Search Results - "Sabourin, Jean–Christophe"

Impact of FcγRIIa-FcγRIIIa Polymorphisms and KRAS Mutations on the Clinical Outcome of Patients With Metastatic Colorectal Cancer Treated With Cetuximab Plus Irinotecan by BIBEAU, Frédéric, LOPEZ-CRAPEZ, Evelyne, SABOURIN, Jean-Christophe, BOISSIERE-MICHOT, Florence, DI FIORE, Frédénc, THEZENAS, Simon, YCHOU, Marc, BLANCHARD, France, LAMY, Aude, PENAULT-LLORCA, Frédérique, FREBOURG, Thierry, MICHEL, Pierre

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On the relevance of a testing algorithm for the detection of ROS1 -rearranged lung adenocarcinomas by Mescam-Mancini, Lénaïg, Lantuéjoul, Sylvie, Moro-Sibilot, Denis, Rouquette, Isabelle, Souquet, Pierre-Jean, Audigier-Valette, Clarisse, Sabourin, Jean-Christophe, Decroisette, Chantal, Sakhri, Linda, Brambilla, Elisabeth, McLeer-Florin, Anne

“…Abstract Objectives ROS1 proto-oncogene translocations define a new molecular subgroup in non-small cell lung cancers (NSCLC) and are associated with a…”
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An improved assay for detection of theranostic gene translocations and MET exon 14 skipping in thoracic oncology by Piton, Nicolas, Lanic, Marie-Delphine, Marguet, Florent, Lamy, Aude, Blanchard, France, Guisier, Florian, Viennot, Mathieu, Salaün, Mathieu, Thiberville, Luc, Jardin, Fabrice, Sabourin, Jean-Christophe, Ruminy, Philippe

“…Theranostic translocations may be difficult to detect by routine techniques, especially when specimens are exiguous. We recently demonstrated in a series of…”
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A case of Pseudomyxoma Peritonei of an unexpected origin by Csanyi-Bastien, Marie, Blanchard, France, Lamy, Aude, Sabourin, Jean-Christophe

“…Pseudomyxoma peritonei (PMP) is a complex and partially understood disease defined by mucin deposits in the peritoneal cavity, mostly of appendiceal origin…”
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Molecular analysis of peripheral non-squamous non-small cell lung cancer sampled by radial EBUS by Guisier, Florian, Salaün, Mathieu, Lachkar, Samy, Lamy, Aude, Piton, Nicolas, Obstoy, Bérengère, Sabourin, Jean-Christophe, Thiberville, Luc

“…Background and objective Treatment optimization of non‐squamous non‐small‐cell lung cancers (nonSq‐NSCLC) relies on the molecular analysis of the tumour. We…”
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Assessment of endobronchial ultrasound‐guided bronchoscopy (EBUS) intranodal forceps biopsy added to EBUS 19‐gauge transbronchial needle aspiration: A blinded pathology panel analysis by Lachkar, Samy, Faur, Quentin, Marguet, Florent, Veresezan, Liana, Bubenheim, Michael, Salaün, Mathieu, Thiberville, Luc, Sabourin, Jean‐Christophe, Guisier, Florian, Piton, Nicolas

“…Background Endobronchial ultrasound‐guided (EBUS) transbronchial needle aspiration (TBNA) has significantly improved the diagnostic workup for intrathoracic…”
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Predictive molecular pathology in non–small cell lung cancer in France: The past, the present and the perspectives by Hofman, Paul, Rouleau, Etienne, Sabourin, Jean‐Christophe, Denis, Marc, Deleuze, Jean‐François, Barlesi, Fabrice, Laurent‐Puig, Pierre

“…The advent of molecular targets for novel therapeutics in oncology, notably for non–small cell lung carcinoma (NSCLC), led the French National Cancer Institute…”
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An unusual case of primary splenic soft part alveolar sarcoma: case report and review of the literature with emphasis on the spectrum of TFE3-associated neoplasms by Guérin, René, Menard, Anne-Lise, Angot, Emilie, Piton, Nicolas, Vera, Pierre, Schwarz, Lilian, Sabourin, Jean-Christophe, Laé, Marick, Thiébaut, Pierre-Alain

“…Alveolar soft part sarcoma is a rare tumour of soft tissues, mostly localized in muscles or deep soft tissues of the extremities. In rare occasions, this…”
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Mapping of bowel occult microscopic endometriosis implants surrounding deep endometriosis nodules infiltrating the bowel by Badescu, Alexandra, M.D, Roman, Horace, M.D., Ph.D, Aziz, Moutaz, M.D, Puscasiu, Lucian, M.D., Ph.D, Molnar, Claudiu, M.D., Ph.D, Huet, Emmanuel, M.D, Sabourin, Jean-Christophe, M.D., Ph.D, Stolnicu, Simona, M.D., Ph.D

“…Objective To provide a mapping of bowel occult microscopic endometriosis implants from colorectal specimens removed from patients who had undergone colorectal…”
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Repeated Autologous Bone Marrow‐Derived Mesenchymal Stem Cell Injections Improve Radiation‐Induced Proctitis in Pigs by Linard, Christine, Busson, Elodie, Holler, Valerie, Strup-Perrot, Carine, Lacave-Lapalun, Jean-Victor, Lhomme, Bruno, Prat, Marie, Devauchelle, Patrick, Sabourin, Jean-Christophe, Simon, Jean-Marc, Bonneau, Michel, Lataillade, Jean-Jacques, Benderitter, Marc

“…Using a preclinical pig model of proctitis, this study investigated the effect of autologous bone marrow‐derived mesenchymal stem cells (MSCs) on high‐dose…”
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First Comparison between [18f]-FMISO and [18f]-Faza for Preoperative Pet Imaging of Hypoxia in Lung Cancer by Thureau, Sébastien, Piton, Nicolas, Gouel, Pierrick, Modzelewski, Romain, Dujon, Antoine, Baste, Jean-Marc, Melki, Jean, Rinieri, Philippe, Peillon, Christophe, Rastelli, Olivier, Lequesne, Justine, Hapdey, Sébastien, Sabourin, Jean-Christophe, Bohn, Pierre, Vera, Pierre

“…Hypoxic areas are typically resistant to treatment. However, the fluorine-18-fluoroazomycin-arabinoside (FAZA) and fluorine 18 misonidazole (FMISO) tracers…”
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TLR3 as a Biomarker for the Therapeutic Efficacy of Double-stranded RNA in Breast Cancer by SALAUN, Bruno, ZITVOGEL, Laurence, GOUBAR, Aicha, LEBECQUE, Serge, PIERRES, Michel, RIMOLDI, Donata, ROMERO, Pedro, ANDRE, Fabrice, ASSELIN-PATUREL, Carine, MOREL, Yannis, CHEMIN, Karine, DUBOIS, Clarisse, MASSACRIER, Catherine, CONFORTI, Rosa, PIERRE CHENARD, Marie, SABOURIN, Jean-Christophe

“…The discovery of a targeted therapeutic compound along with its companion predictive biomarker is a major goal of clinical development for a personalized…”
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Heterogeneity of Mismatch Repair Status and Microsatellite Instability between Primary Tumour and Metastasis and Its Implications for Immunotherapy in Colorectal Cancers by Evrard, Camille, Messina, Stéphane, Sefrioui, David, Frouin, Éric, Auriault, Marie-Luce, Chautard, Romain, Zaanan, Aziz, Jaffrelot, Marion, De La Fouchardière, Christelle, Aparicio, Thomas, Coriat, Romain, Godet, Julie, Silvain, Christine, Randrian, Violaine, Sabourin, Jean-Christophe, Guimbaud, Rosine, Miquelestorena-Standley, Elodie, Lecomte, Thierry, Moulin, Valérie, Karayan-Tapon, Lucie, Tachon, Gaëlle, Tougeron, David

“…Deficient mismatch repair system (dMMR)/microsatellite instability (MSI) is found in about 5% of metastatic colorectal cancers (mCRCs) with a major therapeutic…”
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Metastatic colorectal cancer KRAS genotyping in routine practice: results and pitfalls by Lamy, Aude, Blanchard, France, Le Pessot, Florence, Sesboüé, Richard, Di Fiore, Frédéric, Bossut, Jessie, Fiant, Elodie, Frébourg, Thierry, Sabourin, Jean-Christophe

“…KRAS genotyping is mandatory before anti-epidermal growth factor receptor monoclonal antibody therapy in metastatic colorectal cancer, which is the second…”
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In vivo evidence for an endothelium-dependent mechanism in radiation-induced normal tissue injury by Rannou, Emilie, François, Agnès, Toullec, Aurore, Guipaud, Olivier, Buard, Valérie, Tarlet, Georges, Mintet, Elodie, Jaillet, Cyprien, Iruela-Arispe, Maria Luisa, Benderitter, Marc, Sabourin, Jean-Christophe, Milliat, Fabien

“…The pathophysiological mechanism involved in side effects of radiation therapy and especially the role of the endothelium remains unclear. Previous results…”
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Endothelial Hey2 deletion reduces endothelial-to-mesenchymal transition and mitigates radiation proctitis in mice by Mintet, Elodie, Lavigne, Jérémy, Paget, Vincent, Tarlet, Georges, Buard, Valérie, Guipaud, Olivier, Sabourin, Jean-Christophe, Iruela-Arispe, Maria-Luisa, Milliat, Fabien, François, Agnès

“…The current study evaluated the role of Hey2 transcription factor in radiation-induced endothelial-to-mesenchymal transition (EndoMT) and its impact on…”
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ERCC1 Codon 118 Polymorphism Is a Predictive Factor for the Tumor Response to Oxaliplatin/5-Fluorouracil Combination Chemotherapy in Patients with Advanced Colorectal Cancer by VIGUIER, Jérome, BOIGE, Valérie, MIQUEL, Catherine, POCARD, Marc, GIRAUDEAU, Bruno, SABOUNN, Jean-Christophe, DUCREUX, Michel, SARASIN, Alain, PRAZ, Francoise

“…Purpose: The aim of our study was to assess whether the polymorphism of the nucleotide excision repair enzyme, excision repair cross-complementing rodent…”
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Circulating tumor cell isolation： the assets of filtration methods with polycarbonate track-etched filters by Dolfus, Claire, Piton, Nicolas, Toure, Emmanuel, Sabourin, Jean-Christophe

“…Circulating tumor cells （CTCs） arise from primary or secondary tumors and enter the bloodstream by active or passive intravasation. Given the low number of…”
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Characterization of an adaptive immune response in microsatellite-instable colorectal cancer by Boissière-Michot, Florence, Lazennec, Gwendal, Frugier, Hélène, Jarlier, Marta, Roca, Lise, Duffour, Jacqueline, Du Paty, Emilie, Laune, Daniel, Blanchard, France, Le Pessot, Florence, Sabourin, Jean-Christophe, Bibeau, Frédéric

“…Sporadic or hereditary colorectal cancer (CRC) with microsatellite instability (MSI) is frequently characterized by inflammatory lymphocytic infiltration and…”
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PAI-1-dependent endothelial cell death determines severity of radiation-induced intestinal injury by Abderrahmani, Rym, François, Agnes, Buard, Valerie, Tarlet, Georges, Blirando, Karl, Hneino, Mohammad, Vaurijoux, Aurelie, Benderitter, Marc, Sabourin, Jean-Christophe, Milliat, Fabien

“…Normal tissue toxicity still remains a dose-limiting factor in clinical radiation therapy. Recently, plasminogen activator inhibitor type 1 (SERPINE1/PAI-1)…”
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