MD, Savastano, Luis E., MD

“…Background Ventriculostomy is a common neurosurgical procedure with a relatively steep learning curve. A low-cost, high-fidelity simulator paired with…”
Get full text

Effects of Vagus Nerve Stimulation on Sleep‐related Breathing in Epilepsy Patients by Marzec, Mary, Edwards, Jonathan, Sagher, Oren, Fromes, Gail, Malow, Beth A.

“…Purpose: To describe the effects of vagus nerve stimulation (VNS) on sleep‐related breathing in a sample of 16 epilepsy patients. Methods: Sixteen adults with…”
Get full text

Gemcitabine Plus Radiation Therapy for High-Grade Glioma: Long-Term Results of a Phase 1 Dose-Escalation Study by Kim, Michelle M., MD, Camelo-Piragua, Sandra, MD, Schipper, Matthew, PhD, Tao, Yebin, MS, Normolle, Daniel, PhD, Junck, Larry, MD, Mammoser, Aaron, MD, Betz, Bryan L., PhD, Cao, Yue, PhD, Kim, Christopher J., BA, Heth, Jason, MD, Sagher, Oren, MD, Lawrence, Theodore S., MD, PhD, Tsien, Christina I., MD

“…Purpose To evaluate the tolerability and efficacy of gemcitabine plus radiation therapy (RT) in this phase 1 study of patients with newly diagnosed malignant…”
Get full text

Do electronic health records help or hinder medical education? by Peled, Jonathan U, Sagher, Oren, Morrow, Jay B, Dobbie, Alison E

“…Many countries worldwide are digitizing patients' medical records. What impact will these electronic health records have upon medical education? This debate…”
Get full text

Targeted Blue Nanoparticles as Photoacoustic Contrast Agent for Brain Tumor Delineation by Ray, Aniruddha, Wang, Xueding, Lee, Yong-Eun Koo, Hah, Hoe Jin, Kim, Gwangseong, Chen, Thomas, Orringer, Daniel A., Sagher, Oren, Liu, Xiaojun, Kopelman, Raoul

“…Distinguishing a tumor from non-neoplastic tissue is a challenging task during cancer surgery. Several attempts have been made to use visible or fluorescent…”
Get full text

Characterization of an improved double hemorrhage rat model for the study of delayed cerebral vasospasm by Lee, Jin-Yul, Huang, Dah-Luen, Keep, Richard, Sagher, Oren

“…Rats have been shown in several studies to develop delayed cerebral vasospasm after subarachnoid hemorrhage (SAH). However, the rat model has not yet been…”
Get full text

Mechanisms of edema formation after intracerebral hemorrhage : effects of thrombin on cerebral blood flow, blood-brain barrier permeability, and cell survival in a rat model by LEE, K. R, KAWAI, N, KIM, S, SAGHER, O, HOFF, J. T

“…Recently, the authors showed that thrombin contributes to the formation of brain edema following intracerebral hemorrhage. The current study examines whether…”
Get full text

Irreversible Spinal Nerve Injury From Dorsal Ramus Radiofrequency Neurotomy: A Case Report by Abbott, Zachary, DO, Smuck, Matthew, MD, Haig, Andrew, MD, Sagher, Oren, MD

“…Abstract Abbott Z, Smuck M, Haig A, Sagher O. Irreversible spinal nerve injury from dorsal ramus radiofrequency neurotomy: a case report. Radiofrequency…”
Get full text