Search Results - "Sadler, A J"

Structure and function of the protein kinase R by Sadler, A J, Williams, B R G

“…The protein kinase R (PKR) is an intracellular sensor of stress, exemplified by viral infection. Double-stranded (ds) RNA produced during viral replication…”
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Use of global gene expression patterns in mechanistic studies of oestrogen action in MCF7 human breast cancer cells by Sadler, A.J., Pugazhendhi, D., Darbre, P.D.

“…Over the years, the MCF7 human breast cancer cell line has provided a model system for the study of cellular and molecular mechanisms in oestrogen regulation…”
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Comparison of the global gene expression profiles produced by methylparaben, n-butylparaben and 17β-oestradiol in MCF7 human breast cancer cells by Pugazhendhi, D., Sadler, A. J., Darbre, P. D.

“…Since the alkyl esters of p‐hydroxybenzoic acid (parabens) can be measured intact in the human breast and possess oestrogenic properties, it has been suggested…”
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Changes in oestrogen receptor-α and -β during progression to acquired resistance to tamoxifen and fulvestrant (Faslodex, ICI 182,780) in MCF7 human breast cancer cells by Shaw, L.E., Sadler, A.J., Pugazhendhi, D., Darbre, P.D.

“…Cell culture models of antioestrogen resistance often involve applying selective pressures of oestrogen deprivation simultaneously with addition of tamoxifen…”
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Non-attendance at diabetic retinal screening in Te Tai Tokerau, Northland, Aotearoa New Zealand by Wolpert, Laura E, Sadler, Christopher Hja, Watts, Andrew R, Dalziel, David M

“…To explore socio-demographic characteristics of non-attenders at diabetic retinal screening. A retrospective, register-based cross-sectional analysis of 10,275…”
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A simple experimental model for hydrophobic interactions in proteins by Lawson, E Q, Sadler, A J, Harmatz, D, Brandau, D T, Micanovic, R, MacElroy, R D, Middaugh, C R

“…The compound N-cyclohexyl-2-pyrrolidone contains a substantial apolar region as well as a peptide bond-like moiety. This solvent, therefore, provides a useful…”
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Protein conformation and reversed-phase high-performance liquid chromatography by Sadler, A J, Micanovic, R, Katzenstein, G E, Lewis, R V, Middaugh, C R

“…The structure of a series of proteins has been investigated by circular dichroism, fluorescence and visible spectroscopy as well as by differential scanning…”
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Proglacial Lake-Ice Conveyors: A New Mechanism for Deposition of Drift in Polar Environments by Hendy, C. H., Sadler, A. J., Denton, G. H., Hall, B. L.

“…Interpretation of sediments in the floors of valleys opening into western McMurdo Sound has been so problematic that it has hindered understanding of the late…”
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Decrease in the protein kinase C-catalyzed phosphorylation of an endogenous lung protein (Mr 36000) following treatment of mice with the tumor-modulatory agent butylated hydroxytoluene by MALKINSON, A. M, BEER, D. S, SADLER, A. J, COFFMAN, D. S

“…Butylated hydroxytoluene (BHT) causes transient lung damage in mice, and it can either inhibit or enhance carcinogen induction of tumors in internal organs,…”
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Near-infrared photoacoustic spectroscopy of proteins by Sadler, A J, Horsch, J G, Lawson, E Q, Harmatz, D, Brandau, D T, Middaugh, C R

“…A major problem encountered with the use of electronic spectroscopy in the analysis of biological materials in the ultraviolet, visible, and infrared region…”
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Regulation of Actin Dynamics by Protein Kinase R Control of Gelsolin Enforces Basal Innate Immune Defense by Irving, Aaron T., Wang, Die, Vasilevski, Oliver, Latchoumanin, Olivier, Kozer, Noga, Clayton, Andrew H.A., Szczepny, Anette, Morimoto, Hiroyuki, Xu, Dakang, Williams, Bryan R.G., Sadler, Anthony J.

“…Primary resistance to pathogens is reliant on both basal and inducible immune defenses. To date, research has focused upon inducible innate immune responses…”
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Orchestration of the activation of protein kinase R by the RNA-binding motif by Sadler, Anthony J

“…The protein kinase R (PKR) constitutes part of the host antiviral response. PKR activation is regulated by the N-terminus of protein, which encodes tandem…”
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Cerebral asymmetries in inspection time? by Sadler, Andrew J, Deary, Ian J

“…Recent studies have suggested that there are low-level processing asymmetries across the cerebral hemispheres, with a right visual field-left hemisphere…”
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P117 Regulation of actin dynamics by Protein Kinase R control of gelsolin enforces basal innate immune defense by Irving, A.T., Williams, B.R., sadler, A.J.

“…The primary resistance to pathogens is heavily reliant on the innate immune response. This resistance depends upon both basal and inducible defenses…”
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Evaluation of sprinkler application of fungicides for control of potato early blight in Colorado by Franc, G. D., Nnodu, E. C., Harrison, M. D., Sadler, A. J.

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Modified vaccinia virus Ankara can activate NF-kB transcription factors through a double-stranded RNA-activated protein kinase (PKR)-dependent pathway during the early phase of virus replication by Lynch, HE, Ray, CA, Oie, K L, Pollara, J J, Petty, ITD, Sadler, A J, Williams, BRG, Pickup, D J

“…Modified vaccinia virus Ankara (MVA), which is a promising replication-defective vaccine vector, is unusual among the orthopoxviruses in activating NF-B…”
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Comparison of the global gene expression profiles produced by methylparaben, n-butylparaben and 17[beta]-oestradiol in MCF7 human breast cancer cells by Pugazhendhi, D, Sadler, A J, Darbre, P D

“…Since the alkyl esters of p-hydroxybenzoic acid (parabens) can be measured intact in the human breast and possess oestrogenic properties, it has been suggested…”
Get full text

Comparison of the global gene expression profiles produced by methylparaben, n-butylparaben and 17beta-oestradiol in MCF7 human breast cancer cells by Pugazhendhi, D, Sadler, A J, Darbre, P D

“…Since the alkyl esters of p-hydroxybenzoic acid (parabens) can be measured intact in the human breast and possess oestrogenic properties, it has been suggested…”
Get full text

Comparison of the global gene expression profiles produced by methylparaben, n-butylparaben and 17eta-oestradiol in MCF7 human breast cancer cells by Pugazhendhi, D, Sadler, A J, Darbre, P D

“…Since the alkyl esters of p-hydroxybenzoic acid (parabens) can be measured intact in the human breast and possess oestrogenic properties, it has been suggested…”
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Planning in the French health care system--the example of the Assistance Publique de Paris by Sadler, A J

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