Search Results - "Safavi, Ashkan"

Immunoprotective effect of an in silico designed multiepitope cancer vaccine with BORIS cancer-testis antigen target in a murine mammary carcinoma model by Mahdevar, Elham, Kefayat, Amirhosein, Safavi, Ashkan, Behnia, Amirhossein, Hejazi, Seyed Hossein, Javid, Amaneh, Ghahremani, Fatemeh

“…In our previous study, immunoinformatic tools were used to design a novel multiepitope cancer vaccine based on the most immunodominant regions of BORIS…”
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Efficacy of co-immunization with the DNA and peptide vaccines containing SYCP1 and ACRBP epitopes in a murine triple-negative breast cancer model by Safavi, Ashkan, Kefayat, Amirhosein, Mahdevar, Elham, Ghahremani, Fatemeh, Nezafat, Navid, Modarressi, Mohammad Hossein

“…Multiepitope cancer vaccines have gained lots of attention for prophylactic and therapeutic purposes in cancer patients. In our previous study, multiepitope…”
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Identifying the most effective hydatid cyst fluid fraction for anticancer vaccination of 4T1 breast tumor-bearing mice by Daneshpour, Shima, Rostamirad, Shahla, Kefayat, Amirhosein, Mofid, MohammadReza, Safavi, Ashkan, Darani, Hossein

“…Background: The hydatid cyst fluid antigens have high homology with cancer cell antigens and also exhibit considerable immunogenicity. Therefore, their…”
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Exploring the out of sight antigens of SARS-CoV-2 to design a candidate multi-epitope vaccine by utilizing immunoinformatics approaches by Safavi, Ashkan, Kefayat, Amirhosein, Mahdevar, Elham, Abiri, Ardavan, Ghahremani, Fatemeh

“…•The vaccine is composed of immunodominant regions of SARS-CoV-2 non-structural proteins.•Also, the functional region of the spike protein is incorporated in…”
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C-phycocyanin: a natural product with radiosensitizing property for enhancement of colon cancer radiation therapy efficacy through inhibition of COX-2 expression by Kefayat, Amirhosein, Ghahremani, Fatemeh, Safavi, Ashkan, Hajiaghababa, Alireza, Moshtaghian, Jamal

“…Different chemical and nanomaterial agents have been introduced for radiosensitizing purposes. However, many researchers believe these agents are far away from…”
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In silico analysis of transmembrane protein 31 (TMEM31) antigen to design novel multiepitope peptide and DNA cancer vaccines against melanoma by Safavi, Ashkan, Kefayat, Amirhosein, Abiri, Ardavan, Mahdevar, Elham, Behnia, Amir Hossein, Ghahremani, Fatemeh

“…•The peptide and DNA cancer vaccines consisted of immunodominant fragments of TMEM31 antigen were designed in silico.•The immunodominant fragments were linked…”
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Production, purification, and in vivo evaluation of a novel multiepitope peptide vaccine consisted of immunodominant epitopes of SYCP1 and ACRBP antigens as a prophylactic melanoma vaccine by Safavi, Ashkan, Kefayat, Amirhosein, Sotoodehnejadnematalahi, Fattah, Salehi, Mansoor, Modarressi, Mohammad Hossein

“…Melanoma cells are significantly resistance to the current treatments. Therefore, the best option for high-risk populations is prevention. Recently, many…”
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Exploring the cancer-testis antigen BORIS to design a novel multi-epitope vaccine against breast cancer based on immunoinformatics approaches by Mahdevar, Elham, Safavi, Ashkan, Abiri, Ardavan, Kefayat, Amirhosein, Hejazi, Seyed Hossein, Miresmaeili, Seyed Mohsen, Iranpur Mobarakeh, Vahid

“…Recently, cancer immunotherapy has gained lots of attention to replace the current chemoradiation approaches and multi-epitope cancer vaccines are manifesting…”
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Spirulina extract enriched for Braun‐type lipoprotein (Immulina®) for inhibition of 4T1 breast tumors' growth and metastasis by Kefayat, Amirhosein, Ghahremani, Fatemeh, Safavi, Ashkan, Hajiaghababa, Alireza, Moshtaghian, Jamal

“…Spirulina platensis extracts have exhibited considerable anti‐cancer effects. To investigate the efficacy of the Spirulina extract enriched for Braun‐type…”
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In Silico Analysis of Synaptonemal Complex Protein 1 (SYCP1) and Acrosin Binding Protein (ACRBP) Antigens to Design Novel Multiepitope Peptide Cancer Vaccine Against Breast Cancer by Safavi, Ashkan, Kefayat, Amirhosein, Sotoodehnejadnematalahi, Fattah, Salehi, Mansoor, Modarressi, Mohammad Hossein

“…Multiepitope cancer vaccines are manifesting as the future of breast cancer immunotherapy. In the present study, high immunogenic fragments of synaptonemal…”
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Immunization using male germ cells and gametes as rich sources of cancer/testis antigens for inhibition of 4T1 breast tumors' growth and metastasis in BALB/c mice by Safavi, Ashkan, Kefayat, Amirhosein, Ghahremani, Fatemeh, Mahdevar, Elham, Moshtaghian, Jamal

“…Recently cancer/testis antigens (CTA) have gained lots of attention as targets of immune therapy. However, the therapeutic efficacy of the CTAs single-antigen…”
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