Search Results - "Sadato, Daichi"
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Impact of genetic alterations on central nervous system progression of primary vitreoretinal lymphoma
Published in Haematologica (Roma) (06-06-2024)“…Primary vitreoretinal lymphoma (PVRL) is a rare malignant lymphoma subtype with an unfavorable prognosis due to frequent central nervous system (CNS)…”
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2
Prognostic impact of TP53 mutation, monosomal karyotype, and prior myeloid disorder in nonremission acute myeloid leukemia at allo-HSCT
Published in Bone marrow transplantation (Basingstoke) (01-02-2021)“…Outcomes after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in nonremission acute myeloid leukemia (AML) are dismal [2-year overall survival…”
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3
Data-driven score tuning for ChooseLD: A structure-based drug design algorithm with empirical scoring and evaluation of ligand–protein docking predictability
Published in Biophysics and Physicobiology (2024)“…Computerized molecular docking methodologies are pivotal in in-silico screening, a crucial facet of modern drug design. ChooseLD, a docking simulation…”
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4
Mitochondrial Fragmentation Triggers Ineffective Hematopoiesis in Myelodysplastic Syndromes
Published in Cancer discovery (01-01-2022)“…Ineffective hematopoiesis is a fundamental process leading to the pathogenesis of myelodysplastic syndromes (MDS). However, the pathobiological mediators of…”
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5
Gene rearrangements of MLL and RUNX1 sporadically occur in normal CD34+ cells under cytokine stimulation
Published in Cancer science (01-05-2020)“…Gene rearrangements of MLL/KMT2A or RUNX1 are the major cause of therapy‐related leukemia. Moreover, MLL rearrangements are the major cause of infant leukemia,…”
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Successful treatment of two cases with Philadelphia-chromosome positive acute lymphoblastic leukemia who relapsed after allogeneic stem cell transplantation and the treatments with novel immunotherapies and ponatinib
Published in Hematology (Luxembourg) (01-12-2024)“…The outcomes of relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) resistant to new drugs such as tyrosine kinase inhibitors,…”
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Archival bone marrow smears are useful in targeted next-generation sequencing for diagnosing myeloid neoplasms
Published in PloS one (23-07-2021)“…Gene abnormalities, including mutations and fusions, are important determinants in the molecular diagnosis of myeloid neoplasms. The use of bone marrow (BM)…”
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8
Attenuated humoral response against SARS‐CoV‐2 mRNA vaccination in allogeneic stem cell transplantation recipients
Published in Cancer science (01-02-2023)“…Antibody persistence several months after severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) mRNA vaccination in allogeneic stem cell transplantation…”
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9
Impact of gene alterations on clinical outcome in young adults with myelodysplastic syndromes
Published in Scientific reports (14-02-2023)“…Young adults with myelodysplastic syndrome (MDS) are rare, and the clinical significance of driver mutations has not yet been analysed. We analysed the gene…”
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10
Labile CD22 and CD19 expression in a case of Philadelphia chromosome-like acute lymphoblastic leukemia
Published in Leukemia & lymphoma (10-11-2022)Get full text
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11
Development of a simple and quick immunochromatography method for detection of anti-HPV-16/-18 antibodies
Published in PloS one (03-02-2017)“…Immunochromatography (IC) is widely used to detect target molecules in biological fluids. Since this method can be performed without a special technique or…”
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12
A third dose of COVID‐19 mRNA vaccine induces limited humoral response in stem cell transplant recipients who got two vaccine doses before transplant
Published in EJHaem (01-02-2023)“…According to the manufacturer's instructions, ≥10 arbitrary units (AU)/ml were considered positive. [...]our preliminary data first suggested that a third dose…”
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13
Eukaryotic translation initiation factor 3 (eIF3) subunit e is essential for embryonic development and cell proliferation
Published in FEBS open bio (01-08-2018)“…Mammalian eukaryotic translation initiation factor 3 (eIF3) is the largest complex of the translation initiation factors. The eIF3 complex is comprised of…”
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14
Mutation profiles of diffuse large B‐cell lymphoma transformation of splenic B‐cell lymphoma/leukemia, unclassifiable on whole‐exome sequencing
Published in EJHaem (01-11-2021)“…A 58‐year‐old male was diagnosed with splenic B‐cell lymphoma/leukemia, unclassifiable (SPLL‐U). The lymphoma transformed into diffuse large B‐cell lymphoma…”
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15
Potential prognostic impact of EBV RNA‐seq reads in gastric cancer: a reanalysis of The Cancer Genome Atlas cohort
Published in FEBS open bio (01-03-2020)“…Epstein–Barr virus (EBV)‐associated gastric cancer (EBVaGC), whose prognosis remains controversial, is diagnosed by in situ hybridization of EBV‐derived…”
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16
Donor-derived gene mutations in sex chromosome loss after stem cell transplantation
Published in British journal of haematology (01-11-2021)Get full text
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17
A review of comprehensive genomic profiling testing in a Japanese single institution
Published in Journal of clinical oncology (20-01-2024)“…740 Background: In Japan, comprehensive genomic profiling (CGP) testing, including OncoGuide and FoundationOne CDx (F-1), were approved in June 2019 for…”
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18
RNA–DNA hybrids on protein coding genes are stabilized by loss of RNase H and are associated with DNA damages during S‐phase in fission yeast
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-11-2024)“…RNA–DNA hybrid is a part of the R‐loop which is an important non‐standard nucleic acid structure. RNA–DNA hybrid/R‐loop causes genomic instability by inducing…”
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MO32-6 The development of an expert panel support program using the Python programming language
Published in Annals of oncology (01-11-2023)Get full text
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20
Data-driven score tuning for ChooseLD: A structure-based drug design algorithm with empirical scoring and evaluation of ligand–protein docking predictability
Published in Biophysics and Physicobiology (2024)“…Computerized molecular docking methodologies are pivotal in in-silico screening, a crucial facet of modern drug design. ChooseLD, a docking simulation…”
Get full text
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