Risk Factors for Intraoperative Hypotension During Decompressive Craniectomy in traumatic Brain Injury Patients

Risk Factors for Intraoperative Hypotension During Decompressive Craniectomy in traumatic Brain Injury Patients

Decompressive craniectomy (DC) is an important therapy for treating intracranial pressure elevation following traumatic brain injury (TBI). During this procedure, about one-third of patients become complicated with intraoperative hypotension (IH), which is associated with abruptly decreasing sympath...

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Bibliographic Details
Published in:World neurosurgery Vol. 162; pp. e652 - e658
Main Authors: Saengrung, Suchada, Kaewborisutsakul, Anukoon, Tunthanathip, Thara, Phuenpathom, Nakornchai, Taweesomboonyat, Chin
Format: Journal Article
Language:English
Published: United States Elsevier Inc 01-06-2022
Subjects:
Decompressive craniectomy
Intraoperative hypotension
Risk factors
Traumatic brain injury
SBP
CPP
Traumatic brain injury
AIS
Intraoperative hypotension
Risk factors
Decompressive craniectomy
GCS
ICP
TBI
MAP
bpm
DC
GCS-M
IH
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Summary:Decompressive craniectomy (DC) is an important therapy for treating intracranial pressure elevation following traumatic brain injury (TBI). During this procedure, about one-third of patients become complicated with intraoperative hypotension (IH), which is associated with abruptly decreasing sympathetic activity resulting from brain decompression. This study aimed to identify factors associated with IH during DC procedures and the mortality rate in these patients. The records of adult TBI patients aged 18 years and older who underwent DC at Songklanagarind Hospital between January 2014 and January 2021 were retrospectively reviewed. Using logistic regression analysis, various factors were analyzed for their associations with IH during the DC procedures. This study included 83 patients. The incidence of IH was 54%. Multivariate analysis showed that Glasgow Coma Scale motor response (GCS-M) 1–3 (vs. 4–6), higher preoperative heart rate (PHR), and larger amount of intraoperative blood loss were significantly associated with IH (P = 0.013, P < 0.001, and P < 0.001, respectively). Patients with GCS-M 1–3 and PHR ≥ 75 bpm had the highest chance of IH (77%), while patients with neither of these risk factors had the lowest chance (29%). The in-hospital mortality rate in the IH and non-IH groups was 44% and 26%, respectively (P = 0.138). GCS-M 1–3, higher PHR, and larger amount of intraoperative blood loss were the risk factors associated with IH during DC procedure in TBI patients. Patients who have these risk factors should be closely monitored and the attending physician be ready to apply prompt resuscitation and treatment for IH.
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ISSN:1878-8750
1878-8769
DOI:10.1016/j.wneu.2022.03.102