Search Results - "Sadighi Gilani, Mohammad Ali"
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1
Whole genome sequencing identifies a homozygous splicing variant in TDRKH segregating with non‐obstructive azoospermia in an Iranian family
Published in Clinical genetics (01-11-2024)“…Non‐obstructive azoospermia (NOA) resulting from primary spermatogenic failure represents one of the most severe forms of male infertility, largely because…”
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2
Sperm Retrieval in Non-azoospermic Patients with Persistent Ejaculation Dysfunction
Published in Journal of reproduction & infertility (01-07-2022)“…Infertility is a common disease that affects 15 to 20% of couples at some point in their lives. Among infertile couples, male factor accounts for 50% of…”
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3
Identification of a missense variant in CLDN2 in obstructive azoospermia
Published in Journal of human genetics (01-10-2019)“…Obstructive azoospermia (OA), defined as an obstruction in any region of the male genital tract, accounts for 40% of all azoospermia cases. Of all OA cases,…”
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4
The expression of Cysteine-Rich Secretory Protein 2 (CRISP2) and miR-582-5p in seminal plasma fluid and spermatozoa of infertile men
Published in Gene (10-03-2020)“…•CRISP2 expression in seminal plasma fluid showed a significant decrease in TAZ, AZ, and TZ groups.•CRISP2 expression in spermatozoa showed a significant…”
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5
Vasectomy reversal: Unilateral versus bilateral vasovasostomy
Published in Andrologia (01-10-2021)“…The aim of this study was to evaluate and compare the efficiencies of unilateral and bilateral vasovasostomies as the vasectomy reversal procedures. A total of…”
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Comparison of Sperm Retrieval and Intracytoplasmic Sperm Injection Outcome in Patients With and Without Klinefelter Syndrome
Published in Urology (Ridgewood, N.J.) (2014)“…Objective To evaluate microsurgical testicular sperm extraction (micro-TESE) and intracytoplasmic sperm injection (ICSI) treatment in patients with non-mosaic…”
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Oxidative stress‐related miRNAs in spermatozoa may reveal the severity of damage in grade III varicocele
Published in Andrologia (01-10-2020)“…Varicocele is associated with excessive production of reactive oxygen species (ROS). Although the harmful effects of ROS on sperm DNA, proteins and lipids are…”
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8
Sperm retrieval rate and reproductive outcome of infertile men with azoospermia factor c deletion
Published in Andrologia (01-09-2018)“…To evaluate the success rate in sperm retrieval (SR) through microdissection testicular sperm extraction (micro‐TESE) in infertile azoospermia factor c…”
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9
Dynamic Expression and Chromatin Incorporation of ACT and CREM Transcription Factors in Testis Tissues of Infertile Men
Published in Cell journal (Yakhteh) (01-12-2021)“…Activator of CREM in the testis (ACT) is a tissue specific transcription factor which activates cAMP responsive element modulator (CREM), a key transcription…”
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10
Observational retrospective study of Intracytoplasmic sperm injection outcomes of 117 infertile men with severe short tail sperm defect
Published in Andrologia (01-06-2021)“…Intracytoplasmic sperm injection (ICSI) is increasingly used to treat male‐factor infertility when sperm parameters are not proper for intrauterine…”
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11
Evaluation of sperm DNA fragmentation and chromatin structure in infertile men with immotile short‐tail sperm defect
Published in Andrologia (01-02-2020)“…Teratozoospermia is characterised by the presence of spermatozoa with abnormal morphology. One of the morphological disorders that lead to male infertility is…”
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12
Spermatogenesis disorder is associated with mutations in the ligand‐binding domain of an androgen receptor
Published in Andrologia (01-11-2019)“…Androgens play a key role in spermatogenesis, and their functions are mediated by the androgen receptor (AR). Some mutations in the AR gene have the potential…”
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13
Bridging the Gap between AZF Microdeletions and Karyotype: Twelve Years' Experience of an Infertility Center
Published in The world journal of men's health (01-07-2023)“…Despite all past efforts, the current guidelines are not explicit enough regarding the indications for performing azoospermia factor (AZF) screening and…”
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14
Evaluation of Predicting Factors Affecting Sperm Retrieval in Patients with Klinefelter Syndrome: A Prospective Study
Published in International journal of fertility & sterility (01-10-2023)“…This study aimed to evaluate the predicting factors affecting sperm retrieval. We prospectively assessed the relationship between sonographic and…”
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15
Epigenetic Dysregulation of BRDT Gene in Testis Tissues of Infertile Men: Case-Control Study
Published in Cell journal (Yakhteh) (01-02-2022)“…Bromodomain testis associated (BRDT), a testis-specific member of the Bromo- and Extra-Terrminal domain (BET) protein family, is involved in spermatogenesis…”
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16
Alpha-Lipoic Acid Ameliorates Sperm DNA Damage and Chromatin Integrity in Men with High DNA Damage: A Triple Blind Randomized Clinical Trial
Published in Cell journal (Yakhteh) (01-10-2022)“…Objective: Evidence suggests the contributory role of oxidative stress (OS) to sperm DNA damage and eventually, male infertility. Antioxidant supplementation…”
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17
Alpha-Lipoic Acid Supplementation for Male Partner of Couples with Recurrent Pregnancy Loss: A Post hoc analysis in Clinical Trial
Published in International journal of fertility & sterility (01-01-2023)“…Increased sperm DNA damage is known as one of the causes of recurrent pregnancy loss (RPL) which can be due to increased levels of oxidative stress. Therefore,…”
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18
Nuclear Factor Kappa-B Protein Levels in Sperm of Obese Men with and without Diabetes; Cellular Approach in Male Infertility
Published in Cell journal (Yakhteh) (01-01-2023)“…Although the role of obesity and diabetes mellitus (DM) in male infertility is well established, little information about the underlying cellular mechanisms in…”
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The Correlation of Gene Expression of Inflammasome Indicators and Impaired Fertility in Rat Model of Spinal Cord Injury: A Time Course Study
Published in Urology journal (01-11-2017)“…Expression assessment of the inflammasome genes in the acute and the chronic phases of Spinal cord injury (SCI) on adult rat testis and examination of…”
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20
Study of trinucleotide expansions and expression of androgen receptor in infertile men with abnormal spermogram referred to Royan institute
Published in Andrologia (01-12-2018)“…Androgen receptor (AR) mediates androgen activities such as the growth of accessory sex organs, and initiation and promotion of spermatogenesis. There are two…”
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