Search Results - "Safhi, Awaji Y"

Three-Dimensional (3D) Printing in Cancer Therapy and Diagnostics: Current Status and Future Perspectives by Safhi, Awaji Y

“…Three-dimensional (3D) printing is a technique where the products are printed layer-by-layer via a series of cross-sectional slices with the exact deposition…”
Get full text

CD44-Targeted Nanocarrier for Cancer Therapy by Kesharwani, Prashant, Chadar, Rahul, Sheikh, Afsana, Rizg, Waleed Y, Safhi, Awaji Y

“…Cluster of differentiation 44 (CD44) is a cell surface glycoprotein overexpressed in varieties of solid tumors including pancreatic, breast, ovary, brain, and…”
Get full text

Synthesis, Characterization, and Investigation of Novel Ionic Liquid-Based Tooth Bleaching Gels: A Step towards Safer and Cost-Effective Cosmetic Dentistry by Satti, Memuna Kausar, Nayyer, Maleeha, Alshamrani, Meshal, Kaleem, Muhammad, Salawi, Ahmad, Safhi, Awaji Y, Alsalhi, Abdullah, Sabei, Fahad Y, Khan, Abdul Samad, Muhammad, Nawshad

“…The objective of this study was to synthesize a novel choline hydroxide ionic liquid-based tooth bleaching gel. Ionic liquid-based gels were synthesized and…”
Get full text

Macrophages M2 polarization is involved in lapatinib-mediated chemopreventive effects in the lung cancer by Tariq, Muhammad, Hussain, Nadia, Rehman, Kanwal, Akash, Muhammad Sajid Hamid, Al Haddad, Amal H.I., Said, Amira S.A., Fatease, Adel Al, Alamri, Ali, Safhi, Awaji Y., Sabei, Fahad Y., Awadh, Ahmed Abdullah Al, Hussain, Musaddique

“…M2 polarized tumor-associated macrophages (TAMs) have a multifunctional role in cancer initiation, progression, metastasis, and contribute to chemotherapeutic…”
Get full text

Fabrication, In Vitro, and In Vivo Assessment of Eucalyptol-Loaded Nanoemulgel as a Novel Paradigm for Wound Healing by Rehman, Anis, Iqbal, Muhammad, Khan, Barkat A, Khan, Muhammad Khalid, Huwaimel, Bader, Alshehri, Sameer, Alamri, Ali H, Alzhrani, Rami M, Bukhary, Deena M, Safhi, Awaji Y, Hosny, Khaled M

“…Wounds are the most common causes of mortality all over the world. Topical drug delivery systems are more efficient in treating wounds as compared to oral…”
Get full text

Polycaprolactone based pharmaceutical nanoemulsion loaded with acriflavine: optimization and in vivo burn wound healing activity by Nawaz, Touseef, Iqbal, Muhammad, Khan, Barkat Ali, Ahmed, Naveed, Nawaz, Asif, Rasul, Akhtar, Rizg, Waleed Y., Jali, Abdulmajeed M., Ahmed, Rayan A., Safhi, Awaji Y.

“…Cutaneous burn wounds are a common and troublesome critical issue of public health. Over the last decade, many researchers have investigated the development of…”
Get full text

Plant-Derived Bioactive Compounds in the Management of Neurodegenerative Disorders: Challenges, Future Directions and Molecular Mechanisms Involved in Neuroprotection by Shoaib, Shoaib, Ansari, Mohammad Azam, Fatease, Adel Al, Safhi, Awaji Y, Hani, Umme, Jahan, Roshan, Alomary, Mohammad N, Ansari, Mohd Nazam, Ahmed, Nabeel, Wahab, Shadma, Ahmad, Wasim, Yusuf, Nabiha, Islam, Najmul

“…Neurodegenerative disorders encompass a wide range of pathological conditions caused by progressive damage to the neuronal cells and nervous-system…”
Get full text

Enhancement of antifungal activity and transdermal delivery of 5-flucytosine via tailored spanlastic nanovesicles: statistical optimization, in-vitro characterization, and in-vivo biodistribution study by Safhi, Awaji Y, Naveen, Nimbagal Raghavendra, Rolla, Krishna Jayanth, Bhavani, Penmetsa Durga, Kurakula, Mallesh, Hosny, Khaled M, Abualsunun, Walaa A, Alissa, Mohammed, Alsalhi, Abdullah, Alahmadi, Amerh Aiad, Zoghebi, Khalid, Halwaani, Abdulrahman Sindam, Ibrahim K, Rasha

“…This current study aimed to load 5-flucytosine (5-FCY) into spanlastic nanovesicles (SPLNs) to make the drug more efficient as an antifungal and also to load…”
Get full text

Statistically Optimized Polymeric Buccal Films of Eletriptan Hydrobromide and Itopride Hydrochloride: An In Vivo Pharmacokinetic Study by Safhi, Awaji Y, Siddique, Waqar, Zaman, Muhammad, Sarfraz, Rai Muhammad, Shafeeq Ur Rahman, Muhammad, Mahmood, Asif, Salawi, Ahmad, Sabei, Fahad Y, Alsalhi, Abdullah, Zoghebi, Khalid

“…A migraine is a condition of severe headaches, causing a disturbance in the daily life of the patient. The current studies were designed to develop…”
Get full text

Tailoring and optimization of a honey-based nanoemulgel loaded with an itraconazole-thyme oil nanoemulsion for oral candidiasis by Sindi, Amal M., Rizg, Waleed Y., Khan, Muhammad Khalid, Alkhalidi, Hala M., Alharbi, Waleed S., Sabei, Fahad Y., Alfayez, Eman, Alkharobi, Hanaa, Korayem, Mohammed, Majrashi, Mohammed, Alharbi, Majed, Alissa, Mohammed, Safhi, Awaji Y., Jali, Abdulmajeed M., Hosny, Khaled M.

“…The use of essential oil-based nanoemulsions (NEs) has been the subject of extensive research on a variety of conditions affecting the oral cavity. NEs are…”
Get full text

Preparation and optimization of aloe ferox gel loaded with Finasteride-Oregano oil nanocubosomes for treatment of alopecia by Hosny, Khaled M., Rizg, Waleed Y., Alfayez, Eman, Elgebaly, Samar S., Alamoudi, Abdulmohsin J., Felimban, Raed I., Tayeb, Hossam H., Mushtaq, Rayan Y., Safhi, Awaji Y., Alharbi, Majed, Almehmady, Alshaimaa M.

“…Alopecia areata is a skin disorder characterized by scarless, localized hair loss that is usually managed by topical treatments that might further worsen the…”
Get full text

Production, Characterization, and In Vitro and In Vivo Studies of Nanoemulsions Containing St. John's Wort Plant Constituents and Their Potential for the Treatment of Depression by Salawi, Ahmad, Almoshari, Yosif, Sultan, Muhammad H, Madkhali, Osama A, Bakkari, Mohammed Ali, Alshamrani, Meshal, Safhi, Awaji Y, Sabei, Fahad Y, Al Hagbani, Turki, Ali, Md Sajid, Alam, Md Sarfaraz

“…The current project was designed to prepare an oil-in-water (oil/water) hypericin nanoemulsion using eucalyptus oil for the preparation of an oil phase with…”
Get full text

Development of Novel S-Protective Thiolated-Based Mucoadhesive Tablets for Repaglinide: Pharmacokinetic Study by Alhakamy, Nabil A, Naveen, Nimbagal Raghavendra, Gorityala, Shashank, Kurakula, Mallesh, Hosny, Khaled M, Safhi, Awaji Y, Bukhary, Deena M, Bukhary, Haitham A, Sabei, Fahad Y, Mushtaq, Rayan Y, Murshid, Samar S

“…Mucoadhesive polymers have an essential role in drug localization and target-specific actions in oral delivery systems. The current work aims to develop and…”
Get full text

Formulation development of lipid polymer hybrid nanoparticles of doxorubicin and its in-vitro, in-vivo and computational evaluation by Shafique, Muhammad, Ur Rehman, Maqsood, Kamal, Zul, Alzhrani, Rami M, Alshehri, Sameer, Alamri, Ali H, Bakkari, Mohammed Ali, Sabei, Fahad Y, Safhi, Awaji Y, Mohammed, Ahmed M, Hamd, Mohamed A El, Almawash, Saud

“…The purpose of this study was to assess the parameters of doxorubicin (DOX) loaded lipid polymer hybrid nanoparticles (LPHNs) formulation development, and then…”
Get full text

Biodegradable Polymers-Based Smart Nanocrystals for Loxoprofen Delivery with Enhanced Solubility: Design, Fabrication and Physical Characterizations by Khan, Barkat Ali, Khalid, Hina, Khan, Muhammad Khalid, Hosny, Khaled M, Khan, Shahzeb, Rizg, Waleed Y, Safhi, Awaji Y, Halwani, Abdulrahman A, Almehmady, Alshaimaa M, Menaa, Farid

“…Nanocrystals are carrier-free, submicron-sized, colloidal drug delivery systems with particle sizes in the mean nanometer range. Nanocrystals have high…”
Get full text

Development and optimization of a tamsulosin nanostructured lipid carrier loaded with saw palmetto oil and pumpkin seed oil for treatment of benign prostatic hyperplasia by Bakhaidar, Rana B., Hosny, Khaled M., Mahier, Imman M., Rizq, Waleed Y., Safhi, Awaji Y., Bukhary, Deena M., Sultan, Muhammad H., Bukhary, Haitham A., Madkhali, Osama A., Sabei, Fahad Y.

“…Benign prostatic hyperplasia (BPH) is a nonmalignant growth of the prostate tissue and causes urinary tract symptoms. To provide effective treatment,…”
Get full text

Development and evaluation of pH sensitive semi-interpenetrating networks: assessing the impact of itaconic acid and aloe vera on network swelling and cetirizine release by Ajaz, Nyla, Bukhsh, Munnaza, Kamal, Yousaf, Rehman, Fauzia, Irfan, Muhammad, Khalid, Syed Haroon, Asghar, Sajid, Rizg, Waleed Y, Bukhary, Sahar M, Hosny, Khaled M, Alissa, Mohammed, Safhi, Awaji Y, Sabei, Fahad Y, Khan, Ikram Ullah

“…Hydrogels are crosslinked three-dimensional networks, and their properties can be easily tuned to target the various segments of the gastrointestinal tract…”
Get full text

Rapid oral transmucosal delivery of zaleplon-lavender oil utilizing self-nanoemulsifying lyophilized tablets technology: development, optimization and pharmacokinetic evaluation by Ali, Sarah A., Alhakamy, Nabil A., Hosny, Khaled M., Alfayez, Eman, Bukhary, Deena M., Safhi, Awaji Y., Badr, Moutaz Y., Mushtaq, Rayan Y., Alharbi, Majed, Huwaimel, Bader, Alissa, Mohammed, Alshehri, Sameer, Alamri, Ali H., Alqahtani, Taha

“…Based on the administration convenience, transmucosal buccal drug delivery allows special strength points over peroral routes for systemic delivery. It could…”
Get full text

In Vitro and In Vivo Evaluation of Composite Oral Fast Disintegrating Film: An Innovative Strategy for the Codelivery of Ranitidine HCl and Flurbiprofen by Rashid, Aisha, Khalid, Syed Haroon, Irfan, Muhammad, Asghar, Sajid, Rizg, Waleed Y, Sabei, Fahad Y, Alfayez, Eman, Alkharobi, Hanaa, Safhi, Awaji Y, Hosny, Khaled M, Arshad, Muhammad Sohail, Khan, Ikram Ullah

“…Here, we evaluate the feasibility of co-loading plain ranitidine hydrochloride (RHCl) and microencapsulated flurbiprofen (FBP) in a Lycoat RS780-based oral…”
Get full text

QbD Supported Optimization of the Alginate-Chitosan Nanoparticles of Simvastatin in Enhancing the Anti-Proliferative Activity against Tongue Carcinoma by Rizg, Waleed Y, Naveen, N Raghavendra, Kurakula, Mallesh, Bukhary, Haitham A, Safhi, Awaji Y, Alfayez, Eman, Sindi, Amal M, Ali, Sarah, Murshid, Samar S, Hosny, Khaled M

“…The goal of the current study is to develop a chitosan alginate nanoparticle system encapsulating the model drug, simvastatin (SIM-CA-NP) using a novel…”
Get full text