Search Results - "Sachani, Saqib S."
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Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells
Published in Nature communications (18-07-2018)“…Genomic imprinting is a phenomenon that restricts transcription to predominantly one parental allele. How this transcriptional duality is regulated is poorly…”
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Journal Article -
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Best of both worlds: A career in technology transfer and business development
Published in Developmental biology (01-03-2020)“…The current academic and business landscape does not provide a clear path for doctoral trainees graduating. Moreover, the fundamental need of the hour is…”
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Journal Article -
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A role for chromatin topology in imprinted domain regulation
Published in Biochemistry and cell biology (01-02-2016)“…Recently, many advancements in genome-wide chromatin topology and nuclear architecture have unveiled the complex and hidden world of the nucleus, where…”
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Journal Article -
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Microinjection manipulations in the elucidation of Xenopus brain development
Published in Methods in molecular biology (Clifton, N.J.) (2014)“…Microinjection has a long and distinguished history in Xenopus and has been used to introduce a surprisingly diverse array of agents into embryos by both…”
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Journal Article -
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Role of Six3 and Pax6 in regulating the gene networks involved in vertebrate eye development
Published 01-01-2011“…Xenopus eye field transcription factors display a dynamic and overlapping expression pattern but their signaling hierarchy is unclear. Current signaling models…”
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Dissertation