Search Results - "Sabry, Amira"
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Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart
Published in Proceedings of the National Academy of Sciences - PNAS (14-08-2018)“…Smyd1, a muscle-specific histone methyltransferase, has established roles in skeletal and cardiac muscle development, but its role in the adult heart remains…”
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Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1
Published in PloS one (23-06-2020)“…The transcriptional regulatory machinery in mitochondrial bioenergetics is complex and is still not completely understood. We previously demonstrated that the…”
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Multiple Levels of PGC-1α Dysregulation in Heart Failure
Published in Frontiers in cardiovascular medicine (30-01-2020)“…Metabolic adaption is crucial for the heart to sustain its contractile activity under various physiological and pathological conditions. At the molecular…”
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Conduction in the right and left ventricle is differentially regulated by protein kinases and phosphatases: implications for arrhythmogenesis
Published in American journal of physiology. Heart and circulatory physiology (01-06-2019)“…The "stress" kinases cAMP-dependent protein kinase (PKA) and calcium/calmodulin-dependent protein kinase II (CaMKII), phosphorylate the Na channel Nav1.5…”
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PERM1 regulates energy metabolism in the heart via ERRα/PGC-1α axis
Published in Frontiers in cardiovascular medicine (07-11-2022)“…PERM1 is a striated muscle-specific regulator of mitochondrial bioenergetics. We previously demonstrated that PERM1 is downregulated in the failing heart and…”
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Efficacy of single phototherapy with low-cost reflective sheets versus single phototherapy alone in mild-to-moderate unconjugated hyperbilirubinaemia in full-term neonates
Published in Paediatrics and international child health (03-07-2021)“…An economical alternative method of increasing the light intensity of phototherapy for neonatal jaundice is the use of reflective sheets placed on the sides of…”
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A De Novo Optimized Cell-Free System for the Expression of Soluble and Active Human Tumor Necrosis Factor-Alpha
Published in Biology (Basel, Switzerland) (19-01-2022)“…Cell-free (in vitro) expression is a robust alternative platform to the cell-based (in vivo) system for recombinant protein production. Tumor necrosis…”
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On Idle Possibilities and Missed Chances: Refugee Rights in Egypt
Published in Refugee survey quarterly (07-09-2023)“…Abstract This article investigates the rights of refugees in Egypt and the numerous barriers that exist that prevent their enjoyment. Specifically, the article…”
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Diagnostic Role of CD64 on Different Immune Cells in Early Diagnosis of Neonatal Sepsis
Published in The Egyptian journal of immunology (01-06-2018)“…Neonatal sepsis is an important cause of morbidity and mortality among neonates. Early diagnosis leads to better prognosis. CD64 can be used as an early marker…”
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Anthropometric Measurements for Egyptian Preterms at Birth: Single Center Pilot Study
Published in Pediatric Sciences Journal (01-07-2022)“…ackground: Assessment of fetal growth is a major part of antenatal and perinatal care. It reflects the intrauterine environment quality. Developed countries…”
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Clinical Predictors for Outcome of Continuous Positive Airway Pressure in Respiratory Distress Syndrome in Preterms: Single Center Study
Published in Pediatric Sciences Journal (01-01-2023)“…Background: Applying mechanical ventilation (MV) to premature lungs carries many risks, up to lung injury and bronchopulmonary dysplasia. Stabilization with…”
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Care Bundle Application Decreases The Frequency and Severity of Intraventricular Hemorrhage in Preterm Neonates: Single Center Study
Published in Pediatric Sciences Journal (01-07-2022)“…Background: Intraventricular hemorrhage (IVH) is a severe complication in preterm babies admitted to Neonatal Intensive Care Units (NICU). Advanced stages of…”
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5990 Effect of nutritional assessment, counselling and supplementation on growth catch-up of preterm infants after NICU discharge, a single center study
Published in Archives of disease in childhood (01-08-2024)“…ObjectivesTo assess the nutritional status of premature infants using clinical, anthropometric and laboratory parameters during the first 90 days of life after…”
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Meta Analysis Study of Complications Following Repair of Mid Penile Hypospadius using Different Surgical Techniques
Published in QJM : An International Journal of Medicine (01-10-2021)“…Abstract Background Hypospadias is one of the most common congenital defects affecting the external male genitalia. The incidence is 1 in 250 male newborns,…”
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Abstract 286: Smyd1 is Required for Cell Survival During Glucose Deprivation
Published in Circulation research (02-08-2019)“…Abstract only Our recent study demonstrated that the histone methyltransferase Smyd1 positively regulates cardiac metabolism through transcriptional control of…”
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Abstract 418: Perm1 is a Novel Regulator of Mitochondrial Energetics in Cardiomyocytes
Published in Circulation research (03-08-2018)“…Abstract only Mitochondrial oxidative metabolism and energy transduction pathways are critical for cardiac function. The expression of genes important for…”
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Abstract 289: Perm1 is a Novel Regulator of Cardiac Energetics and Function
Published in Circulation research (31-07-2020)“…Abstract only Regulation of mitochondrial energetics is key to maintain cardiac function. Perm1 ( P GC-1 and E RR- r egulator, m uscle 1 ) was previously shown…”
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Mesenchymal stromal cells and TGF-β1 in tracheal aspirate of premature infants: early predictors for bronchopulmonary dysplasia?
Published in Journal of perinatal medicine (27-05-2019)“…Background The pathogenesis of bronchopulmonary dysplasia (BPD) includes arrest of alveolar septation and enhanced fibrosis. We hypothesized that mesenchymal…”
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Functionality of intrinsic disorder in tumor necrosis factor-[alpha] and its receptors
Published in The FEBS journal (01-11-2017)“…Tumor necrosis factor-[alpha] (TNF-[alpha]) is a pleiotropic inflammatory cytokine that exerts potent cytotoxic effects on solid tumor cells, while not…”
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