Search Results - "Sabourin, Jean‐Charles"
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RNA-Seq Analysis of Microglia Reveals Time-Dependent Activation of Specific Genetic Programs following Spinal Cord Injury
Published in Frontiers in molecular neuroscience (03-04-2017)“…Neurons have inherent competence to regrow following injury, although not spontaneously. Spinal cord injury (SCI) induces a pronounced neuroinflammation driven…”
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Asymmetric Distribution of GFAP in Glioma Multipotent Cells
Published in PloS one (08-03-2016)“…Asymmetric division (AD) is a fundamental mechanism whereby unequal inheritance of various cellular compounds during mitosis generates unequal fate in the two…”
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Early functional deficit and microglial disturbances in a mouse model of amyotrophic lateral sclerosis
Published in PloS one (25-04-2012)“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by selective motoneurons degeneration. There is today no clear-cut…”
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A Mesenchymal‐Like ZEB1+ Niche Harbors Dorsal Radial Glial Fibrillary Acidic Protein‐Positive Stem Cells in the Spinal Cord
Published in Stem cells (Dayton, Ohio) (01-11-2009)“…In humans and rodents the adult spinal cord harbors neural stem cells located around the central canal. Their identity, precise location, and specific…”
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A mono-allelic bivalent chromatin domain controls tissue-specific imprinting at Grb10
Published in The EMBO journal (08-10-2008)“…Genomic imprinting is a developmental mechanism that mediates parent‐of‐origin‐specific expression in a subset of genes. How the tissue specificity of…”
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Brca1 is expressed in human microglia and is dysregulated in human and animal model of ALS
Published in Molecular neurodegeneration (01-08-2015)“…There is growing evidence that microglia are key players in the pathological process of amyotrophic lateral sclerosis (ALS). It is suggested that microglia…”
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Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor
Published in Cell reports (Cambridge) (01-11-2016)“…During spinal cord development, astrocyte precursors arise from neuroepithelial progenitors, delaminate from the ventricular zone, and migrate toward their…”
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OCAM regulates embryonic spinal cord stem cell proliferation by modulating ErbB2 receptor
Published in PloS one (13-04-2015)“…The proliferation and differentiation of neural stem cells are tightly controlled by intrinsic and extrinsic cues. Cell adhesion molecules are increasingly…”
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Exogenous and Fibroblast Growth Factor 2/Epidermal Growth Factor–Regulated Endogenous Cytokines Regulate Neural Precursor Cell Growth and Differentiation
Published in Stem cells (Dayton, Ohio) (01-03-2006)“…Neurospheres (NSs) are clonal cellular aggregates composed of neural stem cells and progenitors. A comprehensive description of their proliferation and…”
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Spinal cord injury induces astroglial conversion towards neuronal lineage
Published in Molecular neurodegeneration (06-10-2016)“…Neurons have intrinsic capability to regenerate after lesion, though not spontaneously. Spinal cord injury (SCI) causes permanent neurological impairments…”
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Unlike physical exercise, modified environment increases the lifespan of SOD1G93A mice however both conditions induce cellular changes
Published in PloS one (20-09-2012)“…Amyotrophic lateral sclerosis (ALS) is characterized by a gradual muscular paralysis resulting from progressive motoneurons death. ALS etiology remains unknown…”
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OCAM Regulates Embryonic Spinal Cord Stem Cell Proliferation by Modulating ErbB2 Receptor
Published in PloS one (13-04-2015)Get full text
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Asymmetric Distribution of GFAP in Glioma Multipotent Cells
Published in PloS one (08-03-2016)Get full text
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Unlike Physical Exercise, Modified Environment Increases the Lifespan of SOD1.sup.G93A Mice However Both Conditions Induce Cellular Changes
Published in PloS one (20-09-2012)“…Background Amyotrophic lateral sclerosis (ALS) is characterized by a gradual muscular paralysis resulting from progressive motoneurons death. ALS etiology…”
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Asymmetric Distribution of GFAP in Glioma Multipotent Cells: e0151274
Published in PloS one (01-03-2016)“…Asymmetric division (AD) is a fundamental mechanism whereby unequal inheritance of various cellular compounds during mitosis generates unequal fate in the two…”
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Adult human spinal cord harbors neural precursor cells that generate neurons and glial cells in vitro
Published in Journal of neuroscience research (01-07-2008)“…Adult human and rodent brains contain neural stem and progenitor cells, and the presence of neural stem cells in the adult rodent spinal cord has also been…”
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Cochlear stem/progenitor cells from a postnatal cochlea respond to Jagged1 and demonstrate that notch signaling promotes sphere formation and sensory potential
Published in Mechanisms of development (01-08-2008)“…Hair cells and supporting cells of the mammalian cochlea terminally differentiate during development. Recent in vitro evidence suggests the presence of hair…”
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14-P004 A mesenchymal-like Zeb1+ niche harbors dorsal radial GFAP+ stem cells in the spinal cord
Published in Mechanisms of development (01-08-2009)Get full text
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