Search Results - "Sabitri, Lamichhane"

Quantification of Cardiotonic Steroids Potentially Regulated by Paraoxonase 3 in a Rat Model of Chronic Kidney Disease Using UHPLC-Orbitrap-MS by Lamichhane, Sabitri, Mohammed, Chrysan J, Haller, Steven T, Kennedy, David J, Isailovic, Dragan

“…Endogenous cardiotonic steroids (CTSs), such as telocinobufagin (TCB) and marinobufagin (MBG) contain a lactone moiety critical to their binding and signaling…”
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A PON for All Seasons: Comparing Paraoxonase Enzyme Substrates, Activity and Action including the Role of PON3 in Health and Disease by Mohammed, Chrysan J, Lamichhane, Sabitri, Connolly, Jacob A, Soehnlen, Sophia M, Khalaf, Fatimah K, Malhotra, Deepak, Haller, Steven T, Isailovic, Dragan, Kennedy, David J

“…Paraoxonases (PONs) are a family of hydrolytic enzymes consisting of three members, PON1, PON2, and PON3, located on human chromosome 7. Identifying the…”
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Management and Outcome of Severe Sepsis and Septic Shock Patients by Lamichhane, Sabitri, Manandhar, Nayan, Dhakal, Shailendra, Shakya, Yagya Laxmi

“…Severe sepsis and septic shock are major causes of morbidity and mortality worldwide and need immediate medical attention. Early recognition, fluid…”
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UHPLC-MS Analyses of Cardiotonic Steroids in Rat Urine and Investigation of Their Hydrolysis by Paraoxonases by Lamichhane, Sabitri

“…Elevated levels of endogenous cardiotonic steroids (CTS), such as telocinobufagin (TCB) and marinobufagin (MBG), are observed in patients with chronic kidney…”
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Abstract 13166: Paraoxonase-3 Regulation of Cardiotonic Steroids Mediates Renal Injury and Dysfunction in a Dahl Salt Sensitive Model of Chronic Kidney Disease by Mohammed, Chrysan J, Lamichhane, Sabitri, Dube, Prabhatchandra, Soehnlen, Sophia, Connolly, Jacob, Kleinhenz, Andrew, Faleel, Dhilhani, Isailovic, Dragan, Malhotra, Deepak, Haller, Steven, Kennedy, David J

“…BackgroundParaoxonases (Pons) belong to a family of hydrolytic enzymes with 3 distinct isoformsPon 1, 2, and 3. While the physiologic substrates for Pons are…”
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Clinical Pharmacy Practice in Low-and Middle-income Countries; Special Focus on Nepal by Sitaram Khadka, Mahesh Khatri, Sabitri Lamichhane, Sagar Dhakal

“…The paradigm shift of pharmacy practice from the conventional compounding and dispensing role towards more advanced patient-centered care has a positive impact…”
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Rational design of metabolically stable HDAC inhibitors: An overhaul of trifluoromethyl ketones by Riddhidev, Banerjee, Endri, Karaj, Sabitri, Lamichhane, Kotsull, Lauren, N., Nishanth, Kuganesan, Dragan, Isailovic, Mary Kay H, Pflum, James, Slama, William, Taylor, L. M. Viranga, Tillekeratne

“…Epigenetic regulation of gene expression using histone deacetylase (HDAC) inhibitors is a promising strategy for developing new anticancer agents. The most…”
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Management and Outcome of Severe Sepsis and Septic Shock Patients Admitted to the Emergency Department in a Tertiary Hospital by Lamichhane, Sabitri, Manandhar, Nayan, Dhakal, Shailendra, Shakya, Yagya Laxmi

“…Background: Severe sepsis and septic shock are major causes of morbidity and mortality worldwide and need immediate medical attention. Early recognition, fluid…”
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Rational use of antimicrobials: a nationwide cross-sectional survey among people of Pakistan by Khadka, Sitaram, Hashmi, Furqan K., Yadav, Gopal K., Lamichhane, Sabitri, Giri, Santoshi, Tariq, Fatima, Amin, Sabahat, Zaheer, Warda, Akram, Kiran, Asghar, Ifra, Zahra, Kainat, Bajwa, Faiza, Ul-ain, Noor, Adnan, Muhammad A.J.

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