Search Results - "Saggar, R."

Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension by Moriarty, J. M., Khan, S. N., Kao, S. D., Saggar, R.

“…Chronic thromboembolic pulmonary hypertension (CTEPH) is a potentially lethal outcome of pulmonary embolism. Balloon pulmonary angioplasty (BPA) is aimed at…”
Get full text

The Role of TGF-[beta] in the Association Between Primary Graft Dysfunction and Bronchiolitis Obliterans Syndrome by DerHovanessian, A, Weigt, S S, Palchevskiy, V, Shino, M Y, Sayah, D M, Gregson, A L, Noble, P W, Palmer, S M, Fishbein, M C, Kubak, B M, Ardehali, A, Ross, D J, Saggar, R, Lynch, J P, Elashoff, R M, Belperio, J A

“…Primary graft dysfunction (PGD) is a possible risk factor for bronchiolitis obliterans syndrome (BOS) following lung transplantation; however, the mechanism…”
Get full text

Colonization With Small Conidia Aspergillus Species Is Associated With Bronchiolitis Obliterans Syndrome: A Two‐Center Validation Study by Weigt, S. S., Copeland, C. A. Finlen, Derhovanessian, A., Shino, M. Y., Davis, W. A., Snyder, L. D., Gregson, A. L., Saggar, R., Lynch, J. P., Ross, D. J., Ardehali, A., Elashoff, R. M., Palmer, S. M., Belperio, J. A.

“…Aspergillus colonization after lung transplantation may increase the risk for bronchiolitis obliterans syndrome (BOS), a disease of small airways. We…”
Get full text

The Role of TGF-β in the Association Between Primary Graft Dysfunction and Bronchiolitis Obliterans Syndrome by DerHovanessian, A., Weigt, S.S., Palchevskiy, V., Shino, M.Y., Sayah, D.M., Gregson, A.L., Noble, P.W., Palmer, S.M., Fishbein, M.C., Kubak, B.M., Ardehali, A., Ross, D.J., Saggar, R., Lynch, J.P., Elashoff, R.M., Belperio, J.A.

“…Primary graft dysfunction (PGD) is a possible risk factor for bronchiolitis obliterans syndrome (BOS) following lung transplantation; however, the mechanism…”
Get full text

The Prognostic Importance of Bronchoalveolar Lavage Fluid CXCL9 During Minimal Acute Rejection on the Risk of Chronic Lung Allograft Dysfunction by Shino, M. Y., Weigt, S. S., Li, N., Derhovanessian, A., Sayah, D. M., Saggar, R., Huynh, R. H., Gregson, A. L., Ardehali, A., Ross, D. J., Lynch, J. P., Elashoff, R. M., Belperio, J. A.

“…The clinical significance and treatment strategies for minimal acute rejection (grade A1), the most common form of acute rejection (AR), remain controversial…”
Get full text

Aspergillus Colonization of the Lung Allograft Is a Risk Factor for Bronchiolitis Obliterans Syndrome by Weigt, S. S., Elashoff, R. M., Huang, C., Ardehali, A., Gregson, A. L., Kubak, B., Fishbein, M. C., Saggar, R., Keane, M. P., Saggar, R., Lynch III, J. P., Zisman, D. A., Ross, D. J., Belperio, J. A.

“…Multiple infections have been linked with the development of bronchiolitis obliterans syndrome (BOS) post‐lung transplantation. Lung allograft airway…”
Get full text

Fungal Prophylaxis and Chronic Lung Allograft Dysfunction by Beach, S.L., Schaenman, J.M., Shino, Y.M., Ramsey, A., Saggar, R., Sayah, D.M., DerHovanessian, A., III, J.P. Lynch, Ardehali, A., Belperio, J.A., Weigt, S.S.

“…Prior studies demonstrate that lung transplant recipients (LTRs) experience the highest rate of invasive mold infections amongst all transplant recipients…”
Get full text

Combination treatment with omalizumab and rush immunotherapy for ragweed-induced allergic rhinitis: Inhibition of IgE-facilitated allergen binding by Klunker, Sven, PhD, Saggar, Lavina R., MSc, Seyfert-Margolis, Vicki, PhD, Asare, Adam L., PhD, Casale, Thomas B., MD, Durham, Stephen R., MD, Francis, James N., PhD

“…Background The combination of anti-IgE (omalizumab) therapy with ragweed injection immunotherapy for seasonal allergic rhinitis results in a significant…”
Get full text

Systemic sclerosis and bilateral lung transplantation: a single centre experience by SAGGAR, R, KHANNA, D, SHAPIRO, S, HUNTER, C, GREGSON, A, FISHBEIN, M. C, LYNCH, J. P, ROSS, D. J, FURST, D. E, BELPERIO, J. A, PARK, G. S, WEIGT, S. S, KUBAK, B, ARDEHALI, A, DERHOVANESSIAN, A, CLEMENTS, P. J

“…Lung involvement is the leading cause of death in systemic sclerosis (SSc), but lung transplantation (LT) for systemic disease remains controversial. Our…”
Get full text

Impact of Allograft Injury Time of Onset on the Development of Chronic Lung Allograft Dysfunction After Lung Transplantation by Shino, M. Y., Weigt, S. S., Li, N., Derhovanessian, A., Sayah, D. M., Huynh, R. H., Saggar, R., Gregson, A. L., Ardehali, A., Ross, D. J., Lynch, J. P., Elashoff, R. M., Belperio, J. A.

“…The impact of allograft injury time of onset on the risk of chronic lung allograft dysfunction (CLAD) remains unknown. We hypothesized that episodes of…”
Get full text

Periostitis Secondary to Prolonged Voriconazole Therapy in Lung Transplant Recipients by Wang, T. F., Wang, T., Altman, R., Eshaghian, P., Lynch, J. P., Ross, D. J., Belperio, J. A., Weigt, S. S., Saggar, R., Gregson, A., Kubak, B., Saggar, R.

“…We report five cases of possible drug‐induced periostitis associated with long‐term use of voriconazole therapy after lung transplantation (LT). The diagnosis…”
Get full text

Pulmonary vascular responses to exercise: a haemodynamic observation by Saggar, R, Lewis, G D, Systrom, D M, Champion, H C, Naeije, R

Get full text

Effects of Parenteral Treprostinil on Functional Capacity, Hemodynamics, and Right Heart Function in Patients Referred to LTx with Pulmonary Fibrosis & Significant PH by Saggar, R, Fields, A, Khanna, D, Paul, F

“…Purpose The use of pulmonary hypertension (PH) specific therapy in the setting of pulmonary fibrosis (PF) is controversial. Determine the effects of chronic…”
Get full text

Staphylococcus via an Interaction With the ELR+ CXC Chemokine ENA‐78 Is Associated With BOS by Gregson, A. L., Wang, X., Injean, P., Weigt, S. S., Shino, M., Sayah, D., DerHovanessian, A., Lynch, J. P., Ross, D. J., Saggar, R., Ardehali, A., Li, G., Elashoff, R., Belperio, J. A.

“…Staphylococcus aureus is the most commonly isolated gram‐positive bacterium after lung transplantation (LT) and has been associated with poor posttransplant…”
Get full text

Prevalence of Forgut Dysfunction in Pulmonary Fibrosis and COPD Patients Undergoing LTx Evaluation by Hooft, N, Saggar, R, Smith, M, Kuo, E, Huang, J, Walia, R, Bremner, R

Get full text

Viral Pneumonia Accelerates Graft Death and CLAD in Lung Transplant Recipients by Allyn, P.R, Duffy, E.L, Humphries, R.M, Saggar, R, Weight, S.S, Belperio, J.A, Tseng, C, Gregson, A.L

Get full text

614 Simple Echo-Doppler Tool Powerfully Predicts Response to Pulmonary Hypertension Specific Therapy in WHO Group 3 Pulmonary Hypertension by Fields, A.V, Sinha, S.S, Saggar, R, Forfia, P.R

Get full text

Gene Expression Profiling of Bronchoalveolar Lavage Cells during Aspergillus Colonization of the Lung Allograft by Weigt, S.S, Wang, X, Palchevskiy, V, Patel, N, DerHovanessian, A, Shino, M.Y, Sayah, D, Gregson, A.L, Lynch III, J.P, Saggar, R, Ross, D.J, Ardehali, A, Elashoff, D, Belperio, J.A

Get full text

CXCR3 Chemokine Ligands During Respiratory Viral Infections Predict Lung Allograft Dysfunction by Weigt, S. S., Derhovanessian, A., Liao, E., Hu, S., Gregson, A. L., Kubak, B. M., Saggar, R., Saggar, R., Plachevskiy, V., Fishbein, M. C., Lynch, J. P., Ardehali, A., Ross, D. J., Wang, H.‐J., Elashoff, R. M., Belperio, J. A.

“…Community‐acquired respiratory viruses (CARV) can accelerate the development of lung allograft dysfunction, but the immunologic mechanisms are poorly…”
Get full text

Altered Levels of CC Chemokines During Pulmonary CMV Predict BOS and Mortality Post‐Lung Transplantation by Weigt, S. S., Elashoff, R. M., Keane, M. P., Strieter, R. M., Gomperts, B. N., Xue, Y. Y., Ardehali, A., Gregson, A. L., Kubak, B., Fishbein, M. C., Saggar, R., Ross, D. J., Lynch III, J. P., Zisman, D. A., Belperio, J. A.

“…Pulmonary CMV infection (CMVI) and disease (CMVD) is associated with reduced long‐term survival post‐lung transplantation, however, the specific biologic…”
Get full text