Search Results - "Sabino Strippoli"

Circulating extracellular vesicles expressing PD1 and PD-L1 predict response and mediate resistance to checkpoint inhibitors immunotherapy in metastatic melanoma by Serratì, Simona, Guida, Michele, Di Fonte, Roberta, De Summa, Simona, Strippoli, Sabino, Iacobazzi, Rosa Maria, Quarta, Alessandra, De Risi, Ivana, Guida, Gabriella, Paradiso, Angelo, Porcelli, Letizia, Azzariti, Amalia

“…The immunotherapy with immune checkpoints inhibitors (ICI) has changed the life expectancy in metastatic melanoma (MM) patients. Nevertheless, several patients…”
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The β-adrenergic receptor antagonist propranolol offsets resistance mechanisms to chemotherapeutics in diverse sarcoma subtypes: a pilot study by Porcelli, Letizia, Garofoli, Marianna, Di Fonte, Roberta, Fucci, Livia, Volpicella, Mariateresa, Strippoli, Sabino, Guida, Michele, Azzariti, Amalia

“…Standard chemotherapy for soft tissue sarcomas has shown limited efficacy. Here, we sought to evaluate whether β-adrenergic receptor (β-AR) signalling…”
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A deep learning model based on whole slide images to predict disease-free survival in cutaneous melanoma patients by Comes, Maria Colomba, Fucci, Livia, Mele, Fabio, Bove, Samantha, Cristofaro, Cristian, De Risi, Ivana, Fanizzi, Annarita, Milella, Martina, Strippoli, Sabino, Zito, Alfredo, Guida, Michele, Massafra, Raffaella

“…The application of deep learning on whole-slide histological images (WSIs) can reveal insights for clinical and basic tumor science investigations. Finding…”
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Case Report: Autoimmune Pemphigus Vulgaris in a Patient Treated With Cemiplimab for Multiple Locally Advanced Cutaneous Squamous Cell Carcinoma by Buquicchio, Rosalba, Mastrandrea, Valentina, Strippoli, Sabino, Quaresmini, Davide, Guida, Michele, Filotico, Raffaele

“…Pemphigus vulgaris (PV) is a rare and severe autoimmune blistering disorder affecting the skin and mucous membranes, characterized by the production of…”
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Circulating extracellular vesicles are monitoring biomarkers of anti-PD1 response and enhancer of tumor progression and immunosuppression in metastatic melanoma by Serratì, Simona, Di Fonte, Roberta, Porcelli, Letizia, De Summa, Simona, De Risi, Ivana, Fucci, Livia, Ruggieri, Eustachio, Marvulli, Tommaso Maria, Strippoli, Sabino, Fasano, Rossella, Rafaschieri, Tania, Guida, Gabriella, Guida, Michele, Azzariti, Amalia

“…Abstract Background Clinical drawback in checkpoint inhibitors immunotherapy (ICI) of metastatic melanoma (MM) is monitoring clinical benefit. Soluble forms of…”
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Basal and one-month differed neutrophil, lymphocyte and platelet values and their ratios strongly predict the efficacy of checkpoint inhibitors immunotherapy in patients with advanced BRAF wild-type melanoma by Guida, Michele, Bartolomeo, Nicola, Quaresmini, Davide, Quaglino, Pietro, Madonna, Gabriele, Pigozzo, Jacopo, Di Giacomo, Anna Maria, Minisini, Alessandro Marco, Tucci, Marco, Spagnolo, Francesco, Occelli, Marcella, Ridolfi, Laura, Queirolo, Paola, De Risi, Ivana, Valente, Monica, Sciacovelli, Angela Monica, Chiarion Sileni, Vanna, Ascierto, Paolo Antonio, Stigliano, Lucia, Strippoli, Sabino

“…To evaluate the capability of basal and one-month differed white blood cells (WBC), neutrophil, lymphocyte and platelet values and their ratios…”
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Case report: Is severe toxicity the price to pay for high sensitivity to checkpoint inhibitors immunotherapy in desmoplastic melanoma? by Squicciarini, Teresa, Villani, Rossella, Apollonio, Benedetta, Fucci, Livia, Zambetti, Milena, Rossini, Michele, Pinto, Rosamaria, Tommasi, Stefania, De Roma, Ileana, Strippoli, Sabino, Guida, Michele

“…Desmoplastic melanoma (DM) is a rare subtype of melanoma characterized by high immunogenicity which makes it particularly suitable for immune checkpoint…”
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Cellular analysis of bronchoalveolar lavage fluid to narrow differential diagnosis of checkpoint inhibitor-related pneumonitis in metastatic melanoma by Strippoli, Sabino, Fucci, Livia, Negri, Antonio, Putignano, Daniela, Cisternino, Marco Luigi, Napoli, Gaetano, Filannino, Ruggiero, De Risi, Ivana, Sciacovelli, Angela Monica, Guida, Michele

“…The diagnosis of check-point inhibitor-related pneumonitis (CIP) relies on radiological and clinical patterns which are not specific and can mimic other…”
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Is immunohistochemistry of BRAF V600E useful as a screening tool and during progression disease of melanoma patients? by Schirosi, Laura, Strippoli, Sabino, Gaudio, Francesca, Graziano, Giusi, Popescu, Ondina, Guida, Michele, Simone, Giovanni, Mangia, Anita

“…In clinical practice the gold standard method to assess BRAF status in patients with metastatic melanoma is based on molecular assays. Recently, a…”
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Cemiplimab in an Elderly Frail Population of Patients With Locally Advanced or Metastatic Cutaneous Squamous Cell Carcinoma: A Single-Center Real-Life Experience From Italy by Strippoli, Sabino, Fanizzi, Annarita, Quaresmini, Davide, Nardone, Annalisa, Armenio, Andrea, Figliuolo, Francesco, Filotico, Raffaele, Fucci, Livia, Mele, Fabio, Traversa, Michele, De Luca, Federica, Montagna, Elisabetta Sara, Ruggieri, Eustachio, Ferraiuolo, Simona, Macina, Francesco, Tommasi, Stefania, Sciacovelli, Angela Monica, De Risi, Ivana, Albano, Anna, Massafra, Raffaella, Guida, Michele

“…Cutaneous squamous cell carcinoma (CSCC) is the second most common skin cancer whose incidence is growing parallel to the lengthening of the average lifespan…”
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uPAR+ extracellular vesicles: a robust biomarker of resistance to checkpoint inhibitor immunotherapy in metastatic melanoma patients by Porcelli, Letizia, Guida, Michele, De Summa, Simona, Di Fonte, Roberta, De Risi, Ivana, Garofoli, Marianna, Caputo, Mariapia, Negri, Antonio, Strippoli, Sabino, Serratì, Simona, Azzariti, Amalia

“…BackgroundEmerging evidence has highlighted the importance of extracellular vesicle (EV)-based biomarkers of resistance to immunotherapy with checkpoint…”
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Electrochemotherapy as a Trigger to Overcome Primary Resistance to Anti-PD-1 Treatment: A Case Report of Melanoma of the Scalp by Quaresmini, Davide, Di Lauro, Alessandra, Fucci, Livia, Strippoli, Sabino, De Risi, Ivana, Sciacovelli, Angela Monica, Albano, Anna, Achille, Gaetano, Montepara, Massimo, Russo, Sabino, Tassone, Gabriella, Guida, Michele

“…Immunotherapy with immune checkpoint inhibitors is one of the main therapies for advanced melanoma. Nevertheless, albeit remarkable, immunotherapy results are…”
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The search for a melanoma-tailored chemotherapy in the new era of personalized therapy: a phase II study of chemo-modulating temozolomide followed by fotemustine and a cooperative study of GOIM (Gruppo Oncologico Italia Meridionale) by Guida, Michele, Tommasi, Stefania, Strippoli, Sabino, Natalicchio, Maria Iole, De Summa, Simona, Pinto, Rosamaria, Cramarossa, Antonio, Albano, Anna, Pisconti, Salvatore, Aieta, Michele, Ridolfi, Ruggiero, Azzariti, Amalia, Guida, Gabriella, Lorusso, Vito, Colucci, Giusepe

“…It is frequently asked whether chemotherapy can still play a role in metastatic melanoma considering the effectiveness of the available drugs today, including…”
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Survey of the impact of BOLT-trial data on oncologists’ and dermatologists’ decision-making in treating patients with locally advanced basal cell carcinoma by Scarpato, Luigi, Palla, Marco, Strippoli, Sabino, Tagliaferri, Luca, Fania, Luca, Saponara, Maristella, Carbone, Anna, Spagnolo, Francesco, Silvestri, Flavia, Ascierto, Paolo Antonio

“…Basal cell carcinoma (BCC) is the most common malignant tumour in white populations. Multiple studies demonstrated that the aberrant activation of Hedgehog…”
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Case Report: Lymphocytosis Associated With Fatal Hepatitis in a Thymoma Patient Treated With Anti-PD1: New Insight Into the Immune-Related Storm by Argentiero, Antonella, Solimando, Antonio Giovanni, Ungaro, Valentina, Laforgia, Mariarita, Strippoli, Sabino, Pinto, Dario, Negri, Antonio, Ferraiuolo, Simona, Zito, Alfredo, Guida, Michele

“…Recent advances in tumor immunotherapy have made it possible to efficiently unleash immune effectors, reacting against neoplastic cells. Although these…”
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Cervical cancer benefits from trabectedin combination with the β-blocker propranolol: in vitro and ex vivo evaluations in patient-derived organoids by Di Fonte, Roberta, Strippoli, Sabino, Garofoli, Marianna, Cormio, Gennaro, Serratì, Simona, Loizzi, Vera, Fasano, Rossella, Arezzo, Francesca, Volpicella, Mariateresa, Derakhshani, Afshin, Guida, Michele, Porcelli, Letizia, Azzariti, Amalia

“…Cervical cancer (CC) is characterized by genomic alterations in DNA repair genes, which could favor treatment with agents causing DNA double-strand breaks…”
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Proteomic profile and in silico analysis in metastatic melanoma with and without BRAF mutation by Garrisi, Vito Michele, Strippoli, Sabino, De Summa, Simona, Pinto, Rosamaria, Perrone, Antonella, Guida, Gabriella, Azzariti, Amalia, Guida, Michele, Tommasi, Stefania, Stefania, Tommasi

“…Selective inhibitors of BRAF, vemurafenib and dabrafenib are the standard of care for metastatic melanoma patients with BRAF V600, while chemotherapy continued…”
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An Italian Retrospective Survey on Bone Metastasis in Melanoma: Impact of Immunotherapy and Radiotherapy on Survival by Mannavola, Francesco, Mandala, Mario, Todisco, Annalisa, Sileni, Vanna Chiarion, Palla, Marco, Minisini, Alessandro Marco, Pala, Laura, Morgese, Francesca, Di Guardo, Lorenza, Stucci, Luigia Stefania, Guida, Michele, Indini, Alice, Quaglino, Pietro, Ferraresi, Virginia, Marconcini, Riccardo, Tronconi, Maria Chiara, Rossi, Ernesto, Nigro, Olga, Occelli, Marcella, Cortellini, Alessio, Quadrini, Silvia, Palmieri, Giuseppe, Pigozzo, Jacopo, Ascierto, Paolo Antonio, Vitale, Maria Grazia, Strippoli, Sabino, Ferrucci, Pier Francesco, Berardi, Rossana, Randon, Giovanni, Cardone, Pietro, Schinzari, Giovanni, Silvestris, Franco, Tucci, Marco

“…We performed a multicenter retrospective observational study to investigate the impact of clinical-pathological features and therapeutic strategies on both the…”
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Corrigendum: The molecular tumor board as a step in cancer patient management: a southern Italian experience by Tommasi, Stefania, Maurmo, Leonarda, Rizzo, Alessandro, Carella, Claudia, Ranieri, Girolamo, De Summa, Simona, Mannavola, Francesco, Chiurì, Vincenzo Emanuele, Guida, Michele, Nisi, Claudia, Montrone, Michele, Giotta, Francesco, Patruno, Margherita, Lacalamita, Rosanna, Pilato, Brunella, Zito, Francesco Alfredo, Fucci, Livia, Coppola, Claudio Antonio, Ditonno, Paolo, Nardulli, Patrizia, Quaresmini, Davide, Strippoli, Sabino

“…[This corrects the article DOI: 10.3389/fmed.2024.1432628.].[This corrects the article DOI: 10.3389/fmed.2024.1432628.]…”
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The molecular tumor board as a step in cancer patient management: a southern Italian experience by Tommasi, Stefania, Maurmo, Leonarda, Rizzo, Alessandro, Carella, Claudia, Ranieri, Girolamo, De Summa, Simona, Mannavola, Francesco, Chiurì, Vincenzo Emanuele, Guida, Michele, Nisi, Claudia, Montrone, Michele, Giotta, Francesco, Patruno, Margherita, Lacalamita, Rosanna, Pilato, Brunella, Zito, Francesco Alfredo, Fucci, Livia, Coppola, Claudio Antonio, Ditonno, Paolo, Nardulli, Patrizia, Quaresmini, Davide, Strippoli, Sabino

“…The management of cancer patients follows a Diagnostic Therapeutic and Care Pathway (PDTA) approach, aimed at achieving the optimal balance between care and…”
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