Search Results - "Sachiko, Ogasawara"

Antiproliferative Effect of Lenvatinib on Human Liver Cancer Cell Lines In Vitro and In Vivo by Ogasawara, Sachiko, Mihara, Yutaro, Kondo, Reiichiro, Kusano, Hironori, Akiba, Jun, Yano, Hirohisa

“…Background/Aim: Lenvatinib is a potent inhibitor of receptor tyrosine kinases, targeting vascular endothelial growth factor receptors (VEGFR1-3), fibroblast…”
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Knockout of high-mobility group box 1 in B16F10 melanoma cells induced host immunity-mediated suppression of in vivo tumor growth by Yokomizo, Kanako, Waki, Kayoko, Ozawa, Miyako, Yamamoto, Keiko, Ogasawara, Sachiko, Yano, Hirohisa, Yamada, Akira

“…High-mobility group box 1 (HMGB1) has been reported as a damage-associated molecular pattern (DAMP) molecule that is released from damaged or dead cells and…”
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Mild Glucose Starvation Induces KDM2A-Mediated H3K36me2 Demethylation through AMPK To Reduce rRNA Transcription and Cell Proliferation by Tanaka, Yuji, Yano, Hirohisa, Ogasawara, Sachiko, Yoshioka, Sho-ichi, Imamura, Hiromi, Okamoto, Kengo, Tsuneoka, Makoto

“…Environmental conditions control rRNA transcription. Previously, we found that serum and glucose deprivation induces KDM2A-mediated H3K36me2 demethylation in…”
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Aldehyde dehydrogenase 1 identifies cells with cancer stem cell-like properties in a human renal cell carcinoma cell line by Ueda, Kosuke, Ogasawara, Sachiko, Akiba, Jun, Nakayama, Masamichi, Todoroki, Keita, Ueda, Keiko, Sanada, Sakiko, Suekane, Shigetaka, Noguchi, Masanori, Matsuoka, Kei, Yano, Hirohisa

“…Cancer stem cells (CSC) or cancer stem cell-like cells (CSC-LCs) have been identified in many malignant tumors. CSCs are proposed to be related with drug…”
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Distinctive clinicopathological features and KRAS and IDH1/2 mutation status of cholangiolocellular carcinoma by Kusano, Hironori, Naito, Yoshiki, Mihara, Yutaro, Kondo, Reiichiro, Ogasawara, Sachiko, Akiba, Jun, Nakashima, Osamu, Yano, Hirohisa

“…Aim Cholangiolocellular carcinoma (CLC) is classified as a subtype of combined hepatocellular cholangiocarcinoma with stem‐cell features (CHC‐SC) in the latest…”
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Androgen receptor expression is useful to predict the therapeutic effect in HER2-positive breast carcinoma by Akashi, Momoko, Yamaguchi, Rin, Kusano, Hironori, Ogasawara, Sachiko, Abe, Eiji, Obara, Hitoshi, Yamaguchi, Miki, Akiba, Jun, Kakuma, Tatsuyuki, Tanaka, Maki, Akagi, Yoshito, Yano, Hirohisa

“…Purpose Although HER2-positive (HER2+) invasive breast carcinomas (BC) have a different clinical therapeutic responsiveness according to estrogen and…”
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Soluble Immune Checkpoint Molecules as Predictors of Efficacy in Immuno-Oncology Combination Therapy in Advanced Renal Cell Carcinoma by Ueda, Kosuke, Uemura, Keiichiro, Ito, Naoki, Sakai, Yuya, Ohnishi, Satoshi, Suekane, Hiroki, Kurose, Hirofumi, Hiroshige, Tasuku, Chikui, Katsuaki, Nishihara, Kiyoaki, Nakiri, Makoto, Suekane, Shigetaka, Ogasawara, Sachiko, Yano, Hirohisa, Igawa, Tsukasa

“…Immuno-oncology (IO) combination therapy is the first-line treatment for advanced renal cell carcinoma (RCC). However, biomarkers for predicting the response…”
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Prediction Model with HLA-A33:03 Reveals Number of Days to Develop Liver Cancer from Blood Test by Nishida, Nao, Ohashi, Jun, Suda, Goki, Chiyoda, Takehiro, Tamaki, Nobuharu, Tomiyama, Takahiro, Ogasawara, Sachiko, Sugiyama, Masaya, Kawai, Yosuke, Khor, Seik-Soon, Nagasaki, Masao, Fujimoto, Akihiro, Tsuchiura, Takayo, Ishikawa, Miyuki, Matsuda, Koichi, Yano, Hirohisa, Yoshizumi, Tomoharu, Izumi, Namiki, Hasegawa, Kiyoshi, Sakamoto, Naoya, Mizokami, Masashi, Tokunaga, Katsushi

“…The development of liver cancer in patients with hepatitis B is a major problem, and several models have been reported to predict the development of liver…”
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Malic enzyme 1 is a potential marker of combined hepatocellular cholangiocarcinoma, subtype with stem‐cell features, intermediate‐cell type by Mihara, Yutaro, Akiba, Jun, Ogasawara, Sachiko, Kondo, Reiichiro, Fukushima, Hiroto, Itadani, Hiraku, Obara, Hitoshi, Kakuma, Tatsuyuki, Kusano, Hironori, Naito, Yoshiki, Okuda, Koji, Nakashima, Osamu, Yano, Hirohisa

“…Aim Combined hepatocellular cholangiocarcinoma, subtype with stem‐cell features, intermediate‐cell subtype (INT) shows various histological appearances and…”
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KDM2A-dependent reduction of rRNA transcription on glucose starvation requires HP1 in cells, including triple-negative breast cancer cells by Okamoto, Kengo, Tanaka, Yuji, Ogasawara, Sachiko, Obuse, Chikashi, Nakayama, Jun-Ichi, Yano, Hirohisa, Tsuneoka, Makoto

“…Triple-negative breast cancer (TNBC) is very aggressive and lacks specific therapeutic targets. Ribosome RNAs (rRNAs) are central components of ribosomes and…”
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Epithelial cell adhesion molecule-positive human hepatic neoplastic cells: development of combined hepatocellular-cholangiocarcinoma in mice by Ogasawara, Sachiko, Akiba, Jun, Nakayama, Masamichi, Nakashima, Osamu, Torimura, Takuji, Yano, Hirohisa

“…Background and Aim Human combined hepatocellular‐cholangiocarcinoma (CHC) expresses several hepatic stem/progenitor cell (HSPC) markers, suggesting this…”
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SUOX is negatively associated with multistep carcinogenesis and proliferation in oral squamous cell carcinoma by Nakamura, Ken, Akiba, Jun, Ogasawara, Sachiko, Naito, Yoshiki, Nakayama, Masamichi, Abe, Yushi, Kusukawa, Jingo, Yano, Hirohisa

“…Oral squamous cell carcinoma (OSCC) is the most common malignant tumor in the head and neck region. The aim of this study was to identify the key molecules and…”
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Des-γ-carboxyprothrombin (DCP) and NX-DCP expressions and their relationship with clinicopathological features in hepatocellular carcinoma by Sumi, Akiko, Akiba, Jun, Ogasawara, Sachiko, Nakayama, Masamichi, Nomura, Yoriko, Yasumoto, Makiko, Sanada, Sakiko, Nakashima, Osamu, Abe, Toshi, Yano, Hirohisa

“…Des-γ-carboxyprothrombin (DCP) has been used as a tumor marker for hepatocellular carcinoma (HCC). Recently the DCP/NX-DCP ratio, calculated by dividing DCP by…”
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Accelerated expression of a Myc target gene Mina53 in aggressive hepatocellular carcinoma by Ogasawara, Sachiko, Komuta, Mina, Nakashima, Osamu, Akiba, Jun, Tsuneoka, Makoto, Yano, Hirohisa

“…Aim:  Expressions of the myc target genes Mina53 and mimitin are high in esophageal squamous cell carcinoma and colon cancer, and their relationship to cell…”
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Pegylated interferon-α2a inhibits proliferation of human liver cancer cells in vitro and in vivo by Kusano, Hironori, Akiba, Jun, Ogasawara, Sachiko, Sanada, Sakiko, Yasumoto, Makiko, Nakayama, Masamichi, Ueda, Keiko, Ueda, Kosuke, Kurita, Takashi, Todoroki, Keita, Umeno, Yumi, Nakashima, Osamu, Yano, Hirohisa

“…We investigated the effects of pegylated interferon-α2a (PEG-IFN-α2a) on the growth of human liver cancer cells. The effect of PEG-IFN-α2a on the proliferation…”
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Programmed death-ligand 1 expression is an unfavorable prognostic factor of hepatocellular carcinoma after archiving sustained virologic response for hepatitis C virus infection by Kondo, Reiichiro, Akiba, Jun, Ogasawara, Sachiko, Nakashima, Osamu, Naito, Yoshiki, Kusano, Hironori, Mihara, Yutaro, Tanigawa, Masahiko, Yano, Hirohisa

“…The aim of the present study was to study the pathological prognostic factor of initial hepatocellular carcinoma (HCC) after archiving sustained virologic…”
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High sulfite oxidase expression could predict postoperative biochemical recurrence in patients with prostate cancer by Kurose, Hirofumi, Naito, Yoshiki, Akiba, Jun, Kondo, Reiichiro, Ogasawara, Sachiko, Kusano, Hironori, Sanada, Sakiko, Abe, Hideyuki, Kakuma, Tatsuyuki, Ueda, Kosuke, Igawa, Tsukasa, Yano, Hirohisa

“…Sulfite oxidase (SUOX) is a metalloenzyme that plays a role in ATP synthesis via oxidative phosphorylation in mitochondria and has been reported to also be…”
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RECQL1 DNA repair helicase: a potential therapeutic target and a proliferative marker against ovarian cancer by Sanada, Sakiko, Futami, Kazunobu, Terada, Atsumu, Yonemoto, Koji, Ogasawara, Sachiko, Akiba, Jun, Yasumoto, Makiko, Sumi, Akiko, Ushijima, Kimio, Kamura, Toshiharu, Furuichi, Yasuhiro, Yano, Hirohisa

“…This study analyzed the clinicopathological correlation between ovarian cancer (OC) and RECQL1 DNA helicase to assess its therapeutic potential. Surgically…”
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Antiproliferative effects of sorafenib and pegylated IFN-α2b on human liver cancer cells in vitro and in vivo by KUSANO, HIRONORI, OGASAWARA, SACHIKO, AKIBA, JUN, NAKAYAMA, MASAMICHI, UEDA, KOSUKE, YANO, HIROHISA

“…Novel therapeutic strategies are needed to treat patients with advanced hepatocellular carcinoma (HCC). Combination therapy of sorafenib and type I interferon…”
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Expression of vascular endothelial growth factor in human hepatocellular carcinoma by Yamaguchi, Rin, Yano, Hirohisa, Iemura, Akihiro, Ogasawara, Sachiko, Haramaki, Makoto, Kojiro, Masamichi

“…Vascular endothelial growth factor (VEGF) is thought to take an important role in tumor angiogenesis. The present study examined VEGF expression…”
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