Search Results - "Sagert, Jason G"

CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma by Choi, Bryan D., Yu, Xiaoling, Castano, Ana P., Darr, Henia, Henderson, Daniel B., Bouffard, Amanda A., Larson, Rebecca C., Scarfò, Irene, Bailey, Stefanie R., Gerhard, Genevieve M., Frigault, Matthew J., Leick, Mark B., Schmidts, Andrea, Sagert, Jason G., Curry, William T., Carter, Bob S., Maus, Marcela V.

“…Despite remarkable success in the treatment of hematological malignancies, CAR T-cell therapies for solid tumors have floundered, in large part due to local…”
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Tumor-specific activation of an EGFR-targeting probody enhances therapeutic index by Desnoyers, Luc R, Vasiljeva, Olga, Richardson, Jennifer H, Yang, Annie, Menendez, Elizabeth E M, Liang, Tony W, Wong, Chihunt, Bessette, Paul H, Kamath, Kathy, Moore, Stephen J, Sagert, Jason G, Hostetter, Daniel R, Han, Fei, Gee, Jason, Flandez, Jeanne, Markham, Kate, Nguyen, Margaret, Krimm, Michael, Wong, Kenneth R, Liu, Shouchun, Daugherty, Patrick S, West, James W, Lowman, Henry B

“…Target-mediated toxicity constitutes a major limitation for the development of therapeutic antibodies. To redirect the activity of antibodies recognizing…”
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A leucine-rich repeat region is conserved in pollen extensin-like (Pex) proteins in monocots and dicots by Stratford, S, Barne, W, Hohorst, D L, Sagert, J G, Cotter, R, Golubiewski, A, Showalter, A M, McCormick, S, Bedinger, P

“…We previously isolated a pollen-specific gene encoding a pollen tube wall-associated glycoprotein with a globular domain and an extensin domain from maize…”
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