Search Results - "Sabharwal, Vidur"

Crowd Control: Effects of Physical Crowding on Cargo Movement in Healthy and Diseased Neurons by Sabharwal, Vidur, Koushika, Sandhya P.

“…High concentration of cytoskeletal filaments, organelles, and proteins along with the space constraints due to the axon’s narrow geometry lead inevitably to…”
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UNC-16 alters DLK-1 localization and negatively regulates actin and microtubule dynamics in Caenorhabditis elegans regenerating neurons by Kulkarni, Sucheta S, Sabharwal, Vidur, Sheoran, Seema, Basu, Atrayee, Matsumoto, Kunihiro, Hisamoto, Naoki, Ghosh-Roy, Anindya, Koushika, Sandhya P

“…Abstract Neuronal regeneration after injury depends on the intrinsic growth potential of neurons. Our study shows that UNC-16, a Caenorhabditis elegans JIP3…”
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First person – Vidur Sabharwal by Sabharwal, V

“…ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping researchers…”
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F-box protein FBXB-65 regulates anterograde transport of the kinesin-3 motor UNC-104 through a PTM near its cargo-binding PH domain by Sabharwal, Vidur, Boyanapalli, Sri Padma Priya, Shee, Amir, Nonet, Michael L, Nandi, Amitabha, Chaudhuri, Debasish, Koushika, Sandhya P

“…Axonal transport in neurons is essential for cargo movement between the cell body and synapses. Caenorhabditis elegans UNC-104 and its homolog KIF1A are…”
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let-7 miRNA controls CED-7 homotypic adhesion and EFF-1–mediated axonal self-fusion to restore touch sensation following injury by Basu, Atrayee, Dey, Shirshendu, Puri, Dharmendra, Saha, Nilanjana Das, Sabharwal, Vidur, Thyagarajan, Pankajam, Srivastava, Prerna, Koushika, Sandhya Padmanabhan, Ghosh-Roy, Anindya

“…Neuronal injury often leads to devastating consequences such as loss of senses or locomotion. Restoration of function after injury relies on whether the…”
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UNC-16/JIP3 and UNC-76/FEZ1 limit the density of mitochondria in C. elegans neurons by maintaining the balance of anterograde and retrograde mitochondrial transport by Sure, Guruprasada Reddy, Chatterjee, Anusheela, Mishra, Nikhil, Sabharwal, Vidur, Devireddy, Swathi, Awasthi, Anjali, Mohan, Swetha, Koushika, Sandhya P.

“…We investigate the role of axonal transport in regulating neuronal mitochondrial density. We show that the density of mitochondria in the touch receptor neuron…”
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UNC-104 transport properties are robust and independent of changes in its cargo binding by Shee, Amir, Sabharwal, Vidur, Koushika, Sandhya P, Nandi, Amitabha, Chaudhuri, Debasish

“…Cargo distribution within eukaryotic cells relies on the active transport mechanisms driven by molecular motors. Despite their critical role, the intricate…”
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