Search Results - "Safwani, Wan Kamarul Zaman Wan"

Effect of hypoxia on human adipose-derived mesenchymal stem cells and its potential clinical applications by Choi, Jane Ru, Yong, Kar Wey, Wan Safwani, Wan Kamarul Zaman

“…Human adipose-derived mesenchymal stem cells (hASCs) are an ideal cell source for regenerative medicine due to their capabilities of multipotency and the…”
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Biosafety evaluation of culture-expanded human chondrocytes with growth factor cocktail: a preclinical study by Al-Masawa, Maimonah-Eissa, Wan Kamarul Zaman, Wan Safwani, Chua, Kien-Hui

“…The scarcity of chondrocytes is a major challenge for cartilage tissue engineering. Monolayer expansion is necessary to amplify the limited number of…”
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Impact of low oxygen tension on stemness, proliferation and differentiation potential of human adipose-derived stem cells by Choi, Jane Ru, Pingguan-Murphy, Belinda, Wan Abas, Wan Abu Bakar, Noor Azmi, Mat Adenan, Omar, Siti Zawiah, Chua, Kien Hui, Wan Safwani, Wan Kamarul Zaman

“…•Hypoxia maintains the stemness of adipose-derived stem cells (ASCs).•ASCs show an increased proliferation rate under low oxygen tension.•Oxygen level as low…”
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Polarized Light-Based Cancer Cell Detection Techniques: A Review by Tukimin, Siti Nurainie, Karman, Salmah Binti, Ahmad, Mohd Yazed, Wan Kamarul Zaman, Wan Safwani

“…Cancer is becoming raging phenomenon in clinical and pharmaceutical studies worldwide. It can be diagnosed by several step, including physical examination,…”
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Phenotypic and Functional Characterization of Long-Term Cryopreserved Human Adipose-derived Stem Cells by Yong, Kar Wey, Pingguan-Murphy, Belinda, Xu, Feng, Abas, Wan Abu Bakar Wan, Choi, Jane Ru, Omar, Siti Zawiah, Azmi, Mat Adenan Noor, Chua, Kien Hui, Safwani, Wan Kamarul Zaman Wan

“…Cryopreservation represents an effective technique to maintain the functional properties of human adipose-derived stem cells (ASCs) and allows pooling of cells…”
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MSCs vs. iPSCs: Potential in therapeutic applications by Thanaskody, Kalaiselvaan, Jusop, Amirah Syamimi, Tye, Gee Jun, Wan Kamarul Zaman, Wan Safwani, Dass, Sylvia Annabel, Nordin, Fazlina

“…Over the past 2 decades, mesenchymal stem cells (MSCs) have attracted a lot of interest as a unique therapeutic approach for a variety of diseases. MSCs are…”
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Biobanking of Human Mesenchymal Stem Cells: Future Strategy to Facilitate Clinical Applications by Yong, Kar Wey, Choi, Jane Ru, Wan Safwani, Wan Kamarul Zaman

“…Human mesenchymal stem cells (hMSCs), a type of adult stem cells that hold great potential in clinical applications (e.g., regenerative medicine and cell-based…”
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Mesenchymal Stem Cell-Derived Extracellular Vesicles: Hype or Hope for Skeletal Muscle Anti-Frailty by Mahindran, Elancheleyen, Wan Kamarul Zaman, Wan Safwani, Ahmad Amin Noordin, Khairul Bariah, Tan, Yuen-Fen, Nordin, Fazlina

“…Steadily rising population ageing is a global demographic trend due to the advancement of new treatments and technologies in the medical field. This trend also…”
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Immunomodulation and Regenerative Capacity of MSCs for Long-COVID by Loke, Xin Ya, Imran, Siti A. M., Tye, Gee Jun, Wan Kamarul Zaman, Wan Safwani, Nordin, Fazlina

“…The rapid mutation of the SARS-CoV-2 virus is now a major concern with no effective drugs and treatments. The severity of the disease is linked to the…”
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Modelling of Stem Cells Microenvironment Using Carbon-Based Scaffold for Tissue Engineering Application—A Review by Vitus, Vieralynda, Ibrahim, Fatimah, Wan Kamarul Zaman, Wan Safwani

“…A scaffold is a crucial biological substitute designed to aid the treatment of damaged tissue caused by trauma and disease. Various scaffolds are developed…”
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In situ normoxia enhances survival and proliferation rate of human adipose tissue-derived stromal cells without increasing the risk of tumourigenesis by Choi, Jane Ru, Pingguan-Murphy, Belinda, Wan Abas, Wan Abu Bakar, Yong, Kar Wey, Poon, Chi Tat, Noor Azmi, Mat Adenan, Omar, Siti Zawiah, Chua, Kien Hui, Xu, Feng, Wan Safwani, Wan Kamarul Zaman

“…Adipose tissue-derived stromal cells (ASCs) natively reside in a relatively low-oxygen tension (i.e., hypoxic) microenvironment in human body. Low oxygen…”
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Paracrine Effects of Adipose-Derived Stem Cells on Matrix Stiffness-Induced Cardiac Myofibroblast Differentiation via Angiotensin II Type 1 Receptor and Smad7 by Yong, Kar Wey, Li, Yuhui, Liu, Fusheng, Bin Gao, Lu, Tian Jian, Wan Abas, Wan Abu Bakar, Wan Safwani, Wan Kamarul Zaman, Pingguan-Murphy, Belinda, Ma, Yufei, Xu, Feng, Huang, Guoyou

“…Human mesenchymal stem cells (hMSCs) hold great promise in cardiac fibrosis therapy, due to their potential ability of inhibiting cardiac myofibroblast…”
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Biosafety and bioefficacy assessment of human mesenchymal stem cells: what do we know so far? by Yong, Kar Wey, Choi, Jane Ru, Dolbashid, Asdani Saifullah, Wan Safwani, Wan Kamarul Zaman

“…An outstanding amount of resources has been used in research on manipulation of human stem cells, especially mesenchymal stem cells (MSCs), for various…”
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Development of brain organoid technology derived from iPSC for the neurodegenerative disease modelling: a glance through by Jusop, Amirah Syamimi, Thanaskody, Kalaiselvaan, Tye, Gee Jun, Dass, Sylvia Annabel, Wan Kamarul Zaman, Wan Safwani, Nordin, Fazlina

“…Neurodegenerative diseases are adult-onset neurological conditions that are notoriously difficult to model for drug discovery and development because most…”
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Effects of simple knee sleeves on pain and knee adduction moment in early unilateral knee osteoarthritis by Mohd Sharif, Nahdatul Aishah, Usman, Juliana, Wan Safwani, Wan Kamarul Zaman, Siew Li, Goh, Abdul Karim, Samihah, Mohamed, Nur Anisah, Khan, Soobia Saad, Khan, Saad Jawaid

“…Knee sleeves are often prescribed to alleviate pain in people with early knee osteoarthritis. However, the biomechanics underlying their pain-relieving effect…”
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Stem Cells and Cancer Stem Cells: The Jekyll and Hyde Scenario and Their Implications in Stem Cell Therapy by Wan Kamarul Zaman, Wan Safwani, Nurul, Asma Abdullah, Nordin, Fazlina

“…“Jekyll and Hyde” refers to persons with an unpredictably dual personality, who are battling between good and evil within themselves In this regard, even cells…”
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Integrase deficient lentiviral vector: prospects for safe clinical applications by Yew, Chee-Hong Takahiro, Gurumoorthy, Narmatha, Nordin, Fazlina, Tye, Gee Jun, Wan Kamarul Zaman, Wan Safwani, Tan, Jun Jie, Ng, Min Hwei

“…HIV-1 derived lentiviral vector is an efficient transporter for delivering desired genetic materials into the targeted cells among many viral vectors. Genetic…”
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Suppression of the Viability and Proliferation of HepG2 Hepatocellular Carcinoma Cell Line by Konjac Glucomannan by Sawai, Sakunie, Mohktar, Mas Sahidayana, Safwani, Wan Kamarul Zaman Wan, Ramasamy, Thamil Selvee

“…Konjac Glucomannan (KGM) is a water-soluble dietary fibre extracted from Amorphophallus konjac K. Koch (Araceae). Konjac fibre has been clinically proven as an…”
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Non-Integrating Lentiviral Vectors in Clinical Applications: A Glance Through by Gurumoorthy, Narmatha, Nordin, Fazlina, Tye, Gee Jun, Wan Kamarul Zaman, Wan Safwani, Ng, Min Hwei

“…Lentiviral vectors (LVs) play an important role in gene therapy and have proven successful in clinical trials. LVs are capable of integrating specific genetic…”
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Autologous Human Mesenchymal Stem Cell-Based Therapy in Infertility: New Strategies and Future Perspectives by Mohamed Rasheed, Zahirrah Begam, Nordin, Fazlina, Wan Kamarul Zaman, Wan Safwani, Tan, Yuen-Fen, Abd Aziz, Nor Haslinda

“…Infertility could be associated with a few factors including problems with physical and mental health, hormonal imbalances, lifestyles, and genetic factors…”
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