Search Results - "Sachan, Nita"

FoxO transcription factors activate Akt and attenuate insulin signaling in heart by inhibiting protein phosphatases by Ni, Yan G, Wang, Na, Cao, Dian J, Sachan, Nita, Morris, David J, Gerard, Robert D, Kuro-o, Makoto, Rothermel, Beverly A, Hill, Joseph A

“…Insulin resistance and metabolic syndrome are rapidly expanding public health problems. Acting through the PI3K/Akt pathway, insulin and insulin-like growth…”
Get full text

Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling by NI, Yan G, BERENJI, Kambeez, GERARD, Robert D, ROTHERMEL, Beverly A, HILL, Joseph A, NA WANG, OH, Misook, SACHAN, Nita, DEY, Asim, JUN CHENG, GUANGRONG LU, MORRIS, David J, CASTRILLON, Diego H

“…Cellular hypertrophy requires coordinated regulation of progrowth and antigrowth mechanisms. In cultured neonatal cardiomyocytes, Foxo transcription factors…”
Get full text

Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo by Misra, Chaitali, Sachan, Nita, McNally, Caryn Rothrock, Koenig, Sara N, Nichols, Haley A, Guggilam, Anuradha, Lucchesi, Pamela A, Pu, William T, Srivastava, Deepak, Garg, Vidu

“…Defects of atrial and ventricular septation are the most frequent form of congenital heart disease, accounting for almost 50% of all cases. We previously…”
Get full text

The Down Syndrome Critical Region Protein RCAN1 Regulates Long-Term Potentiation and Memory via Inhibition of Phosphatase Signaling by Hoeffer, Charles A, Dey, Asim, Sachan, Nita, Wong, Helen, Patterson, Richard J, Shelton, John M, Richardson, James A, Klann, Eric, Rothermel, Beverly A

“…Regulator of calcineurin 1 (RCAN1/MCIP1/DSCR1) regulates the calmodulin-dependent phosphatase calcineurin. Because it is located on human chromosome 21, RCAN1…”
Get full text

Calcineurin and its regulator, RCAN1, confer time-of-day changes in susceptibility of the heart to ischemia/reperfusion by Rotter, David, Grinsfelder, D. Bennett, Parra, Valentina, Pedrozo, Zully, Singh, Sarvjeet, Sachan, Nita, Rothermel, Beverly A

“…Abstract Many important components of the cardiovascular system display circadian rhythmicity. In both humans and mice, cardiac damage from…”
Get full text

Abstract P275: Time-of-Day--Dependent Variation in Myocardial Ischemia/Reperfusion Injury Is Lost in Mice Lacking the Regulator of Calcineurin 1 Gene by Grinsfelder, D B, Rotter, David, Sachan, Nita, Rothermel, Beverly A

“…Abstract only Many important components of the cardiovascular system display circadian rhythmicity. In humans, the incidence of myocardial infarction peaks in…”
Get full text

Sustained Hemodynamic Stress Disrupts Normal Circadian Rhythms in Calcineurin-Dependent Signaling and Protein Phosphorylation in the Heart by Sachan, Nita, Dey, Asim, Rotter, David, Grinsfelder, D Bennett, Battiprolu, Pavan K, Sikder, Devanjan, Copeland, Victoria, Oh, Misook, Bush, Erik, Shelton, John M, Bibb, James A, Hill, Joseph A, Rothermel, Beverly A

“…RATIONALE:Despite overwhelming evidence of the importance of circadian rhythms in cardiovascular health and disease, little is known regarding the circadian…”
Get full text

Reactive oxygen species regulate alkaloid metabolism in undifferentiated N. tabacum cells by Sachan, Nita, Rogers, Dennis T, Yun, Kil-Young, Littleton, John M, Falcone, Deane L

“…Plants produce an immense number of natural products and undifferentiated cells from various plant tissues have long been considered an ideal source for their…”
Get full text

Abstract 3442: Normal Circadian Rhythms In Calcineurin-dependent Signaling And Protein Phosphorylation Are Disrupted In Heart Failure by Dey, Asim, Sachan, Nita, Oh, Misook, Hill, Joseph A, Rothermel, Beverly A

“…Abstract only Many important cardiovascular factors, including metabolism, heart rate, blood pressure, and hormone release, oscillate over a 24-hour period. In…”
Get full text

Wound-induced gene expression of putrescine N-methyltransferase in leaves of Nicotiana tabacum by Sachan, Nita, Falcone, Deane L

“…Putrescine N-methyltransferase (PMT) catalyzes the first committed step in the biosynthesis of pyrrolinium ring-containing alkaloids. Earlier studies have…”
Get full text