Search Results - "Sageshima, Noriko"

Persimmon-derived tannin ameliorates the pathogenesis of ulcerative colitis in a murine model through inhibition of the inflammatory response and alteration of microbiota by Kitabatake, Masahiro, Matsumura, Yoko, Ouji-Sageshima, Noriko, Nishioka, Tatsuki, Hara, Atsushi, Kayano, Shin-ichi, Ito, Toshihiro

“…Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) induced by dysregulation of the immune response in the intestinal mucosa. Although the…”
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Persimmon-derived tannin has antiviral effects and reduces the severity of infection and transmission of SARS-CoV-2 in a Syrian hamster model by Furukawa, Ryutaro, Kitabatake, Masahiro, Ouji-Sageshima, Noriko, Suzuki, Yuki, Nakano, Akiyo, Matsumura, Yoko, Nakano, Ryuichi, Kasahara, Kei, Kubo, Kaoru, Kayano, Shin-ichi, Yano, Hisakazu, Ito, Toshihiro

“…Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread across the world. Inactivating…”
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Transition of Antibody Titers after SARS-CoV-2 mRNA Vaccination in Japanese Healthcare Workers by Kitabatake, Masahiro, Ouji-Sageshima, Noriko, Sonobe, Shota, Furukawa, Ryutaro, Konda, Makiko, Hara, Atsushi, Aoki, Hiroyasu, Suzuki, Yuki, Imakita, Natsuko, Nakano, Akiyo, Fujita, Yukio, Shichino, Shigeyuki, Nakano, Ryuichi, Ueha, Satoshi, Kasahara, Kei, Muro, Shigeo, Yano, Hisakazu, Matsushima, Kouji, Ito, Toshihiro

“…Since February 2021, healthcare workers in Japan have been preferentially vaccinated with a messenger RNA vaccine (BNT162b2; Pfizer/BioNTech) against severe…”
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Abrogated Caveolin-1 expression via histone modification enzyme Setdb2 regulates brain edema in a mouse model of influenza-associated encephalopathy by Imakita, Natsuko, Kitabatake, Masahiro, Ouji-Sageshima, Noriko, Hara, Atsushi, Morita-Takemura, Shoko, Kasahara, Kei, Matsukawa, Akihiro, Wanaka, Akio, Mikasa, Keiichi, Ito, Toshihiro

“…Influenza-associated encephalopathy (IAE) is a serious complication that can follow influenza virus infection. Once a cytokine storm is induced during…”
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Transition of antibody titers after the SARS-CoV-2 mRNA vaccine in Japanese healthcare workers by Kitabatake, Masahiro, Ouji-Sageshima, Noriko, Sonobe, Shota, Furukawa, Ryutaro, Konda, Makiko, Hara, Atsushi, Aoki, Hiroyasu, Suzuki, Yuki, Imakita, Natsuko, Nakano, Akiyo, Fujita, Yukio, Shichino, Shigeyuki, Nakano, Ryuichi, Ueha, Satoshi, Kasahara, Kei, Muro, Shigeo, Yano, Hisakazu, Matsushima, Kouji, Ito, Toshihiro

“…Since February 2021, healthcare workers in Japan have been preferentially vaccinated with a messenger RNA vaccine (BNT162b2/Pfizer) against severe acute…”
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Osteogenesis of osteogenic matrix cell sheets preserved in culture medium in a rat model by Kira, Tsutomu, Akahane, Manabu, Ouji-Sageshima, Noriko, Shimizu, Takamasa, Onishi, Tadanobu, Omokawa, Shohei, Ito, Toshihiro, Tanaka, Yasuhito

“…Osteogenic matrix cell sheets (OMCSs) are ideal for bone regeneration. Transportation of OMCSs may be necessary, during which their osteogenic ability must be…”
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Protein Expression and Peptide Binding Suggest Unique and Interacting Functional Roles for HLA-E, F, and G in Maternal-Placental Immune Recognition by Ishitani, Akiko, Sageshima, Noriko, Lee, Ni, Dorofeeva, Natalia, Hatake, Katsuhiko, Marquardt, Hans, Geraghty, Daniel E

“…In this study we focused on the structure and expression of the HLA-E, F, and G class I complexes in placental tissue. Structural analysis included an…”
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Maternal supplementation with Bifidobacterium breve M-16V prevents their offspring from allergic airway inflammation accelerated by the prenatal exposure to an air pollutant aerosol by Terada-Ikeda, Chiyoko, Kitabatake, Masahiro, Hiraku, Akari, Kato, Kumiko, Yasui, Satsuki, Imakita, Natsuko, Ouji-Sageshima, Noriko, Iwabuchi, Noriyuki, Hamada, Kaoru, Ito, Toshihiro, Fehrenbach, Heinz

“…Bifidobacterium breve M-16V is a probiotic bacterial strain with efficacy in infants achieved by suppressing T-helper type (Th) 2 immune responses and…”
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Angiopoietin-like 4 is a critical regulator of fibroblasts during pulmonary fibrosis development by Saito, Shoichiro, Kitabatake, Masahiro, Ouji-Sageshima, Noriko, Ogawa, Tatsuro, Oda, Akihisa, Nishimura, Tomoko, Nishioka, Tatsuki, Fushimi, Satoki, Hara, Atsushi, Shichino, Shigeyuki, Kumamoto, Makiko, Hontsu, Shigeto, Kawaguchi, Takeshi, Ueha, Satoshi, Sawabata, Noriyoshi, Muro, Shigeo, Matsushima, Kouji, Ito, Toshihiro

“…Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible interstitial pneumonia caused by the excessive production and deposition of…”
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The spleen is the major site for the development and expansion of inhibitor producing-cells in hemophilia A mice upon FVIII infusion developing high-titer inhibitor by Oda, Akihisa, Furukawa, Shoko, Kitabatake, Masahiro, Ouji-sageshima, Noriko, Sonobe, Shota, Horiuchi, Kaoru, Nakajima, Yuto, Ogiwara, Kenichi, Goitsuka, Ryo, Shima, Midori, Ito, Toshihiro, Nogami, Keiji

“…Hemophilia A (HA) is a hereditary bleeding disorder caused by defects in endogenous factor (F)VIII. Approximately 30 % of patients with severe HA treated with…”
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A Disintegrin and Metalloproteinase with Thrombospondin Motifs 4 Regulates Pulmonary Vascular Hyperpermeability through Destruction of Glycocalyx in Acute Respiratory Distress Syndrome by Konda, Makiko, Kitabatake, Masahiro, Ouji-Sageshima, Noriko, Tonomura, Rei, Furukawa, Ryutaro, Sonobe, Shota, Terada-Ikeda, Chiyoko, Takeda, Maiko, Kawaguchi, Masahiko, Ito, Toshihiro

“…Acute respiratory distress syndrome (ARDS) has no specific and effective treatment, and there is an urgent need to understand its pathogenesis. Therefore,…”
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Verification of A New Filter for Isolation of Circulating Tumor Cells by Only Blood Filtration by Morita, Kohei, Sawabata, Noriyoshi, Tatsumi, Shigenobu, Fujii, Tomomi, Nishikawa, Takashi, Kawaguchi, Takeshi, Arakane, Toru, Tominaga, Yoshiaki, Sakaguchi, Hirokazu, Kobayashi, Taro, Hontsu, Shigeto, Yamamoto, Yoshifumi, Fujioka, Nobuhiro, Ouji-Sageshima, Noriko, Ito, Toshihiro, Ohbayashi, Chiho

“…Background/Aim: Since circulating tumor cells (CTCs) are precursors of metastatic lesions, extracting CTCs from whole blood is useful in obtaining information…”
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Pure Solid Pattern of Non-Small Cell Lung Cancer and Clustered Circulating Tumor Cells by Sawabata, Noriyoshi, Kawaguchi, Takeshi, Watanabe, Takashi, Yohikawa, Daiki, Ouji-Sageshima, Noriko, Ito, Toshihiro

“…There are two solid patterns of non-small cell lung cancer (NSCLC) on computed tomography (CT): pure or mixed with ground-glass opacities (GGOs). They predict…”
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Persimmon-derived tannin has bacteriostatic and anti-inflammatory activity in a murine model of Mycobacterium avium complex (MAC) disease by Matsumura, Yoko, Kitabatake, Masahiro, Ouji-Sageshima, Noriko, Yasui, Satsuki, Mochida, Naoko, Nakano, Ryuichi, Kasahara, Kei, Tomoda, Koichi, Yano, Hisakazu, Kayano, Shin-Ichi, Ito, Toshihiro

“…Nontuberculous mycobacteria (NTM), including Mycobacterium avium complex (MAC), cause opportunistic chronic pulmonary infections. Notably, MAC susceptibility…”
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Lipopolysaccharide from Yoshino cedar trees (Cryptomeria japonica) induces high levels of human macrophage polarization by Ouji-Sageshima, Noriko, Kitabatake, Masahiro, Fushimi, Satoki, Suzuki, Satoshi, Fukui, Yuzu, Furukawa, Ryutaro, Ito, Toshihiro

“…Japanese cedar, Cryptomeria japonica, is an evergreen conifer native to Japan and is often used as a building material. The humidity control properties of wood…”
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Antiviral Effect of Candies Containing Persimmon-Derived Tannin against SARS-CoV-2 Delta Strain by Furukawa, Ryutaro, Kitabatake, Masahiro, Ouji-Sageshima, Noriko, Tomita, Dai, Kumamoto, Makiko, Suzuki, Yuki, Nakano, Akiyo, Nakano, Ryuichi, Matsumura, Yoko, Kayano, Shin-ichi, Yano, Hisakazu, Tamaki, Shinji, Ito, Toshihiro

“…Inactivation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the mouth has the potential to reduce the spread of coronavirus disease 2019…”
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Oral SARS-CoV-2 Inoculation Causes Nasal Viral Infection Leading to Olfactory Bulb Infection: An Experimental Study by Ueha, Rumi, Ito, Toshihiro, Furukawa, Ryutaro, Kitabatake, Masahiro, Ouji-Sageshima, Noriko, Ueha, Satoshi, Koyama, Misaki, Uranaka, Tsukasa, Kondo, Kenji, Yamasoba, Tatsuya

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections can cause long-lasting anosmia, but the impact of SARS-CoV-2 infection, which can…”
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TAS-Seq is a robust and sensitive amplification method for bead-based scRNA-seq by Shichino, Shigeyuki, Ueha, Satoshi, Hashimoto, Shinichi, Ogawa, Tatsuro, Aoki, Hiroyasu, Wu, Bin, Chen, Chang-Yu, Kitabatake, Masahiro, Ouji-Sageshima, Noriko, Sawabata, Noriyoshi, Kawaguchi, Takeshi, Okayama, Toshitugu, Sugihara, Eiji, Hontsu, Shigeto, Ito, Toshihiro, Iwata, Yasunori, Wada, Takashi, Ikeo, Kazuho, Sato, Taka-Aki, Matsushima, Kouji

“…Single-cell RNA-sequencing (scRNA-seq) is valuable for analyzing cellular heterogeneity. Cell composition accuracy is critical for analyzing cell–cell…”
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Evidence for the spread of SARS-CoV-2 and olfactory cell lineage impairment in close-contact infection Syrian hamster models by Ueha, Rumi, Ito, Toshihiro, Ueha, Satoshi, Furukawa, Ryutaro, Kitabatake, Masahiro, Ouji-Sageshima, Noriko, Uranaka, Tsukasa, Tanaka, Hirotaka, Nishijima, Hironobu, Kondo, Kenji, Yamasoba, Tatsuya

“…ObjectivesClose contact with patients with COVID-19 is speculated to be the most common cause of viral transmission, but the pathogenesis of COVID-19 by close…”
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Recombinant RSV G protein vaccine induces enhanced respiratory disease via IL-13 and mucin overproduction by Kawahara, Eigo, Senpuku, Kota, Kawaguchi, Yoshino, Yamamoto, Shinya, Yasuda, Koubun, Kuroda, Etsushi, Ouji-Sageshima, Noriko, Ito, Toshihiro, Hirai, Toshiro, Shibata, Takehiko, Yoshioka, Yasuo

“…The G protein expressed on the surface of respiratory syncytial virus (RSV) is important for adhesion to host cells and as a vaccine target antigen. The…”
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