Search Results - "Saez, Trinidad M."
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1
Prenatal exposure to the CB1 and CB2 cannabinoid receptor agonist WIN 55,212‐2 alters migration of early‐born glutamatergic neurons and GABAergic interneurons in the rat cerebral cortex
Published in Journal of neurochemistry (01-05-2014)“…The endocannabinoid system, composed of cannabinoid receptors, endocannabinoids, and synthesis and degradation enzymes, is present since early stages of brain…”
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2
αSynuclein control of mitochondrial homeostasis in human-derived neurons is disrupted by mutations associated with Parkinson’s disease
Published in Scientific reports (11-07-2017)“…The etiology of Parkinson’s disease (PD) converges on a common pathogenic pathway of mitochondrial defects in which α-Synuclein (αSyn) is thought to play a…”
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3
Neuronal KIF5b deletion induces striatum‐dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors
Published in Journal of neurochemistry (01-05-2019)“…The process of locomotion is controlled by fine‐tuned dopaminergic neurons in the Substantia Nigra pars‐compacta (SNpc) that projects their axons to the dorsal…”
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4
DYRK1A Regulates the Bidirectional Axonal Transport of APP in Human-Derived Neurons
Published in The Journal of neuroscience (17-08-2022)“…triplication in Down's syndrome and its overexpression in Alzheimer's disease suggest a role for increased DYRK1A activity in the abnormal metabolism of APP…”
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5
Kinesin-1-mediated axonal transport of CB1 receptors is required for cannabinoid-dependent axonal growth and guidance
Published in Development (Cambridge) (20-04-2020)“…Endocannabinoids (eCB) modulate growth cone dynamics and axonal pathfinding through the stimulation of cannabinoid type-1 receptors (CB1R), the function of…”
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6
Proteasome stress leads to APP axonal transport defects by promoting its amyloidogenic processing in lysosomes
Published in Journal of cell science (01-06-2018)“…Alzheimer disease (AD) pathology includes the accumulation of poly-ubiquitylated (also known as poly-ubiquitinated) proteins and failures in…”
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7
Neuronal KIF 5b deletion induces striatum ‐dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors
Published in Journal of neurochemistry (01-05-2019)Get full text
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8
Prenatal exposure to the CB 1 and CB 2 cannabinoid receptor agonist WIN 55,212‐2 alters migration of early‐born glutamatergic neurons and GABA ergic interneurons in the rat cerebral cortex
Published in Journal of neurochemistry (01-05-2014)“…The endocannabinoid system, composed of cannabinoid receptors, endocannabinoids, and synthesis and degradation enzymes, is present since early stages of brain…”
Get full text
Journal Article -
9
Kinesin-1-mediated axonal transport of CB1 receptors is required for cannabinoid-dependent axonal growth and guidance
Published in Development (Cambridge) (01-01-2020)“…Endocannabinoids modulate growth cone dynamics and axonal pathfinding through the stimulation of cannabinoid type-1 receptors (CB1R) which function depends on…”
Get full text
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