Search Results - "Sabnis, GJ"

Abstract P2-09-10: A new oral SERD AZD9496 for treatment of hormone dependent postmenopausal breast cancer by Sabnis, GJ, Kazi, A, Schech, A, Yu, S, Golubeva, O, Weir, H, Brodie, A

“…Treatment of hormone sensitive breast tumors with endocrine therapy such as antiestrogens or aromatase inhibitors has improved their clinical outcomes…”
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Abstract P1-07-01: Histone deacetylase inhibitor entinostat reverses epithelial to mesenchymal transition of breast cancer cells by reversing the repression of E-cadherin by Sabnis, GJ, Shah, P, Kazi, A, Gau, Y, Chumsri, S, Brodie, A

“…Loss of ERa in breast cancer correlates with poor prognosis, increased recurrence rates and higher incidence of metastasis. In our previous studies, we have…”
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Abstract PD05-03: HDAC Inhibitor Entinostat Restores Responsiveness of Letrozole Resistant MCF-7Ca Xenografts to AIs through Modulation of Her-2 by Sabnis, GJ, Kazi, A, Goloubeva, O, Brodie, AMH

“…Development of aromatase inhibitors (AIs) has significantly improved the treatment outcome of hormone responsive post-menopausal breast cancer. However, not…”
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The role of growth factor receptor pathways in human breast cancer cells adapted to long-term estrogen deprivation by SABNIS, Gauri J, JELOVAC, Danijela, LONG, Brian, BRODIE, Angela

“…To study the long-term effects of estrogen deprivation on breast cancer, MCF-7Ca human estrogen receptor-positive breast cancer cells stably transfected with…”
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Combination of HDACi entinostat (SNDX-275) with letrozole provides control over tumor growth in MDA-MB-231 xenograft model by Sabnis, GJ, Goloubeva, O, Macedo, LF, Gilani, R, Gediya, LK, Njar, VC, Brodie, AM

“…Abstract #6128 It is well established that approximately 75% of human breast cancers are ER+ and therefore treated with endocrine therapy. In a past few…”
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