Search Results - "Safhi, M. M."

Neuroprotective effect of naringenin is mediated through suppression of NF-κB signaling pathway in experimental stroke by Raza, S.S, Khan, M.M, Ahmad, A, Ashafaq, M, Islam, F, Wagner, A.P, Safhi, M.M

“…Highlights ► MCAO impairs motor balance and significantly increases oxidative loads and inflammation. ► Oxidative stress contributes to the NF-κB-associated…”
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1,8-Cineole (Eucalyptol) Mitigates Inflammation in Amyloid Beta Toxicated PC12 Cells: Relevance to Alzheimer’s Disease by Khan, Andleeb, Vaibhav, Kumar, Javed, Hayate, Tabassum, Rizwana, Ahmed, Md. Ejaz, Khan, Mohd. Moshahid, Khan, M. Badruzzaman, Shrivastava, Pallavi, Islam, Farah, Siddiqui, M. Saeed, Safhi, M. M., Islam, Fakhrul

“…Inflammatory process has a fundamental role in the pathogenesis of Alzheimer’s disease and insoluble amyloid beta deposits and neurofibrillary tangles provide…”
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Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type by Javed, H, Khan, M.M, Ahmad, A, Vaibhav, K, Ahmad, M.E, Khan, A, Ashafaq, M, Islam, F, Siddiqui, M.S, Safhi, M.M

“…Abstract The objective of the present study was to assess the neuroprotective role of rutin (vitamin P) and delineate the mechanism of action. Recent evidence…”
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Potency of nano-antibacterial formulation from Sargassum binderi against selected human pathogenic bacteria by Moni, Sivakumar Sivagurunathan, Alam, Mohammad Firoz, Safhi, M M., Jabeen, Aamena, Sanobar, Syeda, Siddiqui, Rahimullah, Moochikkal, Remesh

“…Seaweeds constitutes an abundant marine reserve that can be harnessed as source of new pharmaceutical agents. Sargassum binderi Sonder ex J. Agardh is a brown…”
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Effect of hesperidin on neurobehavioral, neuroinflammation, oxidative stress and lipid alteration in intracerebroventricular streptozotocin induced cognitive impairment in mice by Javed, Hayate, Vaibhav, Kumar, Ahmed, M. Ejaz, Khan, Andleeb, Tabassum, Rizwana, Islam, Farah, Safhi, Mohammed M, Islam, Fakhrul

“…Abstract Recent attention is given to the influence of dietary supplementation on health and mental well-being. Oxidative stress is associated with many…”
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Anti-apoptotic and Anti-inflammatory effect of Piperine on 6-OHDA induced Parkinson's Rat model by Shrivastava, Pallavi, Vaibhav, Kumar, Tabassum, Rizwana, Khan, Andleeb, Ishrat, Tauheed, Khan, Mohd. Moshahid, Ahmad, Ajmal, Islam, Farah, Safhi, Mohammed M, Islam, Fakhrul

“…In the present study, we examined the molecular mechanism by which Piperine (bioactive compound of Piper nigrum) inhibits neuronal cell apoptosis. We further…”
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Hesperidin ameliorates functional and histological outcome and reduces neuroinflammation in experimental stroke by Raza, Syed Shadab, Khan, Mohd. Moshahid, Ahmad, Ajmal, Ashafaq, Mohammad, Khuwaja, Gulrana, Tabassum, Rizwana, Javed, Hayate, Siddiqui, Mohammad Saeed, Safhi, Mohammed M, Islam, Fakhrul

“…Abstract Incidence of stroke is considered to be a major cause of death throughout the world. The middle cerebral artery occlusion (MCAO) for 2 h followed by…”
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Antibacterial effect of diode laser on different cariogenic bacteria: An In-vitro study by Vinothkumar, T S, Apathsakayan, R, M El-Shamy, F M, Homeida, H E, Hommedi, A I M, A Safhi, M Y, Alsalhi, H A M

“…The authors have used an in vitro model to appraise the antimicrobial efficacy of diode lasers with two different power outputs on Streptococcus mutans (SM),…”
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Rutin Protects Dopaminergic Neurons from Oxidative Stress in an Animal Model of Parkinson’s Disease by Moshahid Khan, Mohd, Raza, Syed Shadab, Javed, Hayate, Ahmad, Ajmal, Khan, Andleeb, Islam, Farah, Safhi, Mohammed M., Islam, Fakhrul

“…This study was undertaken to investigate the neuroprotective effects of rutin (vitamin P) on 6-hydroxydopamine (6-OHDA)-induced Parkinson’s disease (PD) in…”
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Prevalence and associated factors of pediatric hypertension in Jazan region, south of the Kingdom of Saudi Arabia. A pilot cross-sectional study by El-Setouhy, Maged, Safhi, Abdulrahman M, Dallak, Musab Y, Ayoub, Ahmed Y, Suwaid, Osama A H, Moafa, Ahmed K, Al-Ahmed, Alhassan M, Zaino, Mohammad, Al Sayed, Ahmed

“…Hypertension (HTN) is a primary global health concern. Moreover, according to the 2010 Global Burden of Disease, hypertension accounted for roughly a quarter…”
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Hepatoprotective Potential of Sargassum muticum against STZ-Induced Diabetic Liver Damage in Wistar Rats by Inhibiting Cytokines and the Apoptosis Pathway by Anwer, Tarique, Sivakumar, Sivagurunathan Moni, Alam, Mohammad Firoz, Safhi, Mohammed M.

“…Liver inflammation and necrosis are the foremost problems interlinked with diabetes mellitus (DM). The methanolic extract of Sargassum muticum (MESM) plays a…”
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Gefitinib loaded nanostructured lipid carriers: characterization, evaluation and anti-human colon cancer activity in vitro by Makeen, Hafiz A., Mohan, Syam, Al-Kasim, Mohamed Ahmed, Attafi, Ibraheem M., Ahmed, Rayan A., Syed, Nabeel Kashan, Sultan, Muhammad Hadi, Al-Bratty, Mohammed, Alhazmi, Hassan A., Safhi, Mohammed M., Ali, Raisuddin, Intakhab Alam, M.

“…NLC containing Gefitinib (NANOGEF) was prepared using stearic acid, sesame oil and surfactants (sodium lauryl sulfate and tween 80). NANOGEFs were evaluated…”
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Thymoquinone Ameliorates Doxorubicin-Induced Cardiotoxicity in Swiss Albino Mice by Modulating Oxidative Damage and Cellular Inflammation by Anwer, Tarique, Siddiqui, Rahimullah, Alshahrani, Saeed, Safhi, Mohammed M., Khan, Gyas, Alam, Mohammad Firoz, Sivakumar, Sivagurunathan Moni

“…Thymoquinone is the active constituent of Nigella sativa, having antioxidant and anti-inflammatory actions. In present study, we have analyzed the effects of…”
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Quercetin Protects Against Oxidative Stress Associated Damages in a Rat Model of Transient Focal Cerebral Ischemia and Reperfusion by Ahmad, Ajmal, Khan, Mohd. Moshahid, Hoda, Md. Nasrul, Raza, Syed Shadab, Khan, M. Badruzzaman, Javed, Hayate, Ishrat, Tauheed, Ashafaq, Mohammad, Ahmad, Md. Ejaz, Safhi, Mohammed M., Islam, Fakhrul

“…Experimental studies have demonstrated that oxidative stress and apoptosis play an important role in cerebral ischemic pathogenesis and may represent a target…”
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Neuroprotective effects of curcumin on 6-hydroxydopamine-induced Parkinsonism in rats: Behavioral, neurochemical and immunohistochemical studies by Khuwaja, Gulrana, Khan, Mohd. Moshahid, Ishrat, Tauheed, Ahmad, Ajmal, Raza, Syed Shadab, Ashafaq, Mohammad, Javed, Hayate, Khan, M. Badruzzaman, Khan, Andleeb, Vaibhav, Kumar, Safhi, Mohammed M, Islam, Fakhrul

“…Abstract Curcumin, the active principle of turmeric used in Indian curry is known for its antitumor, antioxidant, antiarthritic, anti-ischemic and…”
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Associations of Electronic Device Use and Physical Activity with Headaches in Saudi Medical Students by Alqassim, Ahmad Y, Alharbi, Abdullah A, Muaddi, Mohammed A, Makeen, Anwar M, Shuayri, Waleed H, Safhi, Abdelelah M, Alfifa, Abdulrahman Y, Samily, Idris H, Darbashi, Nawaf A, Otayn, Mohammed A, Moafa, Abdulaziz Y, Wafi, Ahmed M, Mahfouz, Mohamed Salih

“…Primary headaches are highly prevalent among medical students, negatively impacting their health and academic performance. Excessive electronic device use has…”
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Nephroprotective Effect of Zingerone against CCl4-Induced Renal Toxicity in Swiss Albino Mice: Molecular Mechanism by Safhi, Mohammed M.

“…The protective effects of Zingerone against CCl4 induced nephrotoxicity in Swiss albino mice via modulation of metabolizing enzyme, oxidative stress,…”
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Edaravone ameliorates oxidative stress associated cholinergic dysfunction and limits apoptotic response following focal cerebral ischemia in rat by Ahmad, Ajmal, Moshahid Khan, Mohd, Javed, Hayate, Raza, Syed Shadab, Ishrat, Tauheed, Badruzzaman Khan, M., Safhi, Mohammed M., Islam, Fakhrul

“…Stroke is a life-threatening disease with major cause of mortality and morbidity worldwide. The neuronal damage following cerebral ischemia is a serious risk…”
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Pharmacological melioration by Selenium on the toxicity of tellurium in neuroendocrine centre (Pituitary Gland) in male wistar rats: A mechanistic approach by Khuwaja, Gulrana, Al-Bratty, Mohammed, Alhazmi, Hassan A., Khan, Andleeb, Safhi, Mohammad M., Ashafaq, Mohammad, Islam, Farha, Islam, Fakhrul, Taha, Manal M.

“…The present research was designed to evaluate the toxicity of tellurium and its prevention by selenium on the pituitary gland in male Wistar rats. 30 rats were…”
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Catha Edulis Active Principle, Cathinone, Suppresses Motor Coordination, Accelerates Anxiety and Alters the Levels of Dopamine and its Metabolites in the Limbic Areas of Male Swiss Albino Mice by Safhi, Mohammed M., Alam, Mohammad Firoz, Khuwaja, Gulrana, Hussain, Sohail, Siddiqui, Mohammed Hakeem, Islam, Farah, Khardali, Ibrahim, Al-Sanosi, Rashad Mohammed, Alhazmi, Hassan A., Khan, Andleeb, Islam, Fakhrul

“…Cathinone, the active principle of khat (Catha edulis), stimulates, excites and produces euphoric feelings in khat users. Locomotor and rearing activities,…”
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