Data on gut metagenomes of the patients with Helicobacter pylori infection before and after the antibiotic therapy

Antibiotic therapy can lead to the disruption of gut microbiota community with possible negative outcomes for human health. One of the diseases for which the treatment scheme commonly included antibiotic intake is Helicobacter pylori infection. The changes in taxonomic and functional composition of...

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Bibliographic Details
Published in:	Data in brief Vol. 11; no. C; pp. 68 - 71
Main Authors:	Glushchenko, Oksana E., Samoilov, Andrei E., Olekhnovich, Evgenii I., Kovarsky, Boris A., Tyakht, Alexander V., Pavlenko, Alexander V., Babenko, Vlad V., Larin, Andrei K., Kostryukova, Elena S., Malakhova, Maja V., Ilina, Elena N., Abdulkhakov, Rustem A., Safina, Dilyara I., Grigoryeva, Tatiana V., Abdulkhakov, Sayar R., Govorun, Vadim M.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Inc 01-04-2017 Elsevier
Subjects:	Antibiotic therapy Data Gut microbiota Helicobacter pylori Metagenome Gut microbiota Helicobacter pylori Metagenome Antibiotic therapy
Online Access:	Get full text
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Summary:	Antibiotic therapy can lead to the disruption of gut microbiota community with possible negative outcomes for human health. One of the diseases for which the treatment scheme commonly included antibiotic intake is Helicobacter pylori infection. The changes in taxonomic and functional composition of microbiota in patients can be assessed using “shotgun” metagenomic sequencing. Ten stool samples were collected from 4 patients with Helicobacter pylori infection before and directly after the H. pylori eradication course. Additionally, for two of the subjects, the samples were collected 1 month after the end of the treatment. The samples were subject to “shotgun” (whole-genome) metagenomic sequencing using Illumina HiSeq platform. The reads are deposited in the ENA (project ID: PRJEB18265).
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	2352-3409 2352-3409
DOI:	10.1016/j.dib.2017.01.007