Search Results - "Safari, Elahe"
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Breast cancer: Biology, biomarkers, and treatments
Published in International immunopharmacology (01-07-2020)“…•BCSCs are the most critical cells leading to chemo and radio-resistance in tumor therapy.•Signaling pathways/metabolic components in BCSC could be targeted as…”
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Aquaporins in colorectal cancer: exploring their role in tumorigenesis, metastasis, and drug response
Published in Human cell : official journal of Human Cell Research Society (01-07-2024)“…Aquaporins (AQPs) are small, integral proteins facilitating water transport across plasma cell membranes in response to osmotic gradients. This family has 13…”
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Catalase-gold nanoaggregates manipulate the tumor microenvironment and enhance the effect of low-dose radiation therapy by reducing hypoxia
Published in Biomedicine & pharmacotherapy (01-11-2023)“…Radiotherapy as a standard method for cancer treatment faces tumor recurrence and antitumoral unresponsiveness. Suppressive tumor microenvironment (TME) and…”
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A review of the genus Caesalpinia L.: emphasis on the cassane and norcassane compounds and cytotoxicity effects
Published in Journal of medicinal plants (Online) (01-11-2020)“…Background: Many herbal remedies have been used in medical systems for the cure of diseases. One of these important applications is usage of them as cytotoxic…”
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Unraveling the potential of CD8, CD68, and VISTA as diagnostic and prognostic markers in patients with pancreatic ductal adenocarcinoma
Published in Frontiers in immunology (2024)“…Pancreatic cancer is a truculent disease with limited treatment options and a grim prognosis. Immunotherapy has shown promise in treating various types of…”
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Clinical Value of Serum S100A8/A9 and CA15-3 in the Diagnosis of Breast Cancer
Published in Iranian journal of pathology (2019)“…S100A8/A9 is a heterodimer calcium-binding protein which is involved in tumor cell proliferation, adhesion and invasion, and is proposed as a biomarker for…”
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Evaluation of tumor-educated platelet long non-coding RNAs (lncRNAs) as potential diagnostic biomarkers for colorectal cancer
Published in Journal of cancer research and therapeutics (01-07-2024)“…Cancer-derived circulating components are increasingly considered as candidate sources for non-invasive diagnostic biomarkers. This study aimed to investigate…”
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Immunomodulatory effects of astragalus polysaccharide on human peripheral blood mononuclear cells co-cultured with cervical cancer cell line
Published in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan (01-10-2021)“…To investigate immunomodulatory effects of Astragalus polysaccharides (APS) on the co-culture of peripheral blood mononuclear cells (PBMCs) with HeLa cervical…”
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Breast metastasis from gastric carcinoma: A case report
Published in Caspian journal of internal medicine (01-01-2022)“…There are rare cases of breast metastasis from gastric carcinoma origin. In this regard, we presented a case of signet ring cell stomach cancer with metastasis…”
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Placental Extract and Exosomes Derived from Pregnant Mice Attenuate the Development of Experimental Autoimmune Encephalomyelitis
Published in Iranian journal of allergy, asthma, and immunology (01-12-2022)“…Placental extract (PE) and exosomes from pregnant mice appear to have immunomodulatory and neuroprotective effects. In this study, we assessed the potential…”
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The immunomodulatory role of exosomal microRNA networks in the crosstalk between tumor-associated myeloid-derived suppressor cells and tumor cells
Published in International immunopharmacology (01-07-2023)“…•MDSC-derived exosomal miRNAs and those derived from tumor cells could.•Modulate the interaction between tumor cells and MDSCs in the TME.•Tumor-associated…”
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12
Immunomodulatory effects of shark cartilage: Stimulatory or anti-inflammatory
Published in Process biochemistry (1991) (01-05-2020)“…•Shark cartilage is a natural supplement for different diseases.•Shark cartilage have Anti-tumor and anti-angiogenesis function.•Shark cartilage have…”
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Breast cancer immunotherapy: Current and novel approaches
Published in International immunopharmacology (01-09-2021)“…•Combination of conventional therapy and immunotherapy approaches such as cancer vaccine could improve the overall survival rates of patients.•Simultaneous…”
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Myeloid‐derived suppressor cells and tumor: Current knowledge and future perspectives
Published in Journal of cellular physiology (01-07-2019)“…The immunosuppressive features of tumor lesions participate not only as one of the major players inducing cancer progression but also a big challenge for…”
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Immune and metabolic checkpoints blockade: Dual wielding against tumors
Published in International immunopharmacology (01-05-2021)“…•Immunometabolism plays critical roles in the immune exhaustion in cancer.•Exhausted T cells express immune checkpoints (ICs) and showed altered…”
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The immunomodulatory effects of low molecular weight garlic protein in crosstalk between peripheral blood mononuclear cells and colon cancer cells
Published in Process biochemistry (1991) (01-09-2021)“…[Display omitted] •Low Molecular Weight Garlic Proteins (LMWGP) have immunomodulatory effect against colon cancer cell in co-culture model.•LMWGP increase the…”
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Bioassay-guided Isolation of Flavonoids from Caesalpinia bonduc (L.) Roxb. and Evaluation of Their Cytotoxicity
Published in Iranian journal of pharmaceutical research : IJPR (2021)“…Cancer is one of the most important causes of death all around the world. Screening plants and their secondary metabolites as cytotoxic agents is one of the…”
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Astragalus Polysaccharide Mediates Immunomodulatory Effects on Crosstalk between Human Peripheral Blood Mononuclear Cells and Ovarian Cancer Cell Line
Published in Iranian journal of allergy, asthma, and immunology (01-04-2023)“…Astragalus polysaccharide (APS) is a functional component of Astragalus membranaceus with antitumor and immunomodulatory properties. This study evaluated the…”
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Candida albicans Beta-Glucan Induce Anti- Cancer Activity of Mesenchymal Stem Cells against Lung Cancer Cell Line: An In-Vitro Experimental Study
Published in Asian Pacific journal of cancer prevention : APJCP (01-03-2020)“…β-glucan, glucopyranosyl polymers of fungi cell wall, represent an immune stimulating effects with potential anti-cancer activity. Mesenchymal stem cells (MSC)…”
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High-expression of V-domain Imuunoglobulin Suppressor of T-cell Activation (VISTA) Is Correlated with Advanced Pathological Features in Patients with Pancreatic Ductal Adenocarcinoma
Published in Iranian journal of allergy, asthma, and immunology (27-05-2024)“…V-domain Imuunoglobulin suppressor of T-cell activation (VISTA) seems a promising immune checkpoint target in cancer treatment; however, its prognostic…”
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