Search Results - "Saeed, Aamer"
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Synthetic approaches, functionalization and therapeutic potential of quinazoline and quinazolinone skeletons: The advances continue
Published in European journal of medicinal chemistry (27-01-2015)“…The presence of N-heterocycles as an essential structural motif in a variety of biologically active substances has stimulated the development of new strategies…”
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Recent advances in the structural library of functionalized quinazoline and quinazolinone scaffolds: Synthetic approaches and multifarious applications
Published in European journal of medicinal chemistry (09-04-2014)“…Drug development has been a principal driving force in the rapid maturation of the field of medicinal chemistry during the past several decades. During this…”
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Chemical Insights Into the Synthetic Chemistry of Quinazolines: Recent Advances
Published in Frontiers in chemistry (14-01-2021)“…In medicinal chemistry, one of the most significant heterocyclic compounds are quinazolines, possessing broad range of biological properties such as…”
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Natural isocoumarins: Structural styles and biological activities, the revelations carry on
Published in Phytochemistry (Oxford) (01-01-2021)“…Isocoumarins and dihydroisocoumarins are lactonic phytochemicals plentiful in microbes and higher plants. These are an amazing small scaffolds consecrated with…”
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Contemporary Developments in Ferrocene Chemistry: Physical, Chemical, Biological and Industrial Aspects
Published in Molecules (Basel, Switzerland) (30-07-2023)“…Ferrocenyl-based compounds have many applications in diverse scientific disciplines, including in polymer chemistry as redox dynamic polymers and dendrimers,…”
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Recent advances in the synthesis, biological activities and various applications of ferrocene derivatives
Published in Applied organometallic chemistry (01-08-2017)“…Ferrocene derivatives constitute an important class of organometallic compounds with not only an extensive range of biological activities but also diverse…”
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Recent developments in synthetic chemistry and biological activities of pyrazole derivatives
Published in Journal of chemical sciences (Bangalore, India) (01-08-2019)“…Pyrazole, a five-membered heterocycle containing two nitrogen atoms, is extensively found as a core framework in a huge library of heterocyclic compounds that…”
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Recent trends in chemistry, structure, and various applications of 1-acyl-3-substituted thioureas: a detailed review
Published in RSC advances (22-04-2022)“…The interest in acyl thioureas has continually been escalating owing to their extensive applications in diverse fields, such as synthetic precursors of new…”
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A Novel Test Rig for the Investigation of Ball Bearing Cage Friction
Published in Tribology transactions (03-09-2021)“…This article presents a novel experimental test rig for the investigation of friction between a ball and cage of a deep groove ball bearing (DGBB). The…”
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Lubrication, Flow Visualization, and Multiphase CFD Modeling of Ball Bearing Cage
Published in Tribology transactions (25-10-2022)“…The objective of this study was to experimentally and analytically investigate the lubrication condition and visualize the fluid flow in a ball bearing cage…”
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Marine Natural Products: A Source of Novel Anticancer Drugs
Published in Marine drugs (23-08-2019)“…Cancer remains one of the most lethal diseases worldwide. There is an urgent need for new drugs with novel modes of action and thus considerable research has…”
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In Situ Visualization and Analysis of Oil Starvation in Ball Bearing Cages
Published in Tribology transactions (03-09-2023)“…This article presents an investigation into oil starvation in different cage pocket shapes of a horizontally mounted ball bearing. A counter-rotating angular…”
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Development of Multi-concentration Cu:Ag Bimetallic Nanoparticles as a Promising Bactericidal for Antibiotic-Resistant Bacteria as Evaluated with Molecular Docking Study
Published in Nanoscale research letters (22-05-2021)“…The present study is concerned with evaluating the influence of various concentrations of Ag within Cu:Ag bimetallic nanoparticles developed for use as a…”
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Tropylium Ion, an Intriguing Moiety in Organic Chemistry
Published in Molecules (Basel, Switzerland) (15-05-2023)“…The tropylium ion is a non-benzenoid aromatic species that works as a catalyst. This chemical entity brings about a large number of organic transformations,…”
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Design, synthesis, kinetic mechanism and molecular docking studies of novel 1-pentanoyl-3-arylthioureas as inhibitors of mushroom tyrosinase and free radical scavengers
Published in European journal of medicinal chemistry (01-12-2017)“…A series of novel 1-pentanoyl-3-arylthioureas was designed as new mushroom tyrosinase inhibitors and free radical scavengers. The title compounds were obtained…”
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Synthesis, characterization, antimicrobial, antioxidant and computational evaluation of N-acyl-morpholine-4-carbothioamides
Published in Molecular diversity (01-05-2021)“…The present research paper reports the convenient synthesis, successful characterization, in vitro antibacterial, antifungal, antioxidant potency and…”
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Chemistry and Pharmacology of Fluorinated Drugs Approved by the FDA (2016–2022)
Published in Pharmaceuticals (Basel, Switzerland) (01-08-2023)“…Fluorine is characterized by high electronegativity and small atomic size, which provide this molecule with the unique property of augmenting the potency,…”
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Synthesis and characterization of high wash fastness novel azo reactive dyes incorporating aromatic bridged diamines
Published in Arabian journal of chemistry (01-01-2018)“…A new series of azo reactive dyes containing free chlorine atoms have been synthesized. The synthetic methodology involves the diazotization of 4′4-diamino…”
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Design, Synthesis, QSAR Studies, and Molecular Modeling of Some Novel Bis Methyl 2-[3-(benzo[d]thiazol-2-yl)-2-terephthaloyl-bis-4-oxo-thiazolidin- 5-ylidene]acetates and Screening of their Antioxidant and Enzyme Inhibition Properties
Published in Current organic synthesis (01-01-2024)“…Benzothiazolamine-based bisthiourea precursors were prepared in good yields. These bisthiourea derivatives were cyclized into symmetrical Bis Methyl…”
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Synthesis, single crystal X-ray structure determination, Hirshfeld surface analysis, crystal voids studies, and density functional theory calculations of N-carbamothioylbenzamide and 1,3,5-triazinane-2,4,6-trithione co-crystal
Published in Structural chemistry (01-02-2024)“…The current research presents simple synthesis, single crystal X-ray structure determination, Hirshfeld surface (HS) analysis, crystal voids studies, and…”
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