Search Results - "Sabin, Juan"
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The Landscape of Osteocalcin Proteoforms Reveals Distinct Structural and Functional Roles of Its Carboxylation Sites
Published in Journal of the American Chemical Society (09-10-2024)“…Human osteocalcin (OC) undergoes reversible, vitamin K-dependent γ-carboxylation at three glutamic acid residues, modulating its release from bones and its…”
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2
AFFINImeter: A software to analyze molecular recognition processes from experimental data
Published in Analytical biochemistry (15-07-2019)“…The comprehension of molecular recognition phenomena demands the understanding of the energetic and kinetic processes involved. General equations valid for the…”
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3
Targeted removal of the FA2 site on human albumin prevents fatty acid–mediated inhibition of Zn2+ binding
Published in Journal of lipid research (01-06-2024)“…Zinc is required for virtually all biological processes. In plasma, Zn2+ is predominantly transported by human serum albumin (HSA), which possesses two…”
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4
The neuronal calcium sensor NCS-1 regulates the phosphorylation state and activity of the Gα chaperone and GEF Ric-8A
Published in eLife (29-11-2023)“…The neuronal calcium sensor 1 (NCS-1), an EF-hand Ca binding protein, and Ric-8A coregulate synapse number and probability of neurotransmitter release…”
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5
The Use of ITC and the Software AFFINImeter for the Quantification of the Anticoagulant Pentasaccharide in Low Molecular Weight Heparin
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…In this chapter, we describe an original protocol based on ITC experiments and data analysis with the software AFFINImeter to get information of heparin-AT…”
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6
On the structure and stability of novel cationic DPPC liposomes doped with gemini surfactants
Published in Journal of molecular liquids (15-11-2022)“…[Display omitted] •A novel formulation of cationic liposomes was studied by mixing DPPC with cationic gemini surfactants.•The phase transition was interpreted…”
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7
Micellization thermodynamic behavior of gemini cationic surfactants. Modeling its adsorption at air/water interface
Published in Journal of molecular liquids (15-06-2020)“…Self-assembly structures of gemini surfactants are characterized, among others, for their low CMC. This characteristic could be due to great hydrophobic parts…”
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8
Double Charge Inversion in Polyethylenimine-Decorated Liposomes
Published in Langmuir (17-07-2012)“…The study of the interaction of a cationic polymer as PEI with phospholipids membranes is of special relevance for gene therapy because the PEI is a potential…”
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9
Bis-pseudorotaxane Formation of Perylene Bisimide-Linked [60]Fullerene Dumbbell-Like Molecules with [10]Cycloparaphenylene
Published in Organic Materials (01-08-2022)“…Two [60]fullerene dumbbell-like molecules with a single or double perylene-3,4,9,10-tetracarboxylic acid bisimide (PBI) linker were synthesized to study the…”
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10
Thermodynamics of clay–drug complex dispersions: Isothermal titration calorimetry and high-performance liquid chromatography
Published in Journal of pharmaceutical analysis (01-02-2020)“…An understanding of the thermodynamics of the complexation process utilized in sustaining drug release in clay matrices is of great importance. Several…”
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Insertion of semifluorinated diblocks on DMPC and DPPC liposomes. Influence on the gel and liquid states of the bilayer
Published in Journal of colloid and interface science (15-08-2010)“…Schematic representations of the configuration of liposomes formed by DPPC and F 6H 16 at 1:2 lipid/F n H m molar ratio. Differential Scanning Calorimetry…”
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12
Effects of Fluorinated and Hydrogenated Surfactants on Human Serum Albumin at Different pHs
Published in Biomacromolecules (01-01-2006)“…Complexation between human serum albumin (HSA) and two different surfactants, one fully fluorinated (sodium perfluorooctanoate, SPFO) and one fully…”
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Thermodynamic and Kinetic Analysis of Isothermal Titration Calorimetry Experiments by Using KinITC in AFFINImeter
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…Standard molecular binding isothermal titration calorimetric (ITC) experiments are designed to get thermodynamic information: changes in Gibbs energy,…”
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14
DNA–chitosan complexation: A dynamic light scattering study
Published in Colloids and surfaces. A, Physicochemical and engineering aspects (01-05-2009)“…The interactions of DNA in mixed solutions with cationic macromolecular compounds have attracted great interest of biomedical sciences, in particular for…”
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15
Influence of temperature on the colloidal stability of the F-DPPC and DPPC liposomes induced by lanthanum ions
Published in Journal of colloid and interface science (01-02-2012)“…[Display omitted] ► Influence of ions La3+ on the colloidal stability of DPPC and F-DPPC liposomes. ► Dynamic light scattering and electrophoretic mobility was…”
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16
On the Effect of Ca2+ and La3+ on the Colloidal Stability of Liposomes
Published in Langmuir (22-11-2005)“…This work deals with the effect of Ca2+ and La3+ on the colloidal stability of phosphatidylcholine (PC) liposomes in aqueous media. As physical techniques,…”
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17
Interactions between DMPC Liposomes and the Serum Blood Proteins HSA and IgG
Published in The journal of physical chemistry. B (12-02-2009)“…The interaction between two serum blood proteins, namely human serum albumin (HSA) and human immunoglobulin G (IgG), with…”
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18
New insights on the mechanism of polyethylenimine transfection and their implications on gene therapy and DNA vaccines
Published in Colloids and surfaces, B, Biointerfaces (01-02-2022)“…Polyethylenimine (PEI) has been demonstrated as an efficient DNA delivery vehicle both in vitro and in vivo. There is a consensus that PEI-DNA complexes enter…”
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19
Extending ITC to Kinetics with kinITC
Published in Methods in enzymology (01-01-2016)“…Isothermal titration calorimetry (ITC) has long been used for kinetic studies in chemistry, but this remained confined to enzymatic studies in the biological…”
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MUC1 Glycopeptide Vaccine Modified with a GalNAc Glycocluster Targets the Macrophage Galactose C‑type Lectin on Dendritic Cells to Elicit an Improved Humoral Response
Published in Journal of the American Chemical Society (21-06-2023)“…Mucin expression and glycosylation patterns on cancer cells differ markedly from healthy cells. Mucin 1 (MUC1) is overexpressed in several solid tumors and…”
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