Search Results - "Sadowska, B"

Ischemia–reperfusion impairs blood–brain barrier function and alters tight junction protein expression in the ovine fetus by Chen, X, Threlkeld, S.W, Cummings, E.E, Juan, I, Makeyev, O, Besio, W.G, Gaitanis, J, Banks, W.A, Sadowska, G.B, Stonestreet, B.S

“…Highlights ► Blood–brain barrier permeability increases after ischemia–reperfusion in the fetus. ► Increases in permeability ( Ki ) change as function of the…”
Get full text

Neutralizing anti-interleukin-1β antibodies modulate fetal blood–brain barrier function after ischemia by Chen, Xiaodi, Sadowska, Grazyna B, Zhang, Jiyong, Kim, Jeong-Eun, Cummings, Erin E, Bodge, Courtney A, Lim, Yow-Pin, Makeyev, Oleksandr, Besio, Walter G, Gaitanis, John, Threlkeld, Steven W, Banks, William A, Stonestreet, Barbara S

“…Abstract We have previously shown that increases in blood–brain barrier permeability represent an important component of ischemia–reperfusion related brain…”
Get full text

Ischemia reduces inter‐alpha inhibitor proteins in the brain of the ovine fetus by Spasova, Mariya S., Chen, Xiaodi, Sadowska, Grazyna B., Horton, Edward R., Lim, Yow‐Pin, Stonestreet, Barbara S.

“…ABSTRACT Hypoxic‐ischemic (HI) brain injury is a major cause of neurological abnormalities in the perinatal period. Inflammation contributes to the evolution…”
Get full text

Ischemic-Reperfusion Injury Increases Matrix Metalloproteinases and Tissue Metalloproteinase Inhibitors in Fetal Sheep Brain by Chen, Xiaodi, Patra, Aparna, Sadowska, Grazyna B, Stonestreet, Barbara S

“…Hypoxic-ischemic brain injury is a leading cause of neurodevelopmental morbidities in preterm and full-term infants. Blood-brain barrier dysfunction represents…”
Get more information

Maternal glucocorticoid exposure alters tight junction protein expression in the brain of fetal sheep by Sadowska, Grazyna B, Malaeb, Shadi N, Stonestreet, Barbara S

“…We examined the expression of tight junction (TJ) proteins in the cerebral cortex, cerebellum, and spinal cord of fetuses after maternal treatment with single…”
Get more information

Effects of interleukin-6 on the expression of tight junction proteins in isolated cerebral microvessels from yearling and adult sheep by Cohen, Susan S, Min, May, Cummings, Erin E, Chen, Xiaodi, Sadowska, Grazyna B, Sharma, Surendra, Stonestreet, Barbara S

“…The blood-brain barrier is a selective diffusion barrier between brain parenchyma and the intravascular compartment. Tight junctions are integral components of…”
Get more information

Ontogeny of inter-alpha inhibitor proteins in ovine brain and somatic tissues by Spasova, Mariya S, Sadowska, Grazyna B, Threlkeld, Steven W, Lim, Yow-Pin, Stonestreet, Barbara S

“…Inter-alpha inhibitor proteins (IAIPs) found in relatively high concentrations in human plasma are important in inflammation. IAIPs attenuate brain damage in…”
Get more information

Ontogeny of tight junction protein expression in the ovine cerebral cortex during development by Sadowska, G.B, Ahmedli, N, Chen, X, Stonestreet, B.S

“…Highlights • Claudin-3, -12 and JAM-A are expressed as very early in ovine gestation. • Claudin-3, -12 and JAM-A each exhibit differential developmental…”
Get full text

Influence of SFRC Layer on Deflections and Cracks of Composite RC Slab by Sadowska-Buraczewska, B.

“…This paper presents an experimental analysis of flexural capacity and deformability of structural concrete slabs prepared as composite members consisting of…”
Get full text

Maternal treatment with glucocorticoids modulates gap junction protein expression in the ovine fetal brain by Sadowska, G.B, Stonestreet, B.S

“…Highlights • Maternal glucocorticoids increase gap junction proteins in fetal brain. • Gap junction proteins are differentially regulated by maternal…”
Get full text

The influence of Lactobacillus acidophilus-derived surfactants on staphylococcal adhesion and biofilm formation by Walencka, E., Różalska, S., Sadowska, B., Różalska, B.

“…The ability of surfactants obtained from three Lactobacillus acidophilus strains to inhibit Staphylococcus aureus and S. epidermidis biofilms was evaluated…”
Get full text

Antimicrobial and anti-biofilm properties of new taxodione derivative from hairy roots of Salvia austriaca by Kuźma, Ł., Wysokińska, H., Różalski, M., Budzyńska, A., Więckowska-Szakiel, M., Sadowska, B., Paszkiewicz, M., Kisiel, W., Różalska, B.

“…The aim of the present report was to evaluate antimicrobial/anti-biofilm activity of 7-(2-oxohexyl)-taxodione, a novel taxodione derivative isolated from…”
Get full text

Ovine proinflammatory cytokines cross the murine blood-brain barrier by a common saturable transport mechanism by Threlkeld, Steven W, Lynch, Jessica L, Lynch, Kristin M, Sadowska, Grazyna B, Banks, William A, Stonestreet, Barbara S

“…The cytokines interleukin (IL)-1beta and IL-6 are modulators of the neuroimmune axis and have been implicated in neuronal cell death cascades after ischemia or…”
Get more information

Ontogeny and the effects of exogenous and endogenous glucocorticoids on tight junction protein expression in ovine cerebral cortices by Duncan, Anna R, Sadowska, Grazyna B, Stonestreet, Barbara S

“…Abstract Maternal glucocorticoid treatment reduces blood–brain permeability early, but not late in fetal development, and pretreatment with glucocorticoids…”
Get full text

Comparative effects of glucose- and mannitol-induced osmolar stress on blood-brain barrier function in ovine fetuses and lambs by Stonestreet, Barbara S, Sadowska, Grazyna B, Hanumara, R Choudary, Petrache, Mihaela, Petersson, Katherine H, Patlak, Clifford S

“…We examined the effects of hyperglycemic hyperosmolality on blood-brain barrier (BBB) permeability during development. We hypothesized that the barrier becomes…”
Get full text

Bacteria competing with the adhesion and biofilm formation by Staphylococcus aureus by Sadowska, B., Walencka, E., Wieckowska-Szakiel, M., Różalska, B.

“…The activity of antagonistic substances produced by Pseudomonas aeruginosa and Lactobacillus acidophilus against the planktonic and sessile populations of…”
Get full text

Ontogeny of connexin 32 and 43 expression in the cerebral cortices of ovine fetuses, newborns, and adults by Sadowska, Grazyna B, Stopa, Edward G, Stonestreet, Barbara S

“…Abstract Gap junctions are specialized membrane structures that mediate intercellular communication and facilitate passage of ions and small molecules between…”
Get full text

Effects of maternal treatment with corticosteroids on tight junction protein expression in the cerebral cortex of the ovine fetus with and without exposure to in utero brain ischemia by Malaeb, Shadi N, Sadowska, Grazyna B, Stonestreet, Barbara S

“…Abstract Maternal treatment with corticosteroids reduces blood–brain barrier permeability in premature ovine fetuses and the incidence of intraventricular…”
Get full text

Anti‐IL‐6 neutralizing antibody modulates blood‐brain barrier function in the ovine fetus by Zhang, Jiyong, Sadowska, Grazyna B., Chen, Xiaodi, Park, Seon Yeong, Kim, Jeong‐Eun, Bodge, Courtney A., Cummings, Erin, Lim, Yow‐Pin, Makeyev, Oleksandr, Besio, Walter G., Gaitanis, John, Banks, William A., Stonestreet, Barbara S.

“…ABSTRACT Impaired blood‐brain barrier function represents an important component of hypoxic‐ischemic brain injury in the perinatal period. Proinflammatory…”
Get full text

Exogenous and endogenous corticosteroids modulate blood-brain barrier development in the ovine fetus by Stonestreet, B S, Sadowska, G B, McKnight, A J, Patlak, C, Petersson, K H

“…We previously reported decreases in blood-brain barrier permeability in the ovine fetus at 80% of gestation after antenatal corticosteroids and shown that…”
Get more information