Search Results - "Safaa I. Elewa"
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Experimental and computational studies of novel cyclic ammonium based ionic liquids as corrosion inhibitors for carbon steel in acid medium
Published in Scientific reports (20-05-2024)“…The challenge of corrosion posed as a result of acidic sittings is considered as a major industrial concern, wherein ionic liquids serve as crucial in…”
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Synthesis of Some New Pyrazoline-Based Thiazole Derivatives and Evaluation of Their Antimicrobial, Antifungal, and Anticancer Activities
Published in Russian journal of bioorganic chemistry (01-05-2020)“…3-(2-Thienyl)-5-aryl-1-thiocarbamoyl-2-pyrazolines were reacted with chloroacetone derivatives and hydrazonyl chloride derivatives in ethanol to afford the…”
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A new series of thiazolyl pyrazoline derivatives linked to benzo[1,3]dioxole moiety: Synthesis and evaluation of antimicrobial and anti-proliferative activities
Published in Synthetic communications (01-02-2020)“…2-(5-(Benzo[d][1,3]dioxol-5-yl)-3-(naphthalen-1-yl)-4,5-dihydro-1H-pyrazol-1-yl)-4-(4-substituted phenyl)thiazole (7) and thiazole derivatives (9) were…”
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Synthesis, characterization, antimicrobial activities, anticancer of some new pyridines from 2, 3-dihydro-2-oxo-4-phenyl-6-(thien-2-yl) pyridine-3-carbonitrile
Published in Synthetic communications (02-01-2021)“…2,3-Dihydro-2-oxo-4-phenyl-6-(thien-2-yl)pyridine-3-carbonitrile (4) was synthesized via reaction of four compounds (benzaldehyde, 2-acetylthiophene, ethyl…”
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Synthesis, and Cytotoxic Activity of Novel Pyrazoline-Thiazolidinone Derivatives with Molecular Docking Studies
Published in Polycyclic aromatic compounds (09-08-2023)“…1-(4-substitutesd)-2-(5-phenyl-3-(1H-pyrrol-2-yl)-4,5-dihydropyrazol-1-yl)thiazol-5-yl)-2-aryldiazene 9a-f were prepared through reactions of…”
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Synthesis, Docking and Anticancer Evaluation of New Pyridine-3-Carbonitrile Derivatives
Published in Polycyclic aromatic compounds (03-07-2022)“…N'-(2-((4-(Benzo[d][1, 3]dioxol-5-yl)-3-cyano-6-(naphthalen-2-yl)-pyridin-2-yl)oxy)- acetyl)benzohydrazide (6) and hydrazide derivatives (7-10) were…”
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Design, synthesis, and biological evaluation of furan-bearing pyrazolo[3,4-b]pyridines as novel inhibitors of CDK2 and P53-MDM2 protein-protein interaction
Published in Drug development research (01-09-2023)“…The novel series of furan-bearing pyrazolo[3,4-b]pyridines were designed as cyclin-dependent kinase 2 (CDK2) inhibitors and as p53-murine double minute…”
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Synthesis of Some Novel Indoline-2,3-Dione Derivatives and the Influence of Gamma Irradiation on Their Biological Activities
Published in Polycyclic aromatic compounds (26-11-2022)“…2-(2-oxoindolin-3-ylidene)-N-phenylhydrazinecarbothioamide (4) was synthesized by reaction of 3-hydrazonoindolin-2-one (3) with phenyl isothiocyanate in DMF in…”
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9
Synthesis and characterization of some tetrazoles and their prospective for aerobic micro-fouling mitigation
Published in Arabian journal of chemistry (01-12-2020)“…Two series of tetrazole derivatives of the type N-(1H-tetrazol-5-yl)-1-(aryl)methanimine (101–106) and 1-(4-alkoxyphenyl)-N-(1H-tetrazol-5-yl)methanimine…”
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10
Synthesis and Characterization of New Light Emitter Symmetrical Phenoxazinium Salt and Its Potential Application as Sensor for Assessment of Hg2
Published in Journal of fluorescence (01-05-2014)“…The sensitization of the excited triplet state of a novel symmetrical Bis(dialkylamino)phenoxazinium salt was developed in the presence of Hg 2+ . This effect…”
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11
Design, Synthesis of Novel Pyrido[2,3-d] pyrimidine Derivatives as SARS-CoV-2 Mpro Inhibitors for COVID-19 Therapy
Published in Polycyclic aromatic compounds (24-05-2024)Get full text
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Structural simplification of Osimertinib to elaborate new indolyle-pyrimidine-5-carbonitrile derivatives with Anti-proliferative and Anti-SARS-CoV-2 activities assisted by molecular dynamic simulation
Published in Tetrahedron (07-11-2024)“…Based on the simplicity and modification of the medication osimertinib, two new series of indolyle-pyrimidine-5-carbonitrile scaffolds were created and…”
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13
Anti-corrosion properties of new imidazolium-based ionic liquids as a function of cation structure
Published in Journal of molecular liquids (15-01-2022)“…•New five imidazolium-based ionic liquids were developed for anticorrosion application.•Ionic liquids structures were confirm by elemental, FT-IR, 13C, 1H NMR…”
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Design, synthesis, and biological evaluation of furan‐bearing pyrazolopyridines as novel inhibitors of CDK2 and P53–MDM2 protein–protein interaction
Published in Drug development research (01-09-2023)“…The novel series of furan‐bearing pyrazolo[3,4‐b]pyridines were designed as cyclin‐dependent kinase 2 (CDK2) inhibitors and as p53–murine double minute 2…”
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15
Synthesis and Characterization of New Light Emitter Symmetrical Phenoxazinium Salt and Its Potential Application as Sensor for Assessment of Hg super(2+)
Published in Journal of fluorescence (01-05-2014)“…The sensitization of the excited triplet state of a novel symmetrical Bis(dialkylamino)phenoxazinium salt was developed in the presence of Hg super(2+). This…”
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