Search Results - "Sabek, Omaima"

265.2: Assessing the potency of autologous MSCs by correlating serum IDO levels and regulatory T cell in living-donor kidney transplant recipients by Sabek, Omaima, Sabek, Omaima M, Beamish, Christine, Edlibi, Adib, Osama Gaber, A.

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Induction of IAPP amyloid deposition and associated diabetic abnormalities by a prion-like mechanism by Mukherjee, Abhisek, Morales-Scheihing, Diego, Salvadores, Natalia, Moreno-Gonzalez, Ines, Gonzalez, Cesar, Taylor-Presse, Kathleen, Mendez, Nicolas, Shahnawaz, Mohammad, Gaber, A Osama, Sabek, Omaima M, Fraga, Daniel W, Soto, Claudio

“…Although a large proportion of patients with type 2 diabetes (T2D) accumulate misfolded aggregates composed of the islet amyloid polypeptide (IAPP), its role…”
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Osteocalcin Effect on Human β-Cells Mass and Function by Sabek, Omaima M, Nishimoto, Satoru Ken, Fraga, Daniel, Tejpal, Neelam, Ricordi, Camillo, Gaber, A. O

“…The osteoblast-specific hormone osteocalcin (OC) was found to regulate glucose metabolism, fat mass, and β-cell proliferation in mice. Here, we investigate the…”
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Human pancreatic microenvironment promotes β-cell differentiation via non-canonical WNT5A/JNK and BMP signaling by Chmielowiec, Jolanta, Szlachcic, Wojciech J., Yang, Diane, Scavuzzo, Marissa A., Wamble, Katrina, Sarrion-Perdigones, Alejandro, Sabek, Omaima M., Venken, Koen J. T., Borowiak, Malgorzata

“…In vitro derivation of pancreatic β-cells from human pluripotent stem cells holds promise as diabetes treatment. Despite recent progress, efforts to generate…”
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High variability in short and long-term recovery kinetic of blood cell count and blood chemistry in a partial body irradiation mouse model by Tang, Tien T, Zawaski, Janice A, Sabek, Omaima M, Gaber, M Waleed

“…In the aftermath of a nuclear disaster or accident, survivors will suffer from radiation-induced normal tissue damage. Recovery after radiation exposure is…”
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3D Printed Vascularized Device for Subcutaneous Transplantation of Human Islets by Farina, Marco, Ballerini, Andrea, Fraga, Daniel W., Nicolov, Eugenia, Hogan, Matthew, Demarchi, Danilo, Scaglione, Francesco, Sabek, Omaima M., Horner, Philip, Thekkedath, Usha, Gaber, Osama A., Grattoni, Alessandro

“…Transplantation of pancreatic islets or stem cell derived insulin secreting cells is an attractive treatment strategy for diabetes. However, islet…”
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Modulation of naïve mesenchymal stromal cells by extracellular vesicles derived from insulin-producing cells: an in vitro study by Gabr, Mahmoud M., El-Halawani, Sawsan M., Refaie, Ayman F., Khater, Sherry M., Ismail, Amani M., Karras, Mary S., Magar, Raghda W., Sayed, Shorouk El, Kloc, Malgorzata, Uosef, Ahmed, Sabek, Omaima M., Ghoneim, Mohamed A.

“…This study was to determine whether extracellular vesicles (EVs) derived from insulin-producing cells (IPCs) can modulate naïve mesenchymal stromal cells…”
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Osteocalcin Protects Against Nonalcoholic Steatohepatitis in a Mouse Model of Metabolic Syndrome by Gupte, Anisha A, Sabek, Omaima M, Fraga, Daniel, Minze, Laurie J, Nishimoto, Satoru K, Liu, Joey Z, Afshar, Solmaz, Gaber, Lillian, Lyon, Christopher J, Gaber, A. Osama, Hsueh, Willa A

“…Nonalcoholic fatty liver disease, particularly its more aggressive form, nonalcoholic steatohepatitis (NASH), is associated with hepatic insulin resistance…”
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From Mesenchymal Stromal/Stem Cells to Insulin-Producing Cells: Immunological Considerations by Refaie, Ayman F., Elbassiouny, Batoul L., Kloc, Malgorzata, Sabek, Omaima M., Khater, Sherry M., Ismail, Amani M., Mohamed, Rania H., Ghoneim, Mohamed A.

“…Mesenchymal stem cell (MSC)-based therapy for type 1 diabetes mellitus (T1DM) has been the subject matter of many studies over the past few decades. The wide…”
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Radiation-Induced Astrogliosis and Blood-Brain Barrier Damage Can Be Abrogated Using Anti-TNF Treatment by Wilson, Christy M., Ph.D, Gaber, M. Waleed, Ph.D, Sabek, Omaima M., Ph.D, Zawaski, Janice A., M.S, Merchant, Thomas E., D.O., Ph.D

“…Purpose In this article, we investigate the role of tumor necrosis factor-alpha (TNF) in the initiation of acute damage to the blood-brain barrier (BBB) and…”
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Cognitive and Imaging Differences After Proton and Photon Whole Brain Irradiation in a Preclinical Model by Tang, Tien T., Zawaski, Janice A., Kesler, Shelli, Beamish, Christine A., Inoue, Taeko, Perez, Emma C., Bronk, Lawrence, Poenisch, Falk, Briere, Tina M., Sabek, Omaima M., Grosshans, David R., Waleed Gaber, M.

“…Compared with photon cranial radiation therapy (X-CRT), proton cranial radiation therapy (P-CRT) offers potential advantages in limiting radiation-induced…”
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Characterization of a nanogland for the autotransplantation of human pancreatic islets by Sabek, Omaima M, Ferrati, Silvia, Fraga, Daniel W, Sih, Juliana, Zabre, Erika V, Fine, Daniel H, Ferrari, Mauro, Gaber, A Osama, Grattoni, Alessandro

“…Despite the clinical success of pancreatic islet transplantation, graft function is frequently lost over time due to islet dispersion, lack of…”
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NF-κB Blockade by NEMO Binding Domain Peptide Ameliorates Inflammation and Neurobehavioral Sequelae After Cranial Radiation Therapy in Juvenile Mice by Beamish, Christine A., Zawaski, Janice A., Inoue, Taeko, Sarkar, Poonam, Grosshans, David R., Sabek, Omaima M., Gaber, M. Waleed

“…Cranial radiation therapy (CRT) is a common treatment for pediatric brain tumor patients. However, side effects include significant neurobehavioral dysfunction…”
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Differentiation of Heterogeneous Radiation Exposure Using Hematology and Blood Chemistry by Gaber, M. Waleed, Rodgers, Shaefali P., Tang, Tien T., Sabek, Omaima M., Zawaski, Janice A.

“…In the aftermath of a nuclear incident, survivors will suffer the deleterious effects from acute radiation exposure. The majority of those affected would have…”
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Variability in endocrine cell identity in patients with chronic pancreatitis undergoing islet autotransplantation by Beamish, Christine A., Gaber, A. Osama, Afshar, Solmaz F., Fraga, Daniel W., Hamilton, Dale J., Sabek, Omaima M.

“…Beta‐cell dedifferentiation as shown by cellular colocalization of insulin with glucagon and/or vimentin, and decreased expression of MAFA and/or urocortin3…”
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Imaging Radiation-Induced Gastrointestinal, Bone Marrow Injury and Recovery Kinetics Using 18F-FDG PET by Tang, Tien T, Rendon, David A, Zawaski, Janice A, Afshar, Solmaz F, Kaffes, Caterina K, Sabek, Omaima M, Gaber, M Waleed

“…Positron emission tomography using 18F-Fluro-deoxy-glucose (18F-FDG) is a useful tool to detect regions of inflammation in patients. We utilized this imaging…”
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Exercise ameliorates neurocognitive impairments in a translational model of pediatric radiotherapy by Sahnoune, Iman, Inoue, Taeko, Kesler, Shelli R, Rodgers, Shaefali P, Sabek, Omaima M, Pedersen, Steen E, Zawaski, Janice A, Nelson, Katharine H, Ris, M Douglas, Leasure, J Leigh, Gaber, M Waleed

“…While cranial radiation therapy (CRT) is an effective treatment, healthy areas surrounding irradiation sites are negatively affected. Frontal lobe functions…”
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Effect of Brain Tumor Presence During Radiation on Tissue Toxicity: Transcriptomic and Metabolic Changes by Zawaski, Janice A., Sabek, Omaima M., Voicu, Horatiu, Eastwood Leung, Hon-Chiu, Gaber, M. Waleed

“…Radiation therapy (RT) causes functional and transcriptomic changes in the brain; however, most studies have been carried out in normal rodent brains. Here,…”
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Pretransplant HOMA-β Is Predictive of Insulin Independence in 7 Patients With Chronic Pancreatitis Undergoing Islet Autotransplantation by Beamish, Christine A., Gaber, A. Osama, Fraga, Daniel W., Hamilton, Dale J., Sabek, Omaima M.

“…Background. Islet and β-cell function is intrinsic to glucose homeostasis. Pancreatectomy and islet autotransplantation (PIAT) for chronic pancreatitis (CP)…”
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Three-dimensional printed polymeric system to encapsulate human mesenchymal stem cells differentiated into islet-like insulin-producing aggregates for diabetes treatment by Sabek, Omaima M, Farina, Marco, Fraga, Daniel W, Afshar, Solmaz, Ballerini, Andrea, Filgueira, Carly S, Thekkedath, Usha R, Grattoni, Alessandro, Gaber, A Osama

“…Diabetes is one of the most prevalent, costly, and debilitating diseases in the world. Pancreas and islet transplants have shown success in re-establishing…”
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