Search Results - "Saeed, MB"
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Two sides of the coin: Cytoskeletal regulation of immune synapses in cancer and primary immune deficiencies
Published in International review of cell and molecular biology (2020)“…Actin cytoskeleton remodeling facilitates and fine-tunes diverse cellular processes. Cells have evolved to use the same building blocks of actin monomers to…”
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SHP-1 localization to the activating immune synapse promotes NK cell tolerance in MHC class I deficiency
Published in Science signaling (11-04-2023)“…Natural killer (NK) cells recognize virally infected cells and tumors. NK cell function depends on balanced signaling from activating receptors, recognizing…”
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Overactive WASp in X-linked neutropenia leads to aberrant B-cell division and accelerated plasma cell generation
Published in Journal of allergy and clinical immunology (01-03-2022)“…B-cell affinity maturation in germinal center relies on regulated actin dynamics for cell migration and cell-to-cell communication. Activating mutations in the…”
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Higher Incidence of B Cell Malignancies in Primary Immunodeficiencies: A Combination of Intrinsic Genomic Instability and Exocytosis Defects at the Immunological Synapse
Published in Frontiers in immunology (09-11-2020)“…Congenital defects of the immune system called primary immunodeficiency disorders (PID) describe a group of diseases characterized by a decrease, an absence,…”
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Journey to the Center of the Cell Cytoplasmic and Nuclear Actin in Immune Cell Functions
Published in Frontiers in cell and developmental biology (2021)Get full text
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Journey to the Center of the Cell: Cytoplasmic and Nuclear Actin in Immune Cell Functions
Published in Frontiers in cell and developmental biology (2021)“…Actin cytoskeletal dynamics drive cellular shape changes, linking numerous cell functions to physiological and pathological cues. Mutations in actin regulators…”
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SHP-1 expression and localization are associated with functional education of murine natural killer cells
Published in SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2021)Get full text
Conference Proceeding -
8
Overactive WASp in X-linked neutropenia leads to aberrant B-cell division and accelerated plasma cell generation
Published in SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2021)Get full text
Conference Proceeding -
9
A Technical Point for Split Thickness Skin Graft: This Side Up
Published in Plastic and reconstructive surgery. Global open (01-04-2019)Get full text
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Finite element analysis of mechanical properties of woven composites through a micromechanics model
Published in Science and engineering of composite materials (01-01-2017)“…In a woven fabric composite, arrangement and behavior of the fibers contained in the yarn and the yarns themselves lead to an intricate deformation mechanism…”
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Constitutive activation of WASp leads to abnormal cytotoxic cells with increased granzyme B and degranulation response to target cells
Published in JCI insight (22-03-2021)“…X-linked neutropenia (XLN) is caused by gain-of-function mutations in the actin regulator Wiskott-Aldrich Syndrome protein (WASp). XLN patients have reduced…”
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The role of fibroblast growth factor-23 in left atrial volume
Published in The American heart journal (01-05-2013)“…Decreased FGF-23 concentrations during vitamin D replacement5 may play the role in the reduction of left atrial volume…”
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Wellens' syndrome and clinical significance of T-wave inversion in anterior precordial leads
Published in The American journal of emergency medicine (01-02-2013)Get full text
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14
Therapeutic hypothermia and effects on coagulopathy
Published in The American journal of emergency medicine (01-07-2012)Get full text
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Electrocardiographic changes in tricyclic antidepressant toxicity
Published in The American journal of emergency medicine (01-04-2013)“…The main pathophysiology of cardiac conduction abnormalities is fast sodium channel inhibition in the His-Purkinje system as well as the atrial and ventricular…”
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A case of childhood vasculitis presenting in adulthood
Published in The American journal of emergency medicine (2013)Get full text
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Syncope in Brugada syndrome type 3: an electrocardiographic lesson
Published in The American journal of emergency medicine (01-03-2013)“…Patients with Brugada syndrome do not have ventricular extrasystoles or nonsustained ventricular tachycardia at Holter monitoring. [...]the therapeutic…”
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18
Achillon versus open surgery in acute Achilles tendon repair
Published in Foot and ankle surgery (01-10-2018)“…Highlights • Complications following surgery are significantly reduced in the Achillon repairs. • Re-rupture rates are similar between the two groups. • No…”
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