Search Results - "Sachse, F.B."

Models of cardiac tissue electrophysiology: Progress, challenges and open questions by Clayton, R.H., Bernus, O., Cherry, E.M., Dierckx, H., Fenton, F.H., Mirabella, L., Panfilov, A.V., Sachse, F.B., Seemann, G., Zhang, H.

“…Models of cardiac tissue electrophysiology are an important component of the Cardiac Physiome Project, which is an international effort to build biophysically…”
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Mechanical Modulation of the Transverse Tubular System in Cardiomyocytes: Its Potential Role in Remodelling in Heart Disease by Sachse, F.B, Harrison, Nora Eccles

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Towards Modeling of Cardiac Micro-Structure With Catheter-Based Confocal Microscopy: A Novel Approach for Dye Delivery and Tissue Characterization by Lasher, R.A., Hitchcock, R.W., Sachse, F.B.

“…This work presents a methodology for modeling of cardiac tissue micro-structure. The approach is based on catheter-based confocal imaging systems, which are…”
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A Modified Local Control Model for Ca Transients in Cardiomyocytes: Junctional Flux is Accompanied by Release from Non-junctional RyRs by Bridge, J.H.B, Torres, N, Spitzer, K.W, Izu, L, Goldhaber, J.I, Sachse, F.B

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Remodeling of the transverse tubular system after myocardial infarction in rabbit correlates with local fibrosis: A potential role of biomechanics by Seidel, T., Sankarankutty, A.C., Sachse, F.B.

“…The transverse tubular system (t-system) of ventricular cardiomyocytes is essential for efficient excitation-contraction coupling. In cardiac diseases, such as…”
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Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): Standardised reporting for model reproducibility, interoperability, and data sharing by Quinn, T.A., Granite, S., Allessie, M.A., Antzelevitch, C., Bollensdorff, C., Bub, G., Burton, R.A.B., Cerbai, E., Chen, P.S., Delmar, M., DiFrancesco, D., Earm, Y.E., Efimov, I.R., Egger, M., Entcheva, E., Fink, M., Fischmeister, R., Franz, M.R., Garny, A., Giles, W.R., Hannes, T., Harding, S.E., Hunter, P.J., Iribe, G., Jalife, J., Johnson, C.R., Kass, R.S., Kodama, I., Koren, G., Lord, P., Markhasin, V.S., Matsuoka, S., McCulloch, A.D., Mirams, G.R., Morley, G.E., Nattel, S., Noble, D., Olesen, S.P., Panfilov, A.V., Trayanova, N.A., Ravens, U., Richard, S., Rosenbaum, D.S., Rudy, Y., Sachs, F., Sachse, F.B., Saint, D.A., Schotten, U., Solovyova, O., Taggart, P., Tung, L., Varró, A., Volders, P.G., Wang, K., Weiss, J.N., Wettwer, E., White, E., Wilders, R., Winslow, R.L., Kohl, P.

“…Cardiac experimental electrophysiology is in need of a well-defined Minimum Information Standard for recording, annotating, and reporting experimental data. As…”
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Experimental and computational studies of strain–conduction velocity relationships in cardiac tissue by McNary, T.G., Sohn, K., Taccardi, B., Sachse, F.B.

“…Velocity of electrical conduction in cardiac tissue is a function of mechanical strain. Although strain-modulated velocity is a well established finding in…”
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Comparison of measured and simulated deformation of a left ventricle by Mohr, M.B., Seemann, G., Sachse, F.B., Jung, B., Dössel, O.

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Development of a human body model for numerical calculation of electrical fields by Sachse, F.B, Werner, C.D, Meyer-Waarden, K, Dössel, O

“…Knowledge of the distribution of electrical fields in the human body is of importance for scientists, engineers and physicians. This paper shows one way to…”
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Visualization of electrical current flow with a new streamline technique: application in mono- and bidomain simulations of cardiac tissue by Sachse, F.B., Taccardi, B.

“…Mathematical modeling and computer-based simulation of electrical fields in the heart provide important insights into the cardiac electrophysiological…”
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Modeling force development in the sarcomere in consideration of electromechanical coupling by Glänzel, K, Sachse, F B, Seemann, G, Riedel, C, Dössel, O

“…Models of the cellular force development simulate the contractive behavior of the sarcomere. In conjunction with electrophysiological models they can…”
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Modeling of force development in the human heart with a cellular automaton parameterized by numerical simulations by Sachse, F.B., Seemann, G., Werner, C.D.

“…Models of the human heart are introduced which describe the anatomy, electrical excitation propagation and force development. The anatomical models were…”
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Incorporating blood pressure load into an elastomechanical ventricular mod by Mohr, M.B., Schnell, R.R., Seemann, G., Sachse, F.B., Dossel, O.

“…Elastomechanical modeling constitutes an essential step for realistic computer simulations of the cardiac system. The deformation of tissue effects e.g…”
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Modeling of heterogeneous electrophysiology in the human heart with respect to ECG genesis by Weiss, D.L., Seemann, G., Keller, D.U.J., Farina, D., Sachse, F.B., Dossel, O.

“…Heterogeneity of ion channel properties within human ventricular tissue determines the sequence of repolarization under healthy conditions. In this…”
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A Software Framework for Solving Bioelectrical Field Problems Based on Finite Elements by Sachse, F.B., Cole, M.J., Stinstra, J.G.

“…Computational modeling and simulation can provide important insights into the electrical and electrophysiological properties of cells, tissues, and organs…”
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A Framework for Modeling of Mechano-Electrical Feedback Mechanisms of Cardiac Myocytes and Tissues by Sachse, F.B., Hunter, G.A.M., Weiss, D.L., Seemann, G.

“…The term cardiac mechano- electrical feedback precis the various phenomena related to modulation of electrophysiology by mechanical deformation of cells and…”
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Sensitivity Analysis of Cardiac Electrophysiological Models Using Polynomial Chaos by Geneser, S.E., Kirby, R.M., Sachse, F.B.

“…Mathematical models of biophysical phenomena have proven useful in the reconstruction of experimental data and prediction of biological behavior. By…”
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Conduction Velocity in Myocardium Modulated by Strain: Measurement Instrumentation and Initial Results by Sachse, F.B., Steadman, B.W., Bridge, J.H.B., Punske, B.B., Taccardi, B.

“…Quantification of the relationship between strain and excitation velocity in cardiac muscle gives important insights into the significance and contribution of…”
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A software framework for solving problems of bioelectricity applying high-order finite elements by Cole, M., Sachse, F.B., Weinstein, D.M., Parker, S., Kirby, R.M.

“…Electrical activity in biological media can be described in a mathematical way, which is applicable to computer-based simulation. Biophysically mathematical…”
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Activity of self-depolarizing pacemaker cells bio-engineered in virtual heterogeneous ventricular tissue by Weiss, D.L., Seemann, G., Sachse, F.B., Doessel, O.

“…Genetically engineered cardiac pacemakers are a proposed alternative or support to the state-of-the-art electronic devices. Down-regulation of the expression…”
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