Search Results - "Sachdev, Shaurya"

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  1. 1

    Molecular Processes Leading to “Necking” in Extensional Flow of Polymer Solutions: Using Microfluidics and Single DNA Imaging by Sachdev, Shaurya, Muralidharan, Aswin, Boukany, Pouyan E

    Published in Macromolecules (27-12-2016)
    “…We study the necking and pinch-off dynamics of liquid droplets that contain a semidilute polymer solution of polyacrylamide close to overlap concentration by…”
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    Journal Article
  2. 2

    Efficient Gene Transfection by Electroporation—In Vitro and In Silico Study of Pulse Parameters by Potočnik, Tjaša, Sachdev, Shaurya, Polajžer, Tamara, Maček Lebar, Alenka, Miklavčič, Damijan

    Published in Applied sciences (01-08-2022)
    “…Gene electrotransfer (GET) is a widely used method for nucleic acids’ delivery into cells. We explored, evaluated, and demonstrated the potential use of…”
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    Journal Article
  3. 3

    Gene Electrotransfer into Mammalian Cells Using Commercial Cell Culture Inserts with Porous Substrate by Vindiš, Tina, Blažič, Anja, Khayyat, Diaa, Potočnik, Tjaša, Sachdev, Shaurya, Rems, Lea

    Published in Pharmaceutics (01-09-2022)
    “…Gene electrotransfer is one of the main non-viral methods for intracellular delivery of plasmid DNA, wherein pulsed electric fields are used to transiently…”
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    Journal Article
  4. 4

    Revisiting the role of pulsed electric fields in overcoming the barriers to in vivo gene electrotransfer by Sachdev, Shaurya, Potočnik, Tjaša, Rems, Lea, Miklavčič, Damijan

    “…[Display omitted] Gene therapies are revolutionizing medicine by providing a way to cure hitherto incurable diseases. The scientific and technological advances…”
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  5. 5

    DNA-membrane complex formation during electroporation is DNA size-dependent by Sachdev, Shaurya, Feijoo Moreira, Sara, Keehnen, Yasmine, Rems, Lea, Kreutzer, Michiel T., Boukany, Pouyan E.

    “…Size of DNA molecules governs their interaction with the cell membrane during electroporation and their subsequent transport inside the cell. In order to…”
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    Journal Article
  6. 6

    Bridging the scales in high-throughput dielectrophoretic (bio-)particle separation in porous media by Pesch, Georg R., Lorenz, Malte, Sachdev, Shaurya, Salameh, Samir, Du, Fei, Baune, Michael, Boukany, Pouyan E., Thöming, Jorg

    Published in Scientific reports (11-07-2018)
    “…Dielectrophoresis (DEP) is a versatile technique for the solution of difficult (bio-)particle separation tasks based on size and material. Particle motion by…”
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    Journal Article
  7. 7

    DNA translocation to giant unilamellar vesicles during electroporation is independent of DNA size by Sachdev, Shaurya, Muralidharan, Aswin, Choudhary, Dipendra K, Perrier, Dayinta L, Rems, Lea, Kreutzer, Michiel T, Boukany, Pouyan E

    Published in Soft matter (2019)
    “…Delivery of naked DNA molecules into living cells via physical disruption of the membrane under electric pulses has potential biomedical applications ranging…”
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    Journal Article