Search Results - "Sacchetti, Lucia"

Orexin-A represses satiety-inducing POMC neurons and contributes to obesity via stimulation of endocannabinoid signaling by Morello, Giovanna, Imperatore, Roberta, Palomba, Letizia, Finelli, Carmine, Labruna, Giuseppe, Pasanisi, Fabrizio, Sacchetti, Lucia, Buono, Lorena, Piscitelli, Fabiana, Orlando, Pierangelo, Di Marzo, Vincenzo, Cristino, Luigia

“…In the hypothalamic arcuate nucleus (ARC), proopiomelanocortin (POMC) neurons and the POMC-derived peptide α–melanocyte-stimulating hormone (α-MSH) promote…”
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16S rRNA of Mucosal Colon Microbiome and CCL2 Circulating Levels Are Potential Biomarkers in Colorectal Cancer by Nardelli, Carmela, Granata, Ilaria, Nunziato, Marcella, Setaro, Mario, Carbone, Fortunata, Zulli, Claudio, Pilone, Vincenzo, Capoluongo, Ettore Domenico, De Palma, Giovanni Domenico, Corcione, Francesco, Matarese, Giuseppe, Salvatore, Francesco, Sacchetti, Lucia

“…Colorectal cancer (CRC) is one of the most common malignancies in the Western world and intestinal dysbiosis might contribute to its pathogenesis. The mucosal…”
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MicroRNA-449a overexpression, reduced NOTCH1 signals and scarce goblet cells characterize the small intestine of celiac patients by Capuano, Marina, Iaffaldano, Laura, Tinto, Nadia, Montanaro, Donatella, Capobianco, Valentina, Izzo, Valentina, Tucci, Francesca, Troncone, Giancarlo, Greco, Luigi, Sacchetti, Lucia

“…MiRNAs play a relevant role in regulating gene expression in a variety of physiological and pathological conditions including autoimmune disorders. MiRNAs are…”
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High Frequency of Haplotype HLA-DQ7 in Celiac Disease Patients from South Italy: Retrospective Evaluation of 5,535 Subjects at Risk of Celiac Disease by Tinto, Nadia, Cola, Arturo, Piscopo, Chiara, Capuano, Marina, Galatola, Martina, Greco, Luigi, Sacchetti, Lucia

“…Celiac disease (CD) has a strong genetic component mainly due to HLA DQ2/DQ8 encoding genes. However, a minority of CD patients are DQ2/DQ8-negative. To…”
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Characterization of the Duodenal Mucosal Microbiome in Obese Adult Subjects by 16S rRNA Sequencing by Nardelli, Carmela, Granata, Ilaria, D'Argenio, Valeria, Tramontano, Salvatore, Compare, Debora, Guarracino, Mario Rosario, Nardone, Gerardo, Pilone, Vincenzo, Sacchetti, Lucia

“…The gut microbiota may have an impact on obesity. To date, the majority of studies in obese patients reported microbiota composition in stool samples. The aim…”
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Age-Related Reference Intervals of the Main Biochemical and Hematological Parameters in C57BL/6J, 129SV/EV and C3H/HeJ Mouse Strains by Mazzaccara, Cristina, Labruna, Giuseppe, Cito, Gennaro, Scarfò, Marzia, De Felice, Mario, Pastore, Lucio, Sacchetti, Lucia

“…Although the mouse is the animal model most widely used to study the pathogenesis and treatment of human diseases, reference values for biochemical parameters…”
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Immune-metabolic profiling of anorexic patients reveals an anti-oxidant and anti-inflammatory phenotype by Omodei, Daniela, Pucino, Valentina, Labruna, Giuseppe, Procaccini, Claudio, Galgani, Mario, Perna, Francesco, Pirozzi, Daniele, De Caprio, Carmela, Marone, Gianni, Fontana, Luigi, Contaldo, Franco, Pasanisi, Fabrizio, Matarese, Giuseppe, Sacchetti, Lucia

“…Abstract Context Anorexia nervosa (AN) is an excessive form of calorie restriction (CR) associated with pathological weight loss and alterations of the immune…”
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Warfarin anticoagulant therapy: a Southern Italy pharmacogenetics-based dosing model by Mazzaccara, Cristina, Conti, Valeria, Liguori, Rosario, Simeon, Vittorio, Toriello, Mario, Severini, Angelo, Perricone, Corrado, Meccariello, Alfonso, Meccariello, Pasquale, Vitale, Dino Franco, Filippelli, Amelia, Sacchetti, Lucia

“…Warfarin is the most frequently prescribed anticoagulant worldwide. However, warfarin therapy is associated with a high risk of bleeding and thromboembolic…”
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Duodenal Metatranscriptomics to Define Human and Microbial Functional Alterations Associated with Severe Obesity: A Pilot Study by Granata, Ilaria, Nardelli, Carmela, D’Argenio, Valeria, Tramontano, Salvatore, Compare, Debora, Guarracino, Mario Rosario, Nardone, Gerardo, Pilone, Vincenzo, Sacchetti, Lucia

“…Obesity is a multifactorial disorder, and the gut microbiome has been suggested to contribute to its onset. In order to better clarify the role of the…”
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Genetic analysis resolves differential diagnosis of a familial syndromic dilated cardiomyopathy: A new case of Alström syndrome by Lombardo, Barbara, D'Argenio, Valeria, Monda, Emanuele, Vitale, Andrea, Caiazza, Martina, Sacchetti, Lucia, Pastore, Lucio, Limongelli, Giuseppe, Frisso, Giulia, Mazzaccara, Cristina

“…Background Syndromic dilated cardiomyopathy (DCM) includes a group of complex disorders with a very heterogeneous genetic etiology, leading…”
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Changes in the MicroRNA Profile Observed in the Subcutaneous Adipose Tissue of Obese Patients after Laparoscopic Adjustable Gastric Banding by Salvatore, Francesco, Sacchetti, Lucia, Buono, Pasqualina, Dodaro, Concetta, Carlomagno, Nicola, Ferrigno, Maddalena, Labruna, Giuseppe, Pilone, Vincenzo, Iaffaldano, Laura, Nardelli, Carmela, Forestieri, Pietro

“…Background. Laparoscopic adjustable gastric banding (LAGB) results in significant lasting weight loss and improved metabolism in obese patients. To evaluate…”
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Glucokinase (GCK) mutations and their characterization in MODY2 children of southern Italy by Capuano, Marina, Garcia-Herrero, Carmen Maria, Tinto, Nadia, Carluccio, Carla, Capobianco, Valentina, Coto, Iolanda, Cola, Arturo, Iafusco, Dario, Franzese, Adriana, Zagari, Adriana, Navas, Maria Angeles, Sacchetti, Lucia

“…Type 2 Maturity Onset Diabetes of the Young (MODY2) is a monogenic autosomal disease characterized by a primary defect in insulin secretion and hyperglycemia…”
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The Cause of Death of a Child in the 18th Century Solved by Bone Microbiome Typing Using Laser Microdissection and Next Generation Sequencing by D'Argenio, Valeria, Torino, Marielva, Precone, Vincenza, Casaburi, Giorgio, Esposito, Maria Valeria, Iaffaldano, Laura, Malapelle, Umberto, Troncone, Giancarlo, Coto, Iolanda, Cavalcanti, Paolina, De Rosa, Gaetano, Salvatore, Francesco, Sacchetti, Lucia

“…The history of medicine abounds in cases of mysterious deaths, especially by infectious diseases, which were probably unresolved because of the lack of…”
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Promelaxin Microenemas Are Non-inferior to Oral Polyethylene Glycol for the Treatment of Functional Constipation in Young Children: A Randomized Clinical Trial by Strisciuglio, Caterina, Coppola, Vincenzo, Russo, Marina, Tolone, Carlo, Marseglia, Gian Luigi, Verrotti, Alberto, Caimmi, Silvia, Caloisi, Claudia, D'Argenio, Valeria, Sacchetti, Lucia, Staiano, Annamaria

“…Background: Polyethylene glycol (PEG) is recommended as first-line treatment of pediatric functional constipation. However, the oral route of administration is…”
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Connectivity Between Posterior Parietal Cortex and Ipsilateral Motor Cortex Is Altered in Schizophrenia by Koch, Giacomo, Ribolsi, Michele, Mori, Francesco, Sacchetti, Lucia, Codecà, Claudia, Rubino, Ivo Alex, Siracusano, Alberto, Bernardi, Giorgio, Centonze, Diego

“…Background Recent advances have highlighted the hypothesis of schizophrenia as a disorder causing defective connectivity among distinct cortical regions…”
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Mitochondrial diabetes in children: seek and you will find it by Mazzaccara, Cristina, Iafusco, Dario, Liguori, Rosario, Ferrigno, Maddalena, Galderisi, Alfonso, Vitale, Domenico, Simonelli, Francesca, Landolfo, Paolo, Prisco, Francesco, Masullo, Mariorosario, Sacchetti, Lucia

“…Maternally Inherited Diabetes and Deafness (MIDD) is a rare form of diabetes due to defects in mitochondrial DNA (mtDNA). 3243 A>G is the mutation most…”
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Improving the estimation of celiac disease sibling risk by non-HLA genes by Izzo, Valentina, Pinelli, Michele, Tinto, Nadia, Esposito, Maria Valeria, Cola, Arturo, Sperandeo, Maria Pia, Tucci, Francesca, Cocozza, Sergio, Greco, Luigi, Sacchetti, Lucia

“…Celiac Disease (CD) is a polygenic trait, and HLA genes explain less than half of the genetic variation. Through large GWAs more than 40 associated non-HLA…”
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Corrigendum to “Sequence Analysis of the UCP1 Gene in a Severe Obese Population from Southern Italy” by Sacchetti, Lucia, Contaldo, Franco, Finelli, Carmine, Nardelli, Carmela, Fortunato, Giuliana, Pasanisi, Fabrizio, Labruna, Giuseppe, Farinaro, Eduardo

“…In the article titled “Sequence Analysis of the UCP1 Gene in a Severe Obese Population from Southern Italy” [1], the fifth author, Carmine Finelli, is not…”
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Setup of Quantitative PCR for Oral Neisseria spp. Evaluation in Celiac Disease Diagnosis by Esposito, Maria Valeria, Nardelli, Carmela, Granata, Ilaria, Pagliuca, Chiara, D'Argenio, Valeria, Russo, Ilaria, Guarracino, Mario Rosario, Salvatore, Paola, Del Vecchio Blanco, Giovanna, Ciacci, Carolina, Sacchetti, Lucia

“…Coeliac disease (CD) is a multifactorial autoimmune disorder and gut dysbiosis contributes to its pathogenesis. We previously profiled by 16S rRNA sequencing…”
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Glucokinase gene mutations: structural and genotype-phenotype analyses in MODY children from South Italy by Tinto, Nadia, Zagari, Adriana, Capuano, Marina, De Simone, Alfonso, Capobianco, Valentina, Daniele, Gerardo, Giugliano, Michela, Spadaro, Raffaella, Franzese, Adriana, Sacchetti, Lucia

“…Maturity onset diabetes of the young type 2 (or GCK MODY) is a genetic form of diabetes mellitus provoked by mutations in the glucokinase gene (GCK). We…”
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