Search Results - "Sagami, Ikuko"

Circadian clock disruption by selective removal of endogenous carbon monoxide by Minegishi, Saika, Sagami, Ikuko, Negi, Shigeru, Kano, Koji, Kitagishi, Hiroaki

“…Circadian rhythms are regulated by transcription-translation feedback loops (TTFL) of clock genes. Previous studies have demonstrated that core transcriptional…”
Get full text

Changes in pH and NADPH Regulate the DNA Binding Activity of Neuronal PAS Domain Protein 2, a Mammalian Circadian Transcription Factor by Yoshii, Katsuhiro, Tajima, Fumihisa, Ishijima, Sumio, Sagami, Ikuko

“…Neuronal PAS domain protein 2 (NPAS2) is a core clock transcription factor that forms a heterodimer with BMAL1 to bind the E-box in the promoter of clock genes…”
Get full text

The homologous Arabidopsis MRS2/MGT/CorA-type Mg2+ channels, AtMRS2-10 and AtMRS2-1 exhibit different aluminum transport activity by Ishijima, Sumio, Manabe, Yuri, Shinkawa, Yuri, Hotta, Ayumi, Tokumasu, Akino, Ida, Moe, Sagami, Ikuko

“…Magnesium (Mg2+) plays a critical role in many physiological processes. The AtMRS2/MGT family, which consists of nine Arabidopsis genes (and two pseudo-genes)…”
Get full text

Thermodynamic Characterization of the Ca2+-Dependent Interaction Between SOUL and ALG-2 by Mikasa, Taisuke, Kugo, Masami, Nishimura, Seigo, Taketani, Sigeru, Ishijima, Sumio, Sagami, Ikuko

“…SOUL, a heme-binding protein-2 (HEBP-2), interacts with apoptosis-linked gene 2 protein (ALG-2) in a Ca2+-dependent manner. To investigate the properties of…”
Get full text

Magnesium uptake of Arabidopsis transporters, AtMRS2-10 and AtMRS2-11, expressed in Escherichia coli mutants: Complementation and growth inhibition by aluminum by Ishijima, Sumio, Uda, Misaki, Hirata, Tomohiro, Shibata, Makiko, Kitagawa, Nozomi, Sagami, Ikuko

“…Magnesium (Mg2+) plays a critical role in many physiological processes. Mg2+ transport systems in Salmonella have been well documented, but those in…”
Get full text

Functional reconstitution and characterization of the Arabidopsis Mg2+ transporter AtMRS2-10 in proteoliposomes by Ishijima, Sumio, Shigemi, Zenpei, Adachi, Hiroaki, Makinouchi, Nana, Sagami, Ikuko

“…Magnesium (Mg2+) plays critical role in many physiological processes. The mechanism of Mg2+ transport has been well documented in bacteria; however, less is…”
Get full text

Effects of the bHLH domain on axial coordination of heme in the PAS-A domain of neuronal PAS domain protein 2 (NPAS2): Conversion from His119/Cys170 coordination to His119/His171 coordination by Uchida, Takeshi, Sagami, Ikuko, Shimizu, Toru, Ishimori, Koichiro, Kitagawa, Teizo

“…Neuronal PAS domain protein 2 (NPAS2), which is a CO-dependent transcription factor, consists of a basic helix–loop–helix domain (bHLH), and two…”
Get full text

A Redox-controlled Molecular Switch Revealed by the Crystal Structure of a Bacterial Heme PAS Sensor by Kurokawa, Hirofumi, Lee, Dong-Sun, Watanabe, Miki, Sagami, Ikuko, Mikami, Bunzo, Raman, C S, Shimizu, Toru

“…PAS domains, which have been identified in over 1100 proteins from all three kingdoms of life, convert various input stimuli into signals that propagate to…”
Get full text

Thermodynamic Analysis of Interactions between Cofactor and Neuronal Nitric Oxide Synthase by Sanae, Ryuhei, Kurokawa, Fumiaki, Oda, Masayuki, Ishijima, Sumio, Sagami, Ikuko

“…The thermodynamics of cofactor binding to the isolated reductase domain (Red) of nNOS and its mutants have been studied by isothermal titration calorimetry…”
Get full text

CO-dependent Activity-controlling Mechanism of Heme-containing CO-sensor Protein, Neuronal PAS Domain Protein 2 by Uchida, Takeshi, Sato, Emiko, Sato, Akira, Sagami, Ikuko, Shimizu, Toru, Kitagawa, Teizo

“…Neuronal PAS domain protein 2, which was recently established to be a heme protein, acts as a CO-dependent transcription factor. The protein consists of the…”
Get full text

Imaging of heme/hemeproteins in nucleus of the living cells expressing heme-binding nuclear receptors by Itoh, Ryuhei, Fujita, Ken-ichi, Mu, Anfeng, Kim, Dao Hoang Thien, Tai, Tran Tien, Sagami, Ikuko, Taketani, Shigeru

“…•Fluorescence from DCFH-DA was observed in hemeprotein-expressing cells.•We examined heme-binding of transcriptional factors, NPAS2 and REV-erbα in vivo.•DCF…”
Get full text

Effects of mutations in the heme domain on the transcriptional activity and DNA-binding activity of NPAS2 by Ishida, Mashiho, Ueha, Takeshi, Sagami, Ikuko

“…The heme domain of neuronal PAS domain protein 2 (NPAS2), a transcription factor that regulates the mammalian circadian rhythm, has been suggested to act as a…”
Get full text

The 42-Amino Acid Insert in the FMN Domain of Neuronal Nitric-oxide Synthase Exerts Control over Ca2+/Calmodulin-dependent Electron Transfer by Daff, Simon, Sagami, Ikuko, Shimizu, Toru

“…The neuronal and endothelial nitric-oxide synthases (nNOS and eNOS) differ from inducible NOS in their dependence on the intracellular Ca2+ concentration. Both…”
Get full text

DOSEc, a Heme-Regulated Phosphodiesterase, Plays an Important Role in the Regulation of the Cyclic AMP Level in Escherichia coli by YOSHIMURA-SUZUKI, Tokiko, SAGAMI, Ikuko, YOKOTA, Nao, KUROKAWA, Hirofumi, SHIMIZU, Toru

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Functional analysis of whether the glycine residue of the GMN motif of the Arabidopsis MRS2/MGT/CorA-type Mg2+ channel protein AtMRS2-11 is critical for Mg2+ transport activity by Ishijima, Sumio, Shiomi, Rikako, Sagami, Ikuko

“…Magnesium (Mg2+) plays a critical role in many physiological processes. The AtMRS2/MGT family, which contains nine Arabidopsis genes (and two pseudogenes),…”
Get full text

Rapid Calmodulin-dependent Interdomain Electron Transfer in Neuronal Nitric-oxide Synthase Measured by Pulse Radiolysis by Kobayashi, Kazuo, Tagawa, Seiichi, Daff, Simon, Sagami, Ikuko, Shimizu, Toru

“…Electron transfer within rat neuronal nitric-oxide synthase (nNOS) was investigated by pulse radiolysis. Radiolytically generated 1-methyl-3-carbamoyl…”
Get full text

Critical roles of Asp40 at the haem proximal side of haem‐regulated phosphodiesterase from Escherichia coli in redox potential, auto‐oxidation and catalytic control by Watanabe, Miki, Kurokawa, Hirofumi, Yoshimura‐Suzuki, Tokiko, Sagami, Ikuko, Shimizu, Toru

“…In haem‐regulated phosphodiesterase (PDE) from Escherichia coli (Ec DOS), haem is bound to the PAS domain, and the redox state of the haem iron regulates…”
Get full text

Identification of Caveolin-1-interacting Sites in Neuronal Nitric-oxide Synthase by Sato, Yuko, Sagami, Ikuko, Shimizu, Toru

“…Caveolin is known to down-regulate both neuronal (nNOS) and endothelial nitric-oxide synthase (eNOS). In the present study, direct interactions of recombinant…”
Get full text

Relationships between Heme Incorporation, Tetramer Formation, and Catalysis of a Heme-regulated Phosphodiesterase from Escherichia coli by Yoshimura, Tokiko, Sagami, Ikuko, Sasakura, Yukie, Shimizu, Toru

“…The heme-regulated phosphodiesterase (PDE) from Escherichia coli (Ec DOS) is a tetrameric protein composed of an N-terminal sensor domain (amino acids 1-201)…”
Get full text

Fluorescence Spectra of Trp53Phe and Trp110Ile Mutants of a Heme-regulated Phosphodiesterase from Escherichia coli by Hirata, Satoshi, Kurokawa, Hirofumi, Sagami, Ikuko, Shimizu, Toru

“…Fluorescence bands of a Trp110Ile mutant of the isolated heme domain of a heme-regulated phosphodiesterase (Ec DOS) from Escherichia coli and its complex with…”
Get full text