Search Results - "Saedtler, Marco"

Cytotoxic properties of the alkaloid rutaecarpine and its oligocyclic derivatives and chemical modifications to enhance water-solubility by Huang, Guozheng, Drakopoulos, Antonios, Saedtler, Marco, Zou, Huijuan, Meinel, Lorenz, Heilmann, Jörg, Decker, Michael

“…[Display omitted] The alkaloid rutaecarpine and its derivatives have been described as cytotoxic and hold potential as antitumor agents. Nevertheless, their…”
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Bioinspired co-crystals of Imatinib providing enhanced kinetic solubility by Reggane, Maude, Wiest, Johannes, Saedtler, Marco, Harlacher, Cornelius, Gutmann, Marcus, Zottnick, Sven H., Piechon, Philippe, Dix, Ina, Müller-Buschbaum, Klaus, Holzgrabe, Ulrike, Meinel, Lorenz, Galli, Bruno

“…[Display omitted] Realizing the full potential of co-crystals enhanced kinetic solubility demands a comprehensive understanding of the mechanisms of…”
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Mapping the pharmaceutical design space by amorphous ionic liquid strategies by Wiest, Johannes, Saedtler, Marco, Balk, Anja, Merget, Benjamin, Widmer, Toni, Bruhn, Heike, Raccuglia, Marc, Walid, Elbast, Picard, Franck, Stopper, Helga, Dekant, Wolfgang, Lühmann, Tessa, Sotriffer, Christoph, Galli, Bruno, Holzgrabe, Ulrike, Meinel, Lorenz

“…Poor water solubility of drugs fuels complex formulations and jeopardizes patient access to medication. Simplifying these complexities we systematically…”
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Azobenzene derivatives with activity against drug‐resistant Candida albicans and Candida auris by Raschig, Martina, Ramírez‐Zavala, Bernardo, Wiest, Johannes, Saedtler, Marco, Gutmann, Marcus, Holzgrabe, Ulrike, Morschhäuser, Joachim, Meinel, Lorenz

“…Increasing resistance against antimycotic drugs challenges anti‐infective therapies today and contributes to the mortality of infections by drug‐resistant…”
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Geometrical and Structural Dynamics of Imatinib within Biorelevant Colloids by Wiest, Johannes, Saedtler, Marco, Böttcher, Bettina, Grüne, Marvin, Reggane, Maude, Galli, Bruno, Holzgrabe, Ulrike, Meinel, Lorenz

“…Solubilization of lipophilic drugs is essential for efficient uptake. We detail the solubilization of imatinib in simulated gastrointestinal fluids containing…”
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Investigations into neuroprotectivity, stability, and water solubility of 7‐O‐cinnamoylsilibinin, its hemisuccinate and dehydro derivatives by Schramm, Simon, Gunesch, Sandra, Lang, Florian, Saedtler, Marco, Meinel, Lorenz, Högger, Petra, Decker, Michael

“…Derivatives of the recently described potent neuroprotective 7‐O‐cinnamoylsilibinin ester were prepared: its hemisuccinate to improve water solubility and the…”
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Controlling Supramolecular Structures of Drugs by Light by Wiest, Johannes, Kehrein, Josef, Saedtler, Marco, Schilling, Klaus, Cataldi, Eleonora, Sotriffer, Christoph A, Holzgrabe, Ulrike, Rasmussen, Tim, Böttcher, Bettina, Cronin-Golomb, Mark, Lehmann, Matthias, Jung, Nathalie, Windbergs, Mike, Meinel, Lorenz

“…Controlling physicochemical properties of light-unresponsive drugs, by light, prima facie, a paradox approach. We expanded light control by ion pairing…”
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Antibacterial Anacardic Acid Derivatives by Saedtler, Marco, Förtig, Niclas, Ohlsen, Knut, Faber, Franziska, Masota, Nelson, Kowalick, Kristin, Holzgrabe, Ulrike, Meinel, Lorenz

“…We report on the antibacterial activity of five phenolic lipids derived from anacardic acid characterized by increasing alkyl chain lengths with 6, 8, 10, 12,…”
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