Search Results - "Sacks, David B"

Trends in Prevalence and Control of Diabetes in the United States, 1988―1994 and 1999―2010 by SELVIN, Elizabeth, PARRINELLO, Christina M, SACKS, David B, CORESH, Josef

“…Trends in the prevalence and control of diabetes defined by hemoglobin A1c (HbA1c) levels are important for health care policy and planning. To update trends…”
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Role of Glycated Proteins in the Diagnosis and Management of Diabetes: Research Gaps and Future Directions by Welsh, Kerry J, Kirkman, M Sue, Sacks, David B

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Glucose Management Indicator (GMI): A New Term for Estimating A1C From Continuous Glucose Monitoring by Bergenstal, Richard M, Beck, Roy W, Close, Kelly L, Grunberger, George, Sacks, David B, Kowalski, Aaron, Brown, Adam S, Heinemann, Lutz, Aleppo, Grazia, Ryan, Donna B, Riddlesworth, Tonya D, Cefalu, William T

“…While A1C is well established as an important risk marker for diabetes complications, with the increasing use of continuous glucose monitoring (CGM) to help…”
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Status of hemoglobin A1c measurement and goals for improvement: from chaos to order for improving diabetes care by Little, Randie R, Rohlfing, Curt L, Sacks, David B

“…The Diabetes Control and Complications Trial (DCCT) and United Kingdom Prospective Diabetes Study (UKPDS) established the importance of hemoglobin A(1c) (Hb…”
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The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling by Thines, Louise, Roushar, Francis J, Hedman, Andrew C, Sacks, David B

“…The scaffold protein IQGAP1 assembles multiprotein signaling complexes to influence biological functions. Cell surface receptors, particularly receptor…”
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Establishment of Community-Based Reference Intervals for Fructosamine, Glycated Albumin, and 1,5-Anhydroglucitol by Selvin, Elizabeth, Warren, Bethany, He, Xintong, Sacks, David B, Saenger, Amy K

“…There is growing interest in fructosamine, glycated albumin, and 1,5-anhydroglucitol (1,5-AG) as alternative measures of hyperglycemia, particularly for use in…”
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Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus by Sacks, David B, Arnold, Mark, Bakris, George L, Bruns, David E, Horvath, Andrea Rita, Kirkman, M. Sue, Lernmark, Ake, Metzger, Boyd E, Nathan, David M

“…BACKGROUND: Multiple laboratory tests are used to diagnose and manage patients with diabetes mellitus. The quality of the scientific evidence supporting the…”
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Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus by Sacks, David B, Arnold, Mark, Bakris, George L, Bruns, David E, Horvath, Andrea Rita, Kirkman, M Sue, Lernmark, Ake, Metzger, Boyd E, Nathan, David M

“…Multiple laboratory tests are used to diagnose and manage patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these…”
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IQGAPs in cancer: A family of scaffold proteins underlying tumorigenesis by White, Colin D., Brown, Matthew D., Sacks, David B.

“…The IQGAP family comprises three proteins in humans. The best characterized is IQGAP1, which participates in protein–protein interactions and integrates…”
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Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex by Sharma, Sonia, Findlay, Gregory M, Bandukwala, Hozefa S, Oberdoerffer, Shalini, Baust, Beate, Li, Zhigang, Schmidt, Valentina, Hogan, Patrick G, Sacks, David B, Rao, Anjana

“…Nuclear factor of activated T cells (NFAT) proteins are Ca²⁺-regulated transcription factors that control gene expression in many cell types. NFAT proteins…”
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Controversies Around the Measurement of Blood Ketones to Diagnose and Manage Diabetic Ketoacidosis by Kilpatrick, Eric S, Butler, Alexandra E, Ostlundh, Linda, Atkin, Stephen L, Sacks, David B

“…The measurement of blood ketones in preference to urine ketones has become a well-established tool in the diagnosis and management of diabetic ketoacidosis…”
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Critical Roles of Clinical Laboratorians in Translational Research and Applied Sciences—Experts’ Insights and Experiences by Farnsworth, Moderators: Christopher, Zhao, Zhen, Apple, Experts: Fred, Collinson, Paul, DeMarco, Mari L, Gronowski, Ann, B. Sacks, David, Zhu, Yusheng

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IQGAP1 in cellular signaling: bridging the GAP by Brown, Matthew D., Sacks, David B.

“…IQGAP1 was identified in 1994 as a widely expressed IQ domain-containing protein with a region containing sequence similarity to the Ras GTPase-activating…”
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A New Look at Screening and Diagnosing Diabetes Mellitus by Saudek, Christopher D., Herman, William H., Sacks, David B., Bergenstal, Richard M., Edelman, David, Davidson, Mayer B.

“…Objective: Diabetes is underdiagnosed. About one third of people with diabetes do not know they have it, and the average lag between onset and diagnosis is 7…”
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IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity by Sayedyahossein, Samar, Li, Zhigang, Hedman, Andrew C., Morgan, Chase J., Sacks, David B.

“…During development, the Hippo signaling pathway regulates key physiological processes, such as control of organ size, regeneration, and stem cell biology…”
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IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration by Choi, Suyong, Thapa, Narendra, Hedman, Andrew C, Li, Zhigang, Sacks, David B, Anderson, Richard A

“…Phosphatidylinositol 4,5 bisphosphate (PIP 2 ) is a key lipid messenger for regulation of cell migration. PIP 2 modulates many effectors, but the specificity…”
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Tight glucose control in the intensive care unit: are glucose meters up to the task? by Scott, Mitchell G, Bruns, David E, Boyd, James C, Sacks, David B

“…Typical TGC protocols consist of placing postoperative and critically ill patients on a continuous intravenous insulin infusion, checking their blood glucose…”
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Discovery of small molecule inhibitors that effectively disrupt IQGAP1-Cdc42 interaction in breast cancer cells by Sayedyahossein, Samar, Smith, Jessica, Barnaeva, Elena, Li, Zhigang, Choe, Jun, Ronzetti, Michael, Dextras, Christopher, Hu, Xin, Marugan, Juan, Southall, Noel, Baljinnyam, Bolormaa, Thines, Louise, Tran, Andy D., Ferrer, Marc, Sacks, David B.

“…The small GTPase Cdc42 is an integral component of the cytoskeleton, and its dysregulation leads to pathophysiological conditions, such as cancer. Binding of…”
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IQGAP1 Is a Scaffold for Mitogen-Activated Protein Kinase Signaling by Roy, Monideepa, Li, Zhigang, Sacks, David B.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Structural Basis for Cdc42-Induced Dimerization of IQGAPs by LeCour, Louis, Boyapati, Vamsi. K., Liu, Jing, Li, Zhigang, Sacks, David B., Worthylake, David K.

“…In signaling, Rho-family GTPases bind effector proteins and alter their behavior. Here we present the crystal structure of Cdc42·GTP bound to the…”
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