Search Results - "Sadile, A"

Behavioral alterations and changes in Ca/calmodulin kinase II levels in the striatum of connexin36 deficient mice by Zlomuzica, A., Viggiano, D., Degen, J., Binder, S., Ruocco, L.A., Sadile, A.G., Willecke, K., Huston, J.P., Dere, E.

“…► We characterized behavioral changes induced by Cx36 deficiency in the mouse. ► We examined acetylcholine esterase (AChE) activity in the striatum of Cx36 KO…”
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Enhanced limbic/impaired cortical-loop connection onto the hippocampus of NHE rats: Application of resting-state functional connectivity in a preclinical ADHD model by Zoratto, F., Palombelli, G.M., Ruocco, L.A., Carboni, E., Laviola, G., Sadile, A.G., Adriani, W., Canese, R.

“…Due to a hyperfunctioning mesocorticolimbic system, Naples-High-Excitability (NHE) rats have been proposed to model for the meso-cortical variant of attention…”
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Neuronal histamine and the interplay of memory, reinforcement and emotions by Dere, E., Zlomuzica, A., De Souza Silva, M.A., Ruocco, L.A., Sadile, A.G., Huston, J.P.

“…The biogenic amine histamine is an important neurotransmitter-neuromodulator in the central nervous system that has been implicated in a variety of biological…”
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Episodic-like and procedural memory impairments in histamine H1 Receptor knockout mice coincide with changes in acetylcholine esterase activity in the hippocampus and dopamine turnover in the cerebellum by Dere, E, Zlomuzica, A, Viggiano, D, Ruocco, L.A, Watanabe, T, Sadile, A.G, Huston, J.P, De Souza-Silva, M.A

“…Abstract We investigated episodic-like (ELM) and procedural memory (PM) in histamine H1 receptor knockout (H1R-KO) mice. In order to relate possible behavioral…”
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Prepuberal intranasal dopamine treatment in an animal model of ADHD ameliorates deficient spatial attention, working memory, amino acid transmitters and synaptic markers in prefrontal cortex, ventral and dorsal striatum by Ruocco, L. A., Treno, C., Gironi Carnevale, U. A., Arra, C., Mattern, C., Huston, J. P., de Souza Silva, M. A., Nikolaus, S., Scorziello, A., Nieddu, M., Boatto, G., Illiano, P., Pagano, C., Tino, A., Sadile, A. G.

“…Intranasal application of dopamine (IN-DA) has been shown to increase motor activity and to release DA in the ventral (VS) and dorsal striatum (DS) of rats…”
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The histamine H1-receptor mediates the motivational effects of novelty by Zlomuzica, A., Viggiano, D., De Souza Silva, M. A., Ishizuka, T., Carnevale, U. A. Gironi, Ruocco, L. A., Watanabe, T., Sadile, A. G., Huston, J. P., Dere, E.

“…Novelty‐induced arousal has motivational effects and can reinforce behavior. The mechanisms by which novelty acts as a reinforcer are unknown. Novelty‐induced…”
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Connexin31.1 deficiency in the mouse impairs object memory and modulates open-field exploration, acetylcholine esterase levels in the striatum, and cAMP response element-binding protein levels in the striatum and piriform cortex by Dere, E, Zheng-Fischhöfer, Q, Viggiano, D, Gironi Carnevale, U.A, Ruocco, L.A, Zlomuzica, A, Schnichels, M, Willecke, K, Huston, J.P, Sadile, A.G

“…Abstract Neuronal gap junctions in the brain, providing intercellular electrotonic signal transfer, have been implicated in physiological and behavioral…”
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Prepuberal subchronic methylphenidate and atomoxetine induce different long-term effects on adult behaviour and forebrain dopamine, norepinephrine and serotonin in Naples High-Excitability rats by Ruocco, L.A., Gironi Carnevale, U.A., Treno, C., Sadile, A.G., Melisi, D., Arra, C., Ibba, M., Schirru, C., Carboni, E.

“…The psychostimulant methylphenidate and the non-stimulant atomoxetine are two approved drugs for attention-deficit hyperactivity disorder (ADHD) therapy. The…”
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Multiple evidence of a segmental defect in the anterior forebrain of an animal model of hyperactivity and attention deficit by Sadile, A.G

“…Molecular biology and microscope imaging techniques were used to map putative neural substrates of hyperactivity and attention deficit in an animal model, the…”
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Galactosylated dopamine enters into the brain, blocks the mesocorticolimbic system and modulates activity and scanning time in Naples high excitability rats by Ruocco, L.A, Viggiano, D, Viggiano, A, Abignente, E, Rimoli, M.G, Melisi, D, Curcio, A, Nieddu, M, Boatto, G, Carboni, E, Gironi Carnevale, U.A, Sadile, A.G

“…Abstract Pathological conditions, such as Parkinson’s disease and attention deficit hyperactivity disorder, have been linked to alterations of specific…”
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Immunization with DISC1 protein in an animal model of ADHD influences behavior and excitatory amino acids in prefrontal cortex and striatum by Ruocco, L. A., Treno, C., Gironi Carnevale, U. A., Arra, C., Boatto, G., Pagano, C., Tino, A., Nieddu, M., Michel, M., Prikulis, I., Carboni, E., de Souza Silva, M. A., Huston, J. P., Sadile, A. G., Korth, C.

“…The Disrupted - in - schizophrenia 1 (DISC1) gene is involved in vulnerability to neuropsychiatric disorders. Naples high-excitability (NHE) rat model…”
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Transcription factor expression, RNA synthesis and NADPH-diaphorase across the rat brain and exposure to spatial novelty by Romanelli, P., Di Matteo, L., Cobellis, G., Varriale, B., Menegazzi, M., Gironi Carnevale, U.A., Ruocco, L.A., Sadile, A.G.

“…The molecular hypothesis of learning and memory processes is based on changes in synaptic weights in neural networks. Aim of this study was to map neural…”
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Elevated forebrain excitatory l-glutamate, l-aspartate and d-aspartate in the Naples high-excitability rats by Ruocco, L.A., Carnevale, U.A. Gironi, Sadile, A.G., Sica, A., Arra, C., Di Maio, A., Topo, E., D’Aniello, A.

“…The Naples high-excitability (NHE) rats are thought to model the mesocortical variant of attention-deficit hyperactivity disorder (ADHD). The aim of this study…”
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Histamine H 1 receptor knockout mice exhibit impaired spatial memory in the eight‐arm radial maze by Zlomuzica, A, Ruocco, LA, Sadile, AG, Huston, JP, Dere, E

“…Background and purpose:  In the mammalian brain, histaminergic neurotransmission is mediated by the postsynaptic histamine H 1 and H 2 receptors and the…”
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Non-selective attention in a rat model of hyperactivity and attention deficit: subchronic methylphenydate and nitric oxide synthesis inhibitor treatment by Aspide, R, Fresiello, A, de Filippis, G, Gironi Carnevale, U.A, Sadile, A.G

“…The involvement of dopamine (DA) and nitric oxide (NO) in the process of non-selective attention (NSA) to environmental stimuli has been investigated in the…”
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Differential prepuberal handling modifies behaviour and excitatory amino acids in the forebrain of the Naples High-Excitability rats by Ruocco, L.A., Carnevale, U.A. Gironi, Sica, A., Arra, C., Topo, E., Di Giovanni, M., D’Aniello, A., Sadile, A.G.

“…Naples High-Excitability (NHE) rats model the mesocortical variant of Attention-Deficit Hyperactivity Disorder (ADHD). Recently, a high level of excitatory…”
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Galactosilated dopamine increases attention without reducing activity in C57BL/6 mice by Ruocco, L.A., Viggiano, D., Pignatelli, M., Iannaccone, T., Rimoli, M.G., Melisi, D., Curcio, A., De Lucia, S., Carboni, E., Carnevale, U.A. Gironi, de Caprariis, P., Sadile, A.G.

“…Different strategies can be used to carry dopamine into the brain such as l-Dopa precursors or galactosilated form of DA (GAL-DA). The aim of this study was to…”
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Histamine H1 receptor knockout mice exhibit impaired spatial memory in the eight‐arm radial maze by Zlomuzica, A, Ruocco, LA, Sadile, AG, Huston, JP, Dere, E

“…Background and purpose:  In the mammalian brain, histaminergic neurotransmission is mediated by the postsynaptic histamine H1 and H2 receptors and the…”
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Involvement of norepinephrine in the control of activity and attentive processes in animal models of attention deficit hyperactivity disorder by Viggiano, D, Ruocco, L A, Arcieri, S, Sadile, A G

“…Functional and morphological studies in children affected by Attention Deficit Hyperactivity Disorder (ADHD) suggest a prefrontal cortex (PFc) dysfunction…”
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Excitatory amino acids in the forebrain of the Naples high-excitability rats: neurochemical and behavioural effects of subchronic d-aspartate and its diethyl ester prodrug by Ruocco, L.A., Di Pizzo, A., Gironi Carnevale, U.A., Murolo, M., Sadile, A.G., Arra, C., Topo, E., D’Aniello, A., Curcio, A., Melisi, D., Rimoli, M.G.

“…The excitatory amino acids (EAA) l-glutamate ( l-Glu), l-aspartate ( l-Asp) and d-aspartate ( d-Asp) are thought to play a neurotransmitter/neuromodulator role…”
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