Search Results - "Sabra, M."
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Circadian disruption and human health: A bidirectional relationship
Published in The European journal of neuroscience (01-01-2020)“…Circadian rhythm disorders have been classically associated with disorders of abnormal timing of the sleep–wake cycle, however circadian dysfunction can play a…”
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Light exposure during sleep impairs cardiometabolic function
Published in Proceedings of the National Academy of Sciences - PNAS (22-03-2022)“…SignificanceAmbient nighttime light exposure is implicated as a risk factor for adverse health outcomes, including cardiometabolic disease. However, the…”
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Universal method for robust detection of circadian state from gene expression
Published in Proceedings of the National Academy of Sciences - PNAS (25-09-2018)“…Circadian clocks play a key role in regulating a vast array of biological processes, with significant implications for human health. Accurate assessment of…”
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Obstructive Sleep Apnea and Risk of COVID-19 Infection, Hospitalization and Respiratory Failure
Published in Sleep & breathing (01-06-2021)“…Purpose To study the relationship between OSA and risk of COVID-19 infection and disease severity, identified by the need for hospitalization and progression…”
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Melanopsin-dependent phototransduction is impaired in delayed sleep–wake phase disorder and sighted non–24-hour sleep–wake rhythm disorder
Published in Sleep (New York, N.Y.) (01-02-2021)“…Abstract Study Objectives The circadian system must perform daily adjustments to align sleep–wake and other physiologic rhythms with the environmental…”
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Circadian Disruption Associated with Alzheimer’s Disease
Published in Current neurology and neuroscience reports (01-04-2017)“…Alzheimer’s disease (AD) is increasing in prevalence and has a significant impact on caregivers and the healthcare system. One of the many physiologic process…”
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Multivariate analysis reveals genetic associations of the resting default mode network in psychotic bipolar disorder and schizophrenia
Published in Proceedings of the National Academy of Sciences - PNAS (13-05-2014)“…The brain’s default mode network (DMN) is highly heritable and is compromised in a variety of psychiatric disorders. However, genetic control over the DMN in…”
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Pharmacotherapy of Apnea by Cannabimimetic Enhancement, the PACE Clinical Trial: Effects of Dronabinol in Obstructive Sleep Apnea
Published in Sleep (New York, N.Y.) (01-01-2018)“…Abstract Study Objectives There remains an important and unmet need for fully effective and acceptable treatments in obstructive sleep apnea (OSA). At present,…”
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Workshop report. Circadian rhythm sleep–wake disorders: gaps and opportunities
Published in Sleep (New York, N.Y.) (01-05-2021)“…Abstract This White Paper presents the results from a workshop cosponsored by the Sleep Research Society (SRS) and the Society for Research on Biological…”
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Thyroid cancer incidence patterns in the United States by histologic type, 1992-2006
Published in Thyroid (New York, N.Y.) (01-02-2011)“…The increasing incidence of thyroid cancer in the United States is well documented. In this study, we assessed the incidence patterns by histologic type…”
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Non–24-hour Sleep-Wake Rhythm Disorder
Published in Neurologic clinics (01-08-2019)“…Non–24-hour sleep-wake rhythm disorder is a circadian rhythm sleep-wake disorder characterized by an inability to entrain to the 24-hour environment. Patients…”
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Clinical Outcomes and Molecular Profile of Differentiated Thyroid Cancers With Radioiodine-Avid Distant Metastases
Published in The journal of clinical endocrinology and metabolism (01-05-2013)“…Background: Radioiodine (RAI) remains the mainstay of therapy for RAI-avid (RAIA) distant metastatic thyroid carcinoma. We previously demonstrated that…”
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Chronic sleep disturbance and neural injury: links to neurodegenerative disease
Published in Nature and Science of Sleep (01-01-2016)“…Sleep-wake disruption is frequently observed and often one of the earliest reported symptoms of many neurodegenerative disorders. This provides insight into…”
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Stress-Induced Behavioral Quiescence and Abnormal Rest-Activity Rhythms During Critical Illness
Published in Critical care medicine (01-06-2020)“…OBJECTIVES:To characterize acute alterations of circadian and ultradian rest-activity rhythms in critically ill patients and their association with brain…”
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Sleep Timing, Stability, and BP in the Sueño Ancillary Study of the Hispanic Community Health Study/Study of Latinos
Published in Chest (01-01-2019)“…Timing and stability of the sleep-wake cycle are potential modifiable risk factors for cardiometabolic disease. The aim of this study was to evaluate the…”
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Circadian Rhythm Sleep-Wake Disorders
Published in The Psychiatric clinics of North America (01-12-2015)“…The circadian system regulates the timing and expression of nearly all biological processes, most notably, the sleep-wake cycle, and disruption of this system…”
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Strengthening sleep-autonomic interaction via acoustic enhancement of slow oscillations
Published in Sleep (New York, N.Y.) (01-05-2019)“…Slow-wave sleep (SWS) is important for overall health since it affects many physiological processes including cardio-metabolic function. Sleep and autonomic…”
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Circadian Rhythms: Implications for Health and Disease
Published in Neurologic clinics (01-08-2019)“…Circadian rhythms are present in nearly all organisms studied, and are present throughout the human body. The proper coordination of these rhythms, both within…”
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Ivor Lewis vs Mckeown esophagectomy: analysis of operative outcomes from the ACS NSQIP database
Published in General thoracic and cardiovascular surgery (01-04-2020)“…Objectives Ivor Lewis and McKeown esophagectomy are common techniques to treat esophageal cancer. In this study, we aim to compare these two approaches. Method…”
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