Search Results - "Safy, Mary"

AZD9567 versus prednisolone in patients with active rheumatoid arthritis: A phase IIa, randomized, double‐blind, efficacy, and safety study by Laar, Jacob M., Lei, Alejhandra, Safy‐Khan, Mary, Almquist, Joachim, Belfield, Graham, Edman, Karl, Öberg, Lisa, Angermann, Bastian R., Dillmann, Inken, Berntsson, Pia, Etal, Damla, Dainty, Ian, Astbury, Carol, Belvisi, Maria G., Nemes, Szilárd, Platt, Adam, Prothon, Susanne, Samuelsson, Sara, Svanberg, Petter, Keen, Christina, Jacobs, J. W. G., Kaan, Ellen, Tubergen, Astrid, Hermans, Kasper, Vonkeman, Harald, Moghadam, Marjan Ghiti, Gjertsson, Inger, Ekwall, Anna‐Karin, Kapetanovic, Meliha, Einarsson, Jon Thorkell, Axelsson, Lena T., Olsson, Richard, Myrbäck, Tove Hegelund, Taib, Ziad, Vikman, Kerstin

“…Oral corticosteroid use is limited by side effects, some caused by off‐target actions on the mineralocorticoid receptor that disrupt electrolyte balance…”
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Human Lymph Node Stromal Cells Have the Machinery to Regulate Peripheral Tolerance during Health and Rheumatoid Arthritis by Hähnlein, Janine S, Nadafi, Reza, Jong, Tineke A de, Semmelink, Johanna F, Remmerswaal, Ester B M, Safy, Mary, Lienden, Krijn P van, Maas, Mario, Gerlag, Danielle M, Tak, Paul P, Mebius, Reina E, Wähämaa, Heidi, Catrina, Anca I, G M van Baarsen, Lisa

“…In rheumatoid arthritis (RA) the cause for loss of tolerance and anti-citrullinated protein antibody (ACPA) production remains unidentified. Mouse studies…”
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Effects of B-cell directed therapy on the preclinical stage of rheumatoid arthritis: the PRAIRI study by Gerlag, Danielle M, Safy, Mary, Maijer, Karen I, Tang, Man Wai, Tas, Sander W, Starmans-Kool, Mirian J F, van Tubergen, Astrid, Janssen, Matthijs, de Hair, Maria, Hansson, Monika, de Vries, Niek, Zwinderman, Aeilko H, Tak, Paul P

“…We explored the effects of B-cell directed therapy in subjects at risk of developing autoantibodypositive rheumatoid arthritis (RA), who never experienced…”
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Effect of rituximab treatment on T and B cell subsets in lymph node biopsies of patients with rheumatoid arthritis by Ramwadhdoebe, Tamara H, van Baarsen, Lisa G M, Boumans, Maria J H, Bruijnen, Stefan T G, Safy, Mary, Berger, Ferco H, Semmelink, Johanna F, van der Laken, Conny J, Gerlag, Danielle M, Thurlings, Rogier M, Tak, Paul P

“…The exact underlying mechanism of rituximab treatment in patients with RA is poorly defined and knowledge about the effect of B cell depletion on immune cells…”
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089Co-Morbidities after Daily Concomitant Treatment with 10 Mg Prednisone or Placebo in the 2 Year Computer-Assisted Management in Early Rheumatoid Arthritis Trial II by de Hair, Maria J H, Safy, Mary, IJff, Nicole, Jacobs, Johannes W G, van Laar, Jacob M

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Current smoking negatively affects the response to methotrexate in RA in a dose-responsive way, independently of concomitant prednisone use by Safy-Khan, Mary, de Hair, Maria J H, Welsing, Paco M J, van Laar, Jacob M, Jacobs, Johannes W G

“…Current smoking reduces clinical response to several disease-modifying antirheumatic drugs (DMARDs). It is unknown if this is also the case for prednisone. We…”
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Current Smoking Negatively Affects the Response to Methotrexate in Rheumatoid Arthritis in a Dose-responsive Way, Independently of Concomitant Prednisone Use by Safy-Khan, Mary, de Hair, Maria J.H., Welsing, Paco M.J., van Laar, Jacob M., Jacobs, Johannes W.G.

“…Objective Current smoking reduces clinical response to several disease-modifying antirheumatic drugs. It is unknown if this is also the case for prednisone. We…”
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Effect on efficacy and safety trial outcomes of also enrolling patients on ongoing glucocorticoid therapy in rheumatoid arthritis clinical trials of tocilizumab or adalimumab or methotrexate monotherapy by Safy-Khan, Mary, Jacobs, Johannes W G, de Hair, Maria J H, Welsing, Paco M J, Edwardes, Michael D, Teitsma, Xavier M, Luder, Yves, Devenport, Jenny, van Laar, Jacob M, Pethoe-Schramm, Attila, Bijlsma, Johannes W J

“…In rheumatoid arthritis (RA) trials, inclusion of patients on background treatment with glucocorticoids (GCs) might impact efficacy and safety outcomes. To…”
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