Search Results - "Sachdeo, Rajesh C."
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Sustained Efficacy and Long‐term Safety of Oxcarbazepine: One‐year Open‐label Extension of a Study in Refractory Partial Epilepsy
Published in Epilepsia (Copenhagen) (01-09-2003)“…Purpose: To evaluate the long‐term efficacy, tolerability, and safety of oxcarbazepine (OXC) in medically refractory partial epilepsy. Methods: This study is…”
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On the Time Series K-Nearest Neighbor Classification of Abnormal Brain Activity
Published in IEEE transactions on systems, man and cybernetics. Part A, Systems and humans (01-11-2007)“…Epilepsy is one of the most common brain disorders, but the dynamical transitions to neurological dysfunctions of epilepsy are not well understood in current…”
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Novel Optimization Models for Abnormal Brain Activity Classification
Published in Operations research (01-11-2008)“…This paper proposes a new classification technique, called support feature machine (SFM), for multidimensional time-series data. The proposed technique was…”
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Efficacy and Tolerability of the New Antiepileptic Drugs, II: Treatment of Refractory Epilepsy: Report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society
Published in Epilepsia (Copenhagen) (01-05-2004)“…Purpose: To assess the evidence demonstrating efficacy, tolerability, and safety of seven new antiepileptic drugs (AEDs) [gabapentin (GBP), lamotrigine (LTG),…”
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Effects of oxcarbazepine on sodium concentration and water handling
Published in Annals of neurology (01-05-2002)“…Oxcarbazepine, a keto‐analogue of carbamazepine, was recently approved in the United States for the treatment of seizures of partial onset. Some patients…”
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Efficacy and Tolerability of the New Antiepileptic Drugs, I: Treatment of New‐Onset Epilepsy: Report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society
Published in Epilepsia (Copenhagen) (01-05-2004)“…Purpose: To assess the evidence demonstrating efficacy, tolerability, and safety of seven new antiepileptic drugs [AEDs; gabapentin (GBP), lamotrigine (LTG),…”
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Caffeinated beverages and decreased seizure control
Published in Seizure (London, England) (01-10-2003)“…Seizure control is often affected by seizure threshold lowering behaviours. In this case report, the authors address excessive caffeine ingestion from tea with…”
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Improved quality of life in patients with partial seizures after conversion to oxcarbazepine monotherapy
Published in Epilepsy & behavior (01-11-2006)“…Quality of life (QOL) was assessed in patients who switched to oxcarbazepine monotherapy because of the lack of efficacy or poor tolerability of their current…”
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Topiramate Monotherapy for Partial Onset Seizures
Published in Epilepsia (Copenhagen) (01-03-1997)“…Purpose: Evaluation of topiramate (TPM) as monotherapy in patients with uncontrolled partial onset seizures. Methods: A total of 48 patients were evaluated in…”
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Steady-state pharmacokinetics of topiramate and carbamazepine in patients with epilepsy during monotherapy and concomitant therapy
Published in Epilepsia (Copenhagen) (01-08-1996)“…We studied the steady-state pharmacokinetic profile of topiramate (TPM) as a function of dose and the effects of comedication with carbamazepine (CBZ). We…”
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Optimisation and data mining techniques for the screening of epileptic patients
Published in International journal of bioinformatics research and applications (2009)“…Identifying abnormalities or anomalies by visual inspection on neurophysiologic signals such as ElectroEncephaloGrams (EEGs), is extremely challenging. We…”
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Tiagabine in the Management of Postencephalitic Epilepsy and Impulse Control Disorder
Published in Epilepsy & behavior (01-04-2002)“…Rationale. Anticonvulsants are used as primary or adjunctive agents in the treatment of psychiatric disorders. γ-Aminobutyric acid (GABA) ergic modulation has…”
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Topiramate in Lennox–Gastaut Syndrome: Open‐Label Treatment of Patients Completing a Randomized Controlled Trial
Published in Epilepsia (Copenhagen) (01-01-2000)“…Purpose: The response to topiramate (TPM) as long‐term adjunctive therapy was evaluated in patients with Lennox‐Gastaut syndrome (LGS) in a long‐term,…”
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Topiramate efficacy in infancy
Published in Pediatric neurology (01-10-1998)“…Topiramate is a sulfamate-substituted monosaccharide that has demonstrated efficacy as an antiepileptic drug in adults with partial onset seizures. Experience…”
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Topiramate: Clinical profile in epilepsy
Published in Clinical pharmacokinetics (01-05-1998)“…Topiramate, a sulfamate-substituted monosaccharide, is a new antiepileptic drug (AED) approved as adjunctive therapy for partial-onset seizures in adults…”
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Topiramate and Phenytoin Pharmacokinetics During Repetitive Monotherapy and Combination Therapy to Epileptic Patients
Published in Epilepsia (Copenhagen) (01-10-2002)Get full text
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Felbamate
Published in The Lancet (British edition) (31-07-1993)Get more information
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Evaluation of the Potential Interaction Between Felbamate and Erythromycin in Patients with Epilepsy
Published in Journal of clinical pharmacology (01-02-1998)“…Effects of erythromycin on hepatic CYP450 3A4 isozymes can profoundly influence the metabolism of many therapeutic agents. An open‐label, randomized,…”
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