Search Results - "Sachs, F."
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Evaluation of Unreliable Flow Lines with Limited Buffer Capacities and Spare Part Provisioning
Published in European journal of operational research (16-10-2022)“…•A flow line model with failures due to stockable, critical components is presented.•Important performance measures for short lines are calculated by a Markov…”
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Spare parts or buffer? How to design a transfer line with unreliable machines
Published in European journal of operational research (01-07-2020)“…•A transfer lines with two machines and one buffer where failures are due to critical components which can be hold in stock is presented.•An optimal system…”
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The Kinetics and the Permeation Properties of Piezo Channels
Published in Current topics in membranes (2017)“…Piezo channels are eukaryotic, cation-selective mechanosensitive channels (MSCs), which show rapid activation and voltage-dependent inactivation. The kinetics…”
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Infant behavioral reactivity predicts change in amygdala volume 12 years later
Published in Developmental cognitive neuroscience (01-04-2020)“…The current study examined the link between temperamental reactivity in infancy and amygdala development in middle childhood. A sample (n = 291) of…”
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Tarantula peptide inhibits atrial fibrillation
Published in Nature (London) (04-01-2001)“…A peptide from spider venom can prevent the heartbeat from losing its rhythm…”
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Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events
Published in Biophysical journal (1996)“…We present here a maximal likelihood algorithm for estimating single-channel kinetic parameters from idealized patch-clamp data. The algorithm takes into…”
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7
Mechanoelectric feedback in cardiac cells
Published in Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences (15-06-2001)“…Cardiac electrophysiology is affected by cardiac mechanics. The input from the heart's mechanical environment to its electrical behaviour has been termed…”
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Triostin A derived hybrid for simultaneous DNA binding and metal coordination
Published in Amino acids (01-07-2011)“…The natural product triostin A is known as an antibiotic based on specific DNA recognition. Structurally, a bicyclic depsipeptide backbone provides a…”
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Thermodynamics of mechanosensitivity
Published in Physical biology (01-06-2004)“…Mechanosensitivity of ion channels is conventionally interpreted as being driven by a change of their in-plane cross-sectional area A(msc). This, however, does…”
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Mechanosensitive ion channels in nonspecialized cells
Published in Reviews of physiology, biochemistry and pharmacology (01-01-1998)Get more information
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Voltage-induced membrane movement
Published in Nature (London) (27-09-2001)“…Thermodynamics predicts that transmembrane voltage modulates membrane tension and that this will cause movement. The magnitude and polarity of movement is…”
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Energetic and spatial parameters for gating of the bacterial large conductance mechanosensitive channel, MscL
Published in The Journal of general physiology (01-04-1999)“…MscL is multimeric protein that forms a large conductance mechanosensitive channel in the inner membrane of Escherichia coli. Since MscL is gated by tension…”
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13
Maximum likelihood estimation of aggregated Markov processes
Published in Proceedings of the Royal Society. B, Biological sciences (22-03-1997)“…We present a maximum likelihood method for the modelling of aggregated Markov processes. The method utilizes the joint probability density of the observed…”
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14
Cortical Thickness and Subcortical Gray Matter Volume in Pediatric Anxiety Disorders
Published in Neuropsychopharmacology (New York, N.Y.) (01-11-2017)“…Perturbations in the prefrontal cortex (PFC), hippocampus, and amygdala are implicated in the development of anxiety disorders. However, most structural…”
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Anticipatory Threat Responding: Associations With Anxiety, Development, and Brain Structure
Published in Biological psychiatry (1969) (15-05-2020)“…While translational theories link neurodevelopmental changes in threat learning to pathological anxiety, findings from studies in patients inconsistently…”
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Mechanical transduction by membrane ion channels : a mini review
Published in Molecular and cellular biochemistry (01-01-1991)“…There are ion channels in the cell membrane that are sensitive to stress in the membrane cytoskeleton. Some channels turn on with stress, others turn off. In…”
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Triostin A Derived Cyclopeptide as Architectural Template for the Alignment of Four Recognition Units
Published in ChemistryOpen (Weinheim) (01-08-2014)“…The DNA bisintercalator triostin A is structurally based on a disulfide‐bridged depsipeptide scaffold that provides preorganization of two quinoxaline units in…”
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Calcium imaging of mechanically induced fluxes in tissue-cultured chick heart: role of stretch-activated ion channels
Published in The American journal of physiology (01-04-1992)“…Heart rate and contractility are sensitive to stretch. To better understand the origin of these effects, we have studied the effect of mechanical stimuli on a…”
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Developmental pathways to social anxiety and irritability: The role of the ERN
Published in Development and psychopathology (01-08-2020)“…Early behaviors that differentiate later biomarkers for psychopathology can guide preventive efforts while also facilitating pathophysiological research. We…”
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Building a Program of Expanded Peer Support for the Entire Health Care Team: No One Left Behind
Published in Joint Commission journal on quality and patient safety (01-12-2021)“…Medical errors can cause second victim syndrome (SVS) in caregivers. Literature describing the development of effective peer support programs is limited. This…”
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