Search Results - "Saeed, Mohd"
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The significance of renewable energy, globalization, and agriculture on sustainable economic growth and green environment: Metaphorically, a two‐sided blade
Published in Natural resources forum (01-08-2024)“…The study investigates the effects of renewable energy, globalization, and agriculture on long‐term economic progress and the environment. Using a data set of…”
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Identification of imidazole-based small molecules to combat cognitive disability caused by Alzheimer’s disease: A molecular docking and MD simulations based approach
Published in Computational biology and chemistry (01-10-2024)“…Alzheimer's disease (AD) is a chronic neurodegenerative disorder that is the primary cause of dementia. It is characterised by the gradual loss of brain cells,…”
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Glycyrrhizin Mediates Downregulation of Notch Pathway Resulting in Initiation of Apoptosis and Disruption in the Cell Cycle Progression in Cervical Cancer Cells
Published in Nutrition and cancer (07-02-2022)“…Growing emphasis on exploring the antiproliferative potential of natural compounds has gathered momentum for the formulation of anticancer drugs. In the…”
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Tomatidine and Patchouli Alcohol as Inhibitors of SARS-CoV-2 Enzymes (3CLpro, PLpro and NSP15) by Molecular Docking and Molecular Dynamics Simulations
Published in International journal of molecular sciences (02-10-2021)“…Considering the current dramatic and fatal situation due to the high spreading of SARS-CoV-2 infection, there is an urgent unmet medical need to identify novel…”
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Updates on the anticancer potential of garlic organosulfur compounds and their nanoformulations: Plant therapeutics in cancer management
Published in Frontiers in pharmacology (20-03-2023)“…Garlic ( L.) possesses numerous pharmacological potential, including antibacterial, antiarthritic, antithrombotic, anticancer, hypoglycemic, and hypolipidemic…”
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Interaction of Ectodomain of Respiratory Syncytial Virus G Protein with TLR2/ TLR6 Heterodimer: An In vitro and In silico Approach to Decipher the Role of RSV G Protein in Pro-inflammatory Response against the Virus
Published in Current pharmaceutical design (01-01-2021)“…Human respiratory syncytial virus (RSV) has been shown to be linked with various forms of respiratory diseases, such as common cold and lower respiratory tract…”
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Identification of Persuasive Antiviral Natural Compounds for COVID-19 by Targeting Endoribonuclease NSP15: A Structural-Bioinformatics Approach
Published in Molecules (Basel, Switzerland) (01-12-2020)“…SARS-CoV-2 is a positive-stranded RNA virus that bundles its genomic material as messenger-sense RNA in infectious virions and replicates these genomes through…”
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Design of a high precision CMOS programmable gain and data rate delta sigma ADC
Published in Analog integrated circuits and signal processing (01-08-2023)“…This paper presents a general purpose high precision Delta Sigma ( Δ Σ ) ADC with a common mode rejection of 100 dB, developed for data acquisition of sensors…”
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Metallic and metal oxide-derived nanohybrid as a tool for biomedical applications
Published in Biomedicine & pharmacotherapy (01-11-2022)“…Nanotechnology covers a variety of scientific areas including chemistry, material science, physics, biomedicine, biology, and engineering. Metal nanohybrid…”
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Natural therapeutics and nutraceuticals for lung diseases: Traditional significance, phytochemistry, and pharmacology
Published in Biomedicine & pharmacotherapy (01-06-2022)“…Lung diseases including chronic obstructive pulmonary disease (COPD), infections like influenza, acute respiratory distress syndrome (ARDS), asthma and…”
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Assessment of Antidiabetic Activity of the Shikonin by Allosteric Inhibition of Protein-Tyrosine Phosphatase 1B (PTP1B) Using State of Art: An In Silico and In Vitro Tactics
Published in Molecules (Basel, Switzerland) (30-06-2021)“…is a multifactorial disease that affects both developing and developed countries and is a major public health concern. Many synthetic drugs are available in…”
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Oxidation, glycation and glycoxidation—The vicious cycle and lung cancer
Published in Seminars in cancer biology (01-04-2018)“…The combine effect of oxidative and glycative stress predisposed to glycoxidation, and their outcomes that play critical role in lung cancer have been examined…”
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Beyond antibiotics: CRISPR/Cas9 triumph over biofilm-associated antibiotic resistance infections
Published in Frontiers in cellular and infection microbiology (05-07-2024)“…A complex structure known as a biofilm is formed when a variety of bacterial colonies or a single type of cell in a group sticks to a surface. The…”
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Carvacrol Induced Program Cell Death and Cell Cycle Arrest in Androgen-Independent Human Prostate Cancer Cells via Inhibition of Notch Signaling
Published in Anti-cancer agents in medicinal chemistry (01-01-2019)“…Several studies have revealed that abnormal activation of Notch signaling is closely related with the development and progression of prostate cancer. Although…”
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Biomedical and Antioxidant Potentialities in Chilli: Perspectives and Way Forward
Published in Molecules (Basel, Switzerland) (27-09-2022)“…Worldwide, since ages and nowadays, traditional medicine is well known, owing to its biodiversity, which immensely contributed to the advancement and…”
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Exploring novel natural compound-based therapies for Duchenne muscular dystrophy management: insights from network pharmacology, QSAR modeling, molecular dynamics, and free energy calculations
Published in Frontiers in pharmacology (02-10-2024)“…Muscular dystrophies encompass a heterogeneous group of rare neuromuscular diseases characterized by progressive muscle degeneration and weakness. Among these,…”
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Empirical Relationship Between Creativity and Carbon Intensity: A Case of Saudi Arabia
Published in Frontiers in environmental science (01-03-2022)“…This paper investigates the impact of GDP, renewable energy consumption, patents, and innovation on carbon intensity in Saudi Arabia. For this purpose, we use…”
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Receptor-Based Pharmacophore Modeling in the Search for Natural Products for COVID-19 Mpro
Published in Molecules (Basel, Switzerland) (11-03-2021)“…Considering the urgency of the COVID-19 pandemic, we developed a receptor-based pharmacophore model for identifying FDA-approved drugs and hits from natural…”
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Isolation of anticancer bioactive secondary metabolites from the sponge-derived endophytic fungi Penicillium sp. and in-silico computational docking approach
Published in Frontiers in microbiology (02-10-2023)“…Introduction Fungus-derived secondary metabolites are fascinating with biomedical potential and chemical diversity. Mining endophytic fungi for drug candidates…”
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Organosulphur Compounds Induce Apoptosis and Cell Cycle Arrest in Cervical Cancer Cells via Downregulation of HPV E6 and E7 Oncogenes
Published in Anti-cancer agents in medicinal chemistry (01-01-2021)“…The quest for strong, safe and cost-effective natural antiproliferative agents that could reduce cancer has been the focus now a days. In this regard, the…”
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