Search Results - "Sabia, Rocchina"
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Dynamic high performance liquid chromatography on chiral stationary phases. Low temperature separation of the interconverting enantiomers of diazepam, flunitrazepam, prazepam and tetrazepam
Published in Journal of Chromatography A (10-10-2014)“…•The conformational enantiomers of diazepam were resolved by cryo-HPLC on Whelk-O1.•Prazepam, tetrazepam and flunitrazepam were also resolved on the Whelk-O1…”
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Helical Sense-Responsive and Substituent-Sensitive Features in Vibrational and Electronic Circular Dichroism, in Circularly Polarized Luminescence, and in Raman Spectra of Some Simple Optically Active Hexahelicenes
Published in Journal of physical chemistry. C (23-01-2014)“…Four different hexahelicenes, 5-aza-hexahelicene (1), hexahelicene (2), 2-methyl-hexahelicene (3), and 2-bromo-hexahelicene (4), were prepared and their…”
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3
Chiroptical properties of the ground and excited states of two thia-bridged triarylamine heterohelicenes
Published in Journal of photochemistry and photobiology. A, Chemistry. (01-12-2016)“…[Display omitted] •Chiroptical Spectra performed on Thia-bridged Triarylamino Heterohelicenes (TBTA-HELI).•TBTA-HELI are configurationally more stable than…”
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Degradation of Post-consumer PLA: Hydrolysis of Polymeric Matrix and Oligomers Stabilization in Aqueous Phase
Published in Journal of polymers and the environment (01-12-2018)“…Degradation of post-consumer PLA to lactic acid was analysed in order to assess the economic feasibility of the PLA chemical recycling process. Hydrolysis of…”
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High-Performance Liquid Chromatographic Resolution of Neutral and Cationic Hetero[6]Helicenes
Published in Chirality (New York, N.Y.) (01-04-2016)“…Cationic hetero[6]helicenes 1+, 2+ and 3+ have been recently disclosed. Herein we report on their enantiomeric separation using high‐performance liquid…”
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Chromatographic separation of the interconverting enantiomers of imidazo- and triazole-fused benzodiazepines
Published in Journal of Chromatography A (21-06-2021)“…•An application of dynamic HPLC to the study of stereolabile chiral benzodiazepines.•Dynamic HPLC on CSPs using water rich media is described.•Energy barriers…”
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7
“Click” hyaluronan based nanohydrogels as multifunctionalizable carriers for hydrophobic drugs
Published in Carbohydrate polymers (15-10-2017)“…•Amphiphilic polymers prepared with hyaluronan and riboflavin were synthesized by a click-chemistry reaction.•These products were able, in aqueous media, to…”
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Total Synthesis of (±)-Kuwanol E
Published in Journal of natural products (Washington, D.C.) (28-10-2016)“…The total synthesis of the Diels–Alder-type adducts (±)-kuwanol E and the heptamethyl ether derivative of (±)-kuwanon Y has been accomplished via a convergent…”
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Dynamic Behavior of Clobazam on High-Performance Liquid Chromatography Chiral Stationary Phases
Published in Chirality (New York, N.Y.) (01-01-2016)“…Clobazam, a 1,5‐benzodiazepin‐2,4‐dione, is a chiral molecule because its ground state conformation features a nonplanar seven‐membered ring lacking reflection…”
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New amide derivatives of Probenecid as selective inhibitors of carbonic anhydrase IX and XII: Biological evaluation and molecular modelling studies
Published in Bioorganic & medicinal chemistry (01-07-2015)“…[Display omitted] Novel amide derivatives of Probenecid were synthesized and discovered to act as potent and selective inhibitors of the human carbonic…”
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Equilibrium condition and stabilization kinetics of lactic acid oligomers in aqueous solutions
Published in Canadian journal of chemical engineering (01-05-2017)“…Lactic acid is one of the most important compounds in the field of bio‐renewable chemicals. Lactic acid is present in nature but can also be produced by…”
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Quantitation of human milk proteins and their glycoforms using multiple reaction monitoring (MRM)
Published in Analytical and bioanalytical chemistry (01-01-2017)“…Human milk plays a substantial role in the child growth, development and determines their nutritional and health status. Despite the importance of the proteins…”
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3,5-Dinitrobenzoyl-9-amino-9-deoxy-9-epiquinine as Pirkle-Anion Exchange Hybrid-Type Chiral Selector in High-Performance Liquid Chromatography
Published in Chromatographia (01-05-2017)“…A new chiral stationary phase was designed by introducing 9-amino-9-deoxy-9-epiquinine, one of the most versatile organocatalysts in asymmetric synthesis, as…”
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Polyaspartamide-Doxorubicin Conjugate as Potential Prodrug for Anticancer Therapy
Published in Pharmaceutical research (01-05-2015)“…ABSTRACT Purpose To synthesize a new polymeric prodrug based on α,β-poly(N-2-hydroxyethyl)(2-aminoethylcarbamate)-d,l-aspartamide copolymer bearing amine…”
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The dynamic chromatographic behavior of tri-o-thymotide on HPLC chiral stationary phases
Published in Chemical communications (Cambridge, England) (28-03-2012)“…The interconverting stereoisomers of tri-o-thymotide have been separated by HPLC on chiral stationary phases and the temperature dependence of the dynamic…”
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