Search Results - "Sadier, Alexa"

The ectodysplasin pathway: from diseases to adaptations by Sadier, Alexa, Viriot, Laurent, Pantalacci, Sophie, Laudet, Vincent

“…Highlights • The Ectodysplasin pathway controls ectodermal appendages in vertebrates. • The core of the pathway contains three main gene products: EDA, EDAR,…”
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A new developmental mechanism for the separation of the mammalian middle ear ossicles from the jaw by Urban, Daniel J., Anthwal, Neal, Luo, Zhe-Xi, Maier, Jennifer A., Sadier, Alexa, Tucker, Abigail S., Sears, Karen E.

“…Multiple mammalian lineages independently evolved a definitive mammalian middle ear (DMME) through breakdown of Meckel's cartilage (MC). However, the cellular…”
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Unraveling the heritage of lost traits by Sadier, Alexa, Sears, Karen E., Womack, Molly

“…We synthesize ontogenetic work spanning the past century that show evolutionarily lost structures are rarely entirely absent from earlier developmental stages…”
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Bat teeth illuminate the diversification of mammalian tooth classes by Sadier, Alexa, Anthwal, Neal, Krause, Andrew L., Dessalles, Renaud, Lake, Michael, Bentolila, Laurent A., Haase, Robert, Nieves, Natalie A., Santana, Sharlene E., Sears, Karen E.

“…Tooth classes are an innovation that has contributed to the evolutionary success of mammals. However, our understanding of the mechanisms by which tooth…”
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Modeling Edar expression reveals the hidden dynamics of tooth signaling center patterning by Sadier, Alexa, Twarogowska, Monika, Steklikova, Klara, Hayden, Luke, Lambert, Anne, Schneider, Pascal, Laudet, Vincent, Hovorakova, Maria, Calvez, Vincent, Pantalacci, Sophie

“…When patterns are set during embryogenesis, it is expected that they are straightly established rather than subsequently modified. The patterning of the three…”
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Morphological Diversification under High Integration in a Hyper Diverse Mammal Clade by Hedrick, Brandon P., Mutumi, Gregory L., Munteanu, V. David, Sadier, Alexa, Davies, Kalina T. J., Rossiter, Stephen J., Sears, Karen E., Dávalos, Liliana M., Dumont, Elizabeth

“…Diversification and adaptive radiations are tied to evolvability, which in turn is linked to morphological integration. Tightly integrated structures typically…”
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Multifactorial processes underlie parallel opsin loss in neotropical bats by Sadier, Alexa, Davies, Kalina Tj, Yohe, Laurel R, Yun, Kun, Donat, Paul, Hedrick, Brandon P, Dumont, Elizabeth R, Dávalos, Liliana M, Rossiter, Stephen J, Sears, Karen E

“…The loss of previously adaptive traits is typically linked to relaxation in selection, yet the molecular steps leading to such repeated losses are rarely…”
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Insights into the formation and diversification of a novel chiropteran wing membrane from embryonic development by Anthwal, Neal, Urban, Daniel J, Sadier, Alexa, Takenaka, Risa, Spiro, Simon, Simmons, Nancy, Behringer, Richard R, Cretekos, Chris J, Rasweiler, 4th, John J, Sears, Karen E

“…Through the evolution of novel wing structures, bats (Order Chiroptera) became the only mammalian group to achieve powered flight. This achievement preceded…”
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Making a bat: The developmental basis of bat evolution by Sadier, Alexa, Urban, Daniel J, Anthwal, Neal, Howenstine, Aidan O, Sinha, Ishani, Sears, Karen E

“…Bats are incredibly diverse, both morphologically and taxonomically. Bats are the only mammalian group to have achieved powered flight, an adaptation that is…”
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Conserved Features and Evolutionary Shifts of the EDA Signaling Pathway Involved in Vertebrate Skin Appendage Development by Pantalacci, Sophie, Chaumot, Arnaud, Benoît, Gérard, Sadier, Alexa, Delsuc, Frédéric, Douzery, Emmanuel J. P., Laudet, Vincent

“…It is widely accepted that evolutionary changes in conserved developmental signaling pathways play an important role in morphological evolution. However, few…”
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Developmental origins and evolution of bats by Sears, Karen, Sadier, Alexa, Urban, Daniel

“…Through the evolution of novel wing structures, bats (Order Chiroptera) became the only mammalian group to achieve powered flight. This achievement proceeded…”
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The Role of Core and Variable Gene Regulatory Network Modules in Tooth Development and Evolution by Sadier, Alexa, Santana, Sharlene E, Sears, Karen E

“…Synopsis Among the developmental processes that have been proposed to influence the direction of evolution, the modular organization of developmental gene…”
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The Vertebrate Tooth Row: Is It Initiated by a Single Organizing Tooth? by Sadier, Alexa, Jackman, William R., Laudet, Vincent, Gibert, Yann

“…Teeth are one of the most fascinating innovations of vertebrates. Their diversity of shape, size, location, and number in vertebrates is astonishing. If the…”
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Non-model systems in mammalian forelimb evo-devo by Howenstine, Aidan O, Sadier, Alexa, Anthwal, Neal, Lau, Clive LF, Sears, Karen E

“…Mammal forelimbs are highly diverse, ranging from the elongated wing of a bat to the stout limb of the mole. The mammal forelimb has been a long-standing…”
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Bat Dentitions: A Model System for Studies at The Interface of Development, Biomechanics, and Evolution by Santana, Sharlene E, Grossnickle, David M, Sadier, Alexa, Patterson, Edward, Sears, Karen E

“…The evolution of complex dentitions was a major innovation in mammals that facilitated the expansion into new dietary niches that imposed selection for tight…”
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Embryonic evidence uncovers convergent origins of laryngeal echolocation in bats by Nojiri, Taro, Wilson, Laura A.B., López-Aguirre, Camilo, Tu, Vuong Tan, Kuratani, Shigeru, Ito, Kai, Higashiyama, Hiroki, Son, Nguyen Truong, Fukui, Dai, Sadier, Alexa, Sears, Karen E., Endo, Hideki, Kamihori, Satoshi, Koyabu, Daisuke

“…Bats are the second-most speciose group of mammals, comprising 20% of species diversity today. Their global explosion, representing one of the greatest…”
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Find the food first: An omnivorous sensory morphotype predates biomechanical specialization for plant based diets in phyllostomid bats by Hall, Ronald P., Mutumi, Gregory L., Hedrick, Brandon P., Yohe, Laurel R., Sadier, Alexa, Davies, Kalina T. J., Rossiter, Stephen J., Sears, Karen, Dávalos, Liliana M., Dumont, Elizabeth R.

“…The role of mechanical morphologies in the exploitation of novel niche space is well characterized; however, the role of sensory structures in unlocking new…”
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The hierarchical radiation of phyllostomid bats as revealed by adaptive molar morphology by Grossnickle, David M, Sadier, Alexa, Patterson, Edward, Cortés-Viruet, Nashaly N, Jiménez-Rivera, Stephanie M, Sears, Karen E, Santana, Sharlene E

“…Adaptive radiations are bursts in biodiversity that generate new evolutionary lineages and phenotypes. However, because they typically occur over millions of…”
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Disentangling Mechanical and Sensory Modules in the Radiation of Noctilionoid Bats by Mutumi, Gregory L, Hall, Ronald P, Hedrick, Brandon P, Yohe, Laurel R, Sadier, Alexa, Davies, Kalina T J, Rossiter, Stephen J, Sears, Karen E, Dávalos, Liliana M, Dumont, Elizabeth R

“…AbstractWith diverse mechanical and sensory functions, the vertebrate cranium is a complex anatomical structure whose shifts between modularity and…”
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Grand Challenges in Comparative Tooth Biology by Hulsey, C Darrin, Cohen, Karly E, Johanson, Zerina, Karagic, Nidal, Meyer, Axel, Miller, Craig T, Sadier, Alexa, Summers, Adam P, Fraser, Gareth J

“…Abstract Teeth are a model system for integrating developmental genomics, functional morphology, and evolution. We are at the cusp of being able to address…”
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